Gene Review:
aur - aurora
Drosophila melanogaster
Synonyms:
87A7-9/2, Aur-A, AurA, CG3068, Dmel\CG3068, ...
- Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Glover, D.M., Leibowitz, M.H., McLean, D.A., Parry, H. Cell (1995)
- Mitotic mechanics: the auroras come into view. Andrews, P.D., Knatko, E., Moore, W.J., Swedlow, J.R. Curr. Opin. Cell Biol. (2003)
- Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Lee, C.Y., Andersen, R.O., Cabernard, C., Manning, L., Tran, K.D., Lanskey, M.J., Bashirullah, A., Doe, C.Q. Genes Dev. (2006)
- Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Berdnik, D., Knoblich, J.A. Curr. Biol. (2002)
- Phosphorylation of maskin by Aurora-A participates in the control of sequential protein synthesis during Xenopus laevis oocyte maturation. Pascreau, G., Delcros, J.G., Cremet, J.Y., Prigent, C., Arlot-Bonnemains, Y. J. Biol. Chem. (2005)
- The Aurora kinases: role in cell transformation and tumorigenesis. Katayama, H., Brinkley, W.R., Sen, S. Cancer Metastasis Rev. (2003)
- Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Stenoien, D.L., Sen, S., Mancini, M.A., Brinkley, B.R. Cell Motil. Cytoskeleton (2003)
- Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. Giet, R., McLean, D., Descamps, S., Lee, M.J., Raff, J.W., Prigent, C., Glover, D.M. J. Cell Biol. (2002)
- Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. Marumoto, T., Honda, S., Hara, T., Nitta, M., Hirota, T., Kohmura, E., Saya, H. J. Biol. Chem. (2003)
- A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Schumacher, J.M., Ashcroft, N., Donovan, P.J., Golden, A. Development (1998)
- Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells. Terada, Y., Uetake, Y., Kuriyama, R. J. Cell Biol. (2003)
- Polo kinase and progression through M phase in Drosophila: a perspective from the spindle poles. Glover, D.M. Oncogene (2005)