Gene Review:
IPL1 - aurora kinase
Saccharomyces cerevisiae S288c
Synonyms:
Aurora kinase, Increase-in-ploidy protein 1, Spindle assembly checkpoint kinase, YPL209C
- A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Sandall, S., Severin, F., McLeod, I.X., Yates, J.R., Oegema, K., Hyman, A., Desai, A. Cell (2006)
- The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation. Zhang, K., Lin, W., Latham, J.A., Riefler, G.M., Schumacher, J.M., Chan, C., Tatchell, K., Hawke, D.H., Kobayashi, R., Dent, S.Y. Cell (2005)
- Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Tanaka, T.U., Rachidi, N., Janke, C., Pereira, G., Galova, M., Schiebel, E., Stark, M.J., Nasmyth, K. Cell (2002)
- The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Biggins, S., Severin, F.F., Bhalla, N., Sassoon, I., Hyman, A.A., Murray, A.W. Genes Dev. (1999)
- Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1. Kimura, M., Matsuda, Y., Yoshioka, T., Sumi, N., Okano, Y. Cytogenet. Cell Genet. (1998)
- A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. Bischoff, J.R., Anderson, L., Zhu, Y., Mossie, K., Ng, L., Souza, B., Schryver, B., Flanagan, P., Clairvoyant, F., Ginther, C., Chan, C.S., Novotny, M., Slamon, D.J., Plowman, G.D. EMBO J. (1998)
- Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. Kimura, M., Kotani, S., Hattori, T., Sumi, N., Yoshioka, T., Todokoro, K., Okano, Y. J. Biol. Chem. (1997)
- Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation. Francisco, L., Wang, W., Chan, C.S. Mol. Cell. Biol. (1994)
- Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies. Ohashi, S., Sakashita, G., Ban, R., Nagasawa, M., Matsuzaki, H., Murata, Y., Taniguchi, H., Shima, H., Furukawa, K., Urano, T. Oncogene (2006)
- Characterization of plant Aurora kinases during mitosis. Kawabe, A., Matsunaga, S., Nakagawa, K., Kurihara, D., Yoneda, A., Hasezawa, S., Uchiyama, S., Fukui, K. Plant Mol. Biol. (2005)
- An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Pinsky, B.A., Tatsutani, S.Y., Collins, K.A., Biggins, S. Dev. Cell (2003)
- Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cheeseman, I.M., Anderson, S., Jwa, M., Green, E.M., Kang, J., Yates, J.R., Chan, C.S., Drubin, D.G., Barnes, G. Cell (2002)
- Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Pinsky, B.A., Kotwaliwale, C.V., Tatsutani, S.Y., Breed, C.A., Biggins, S. Mol. Cell. Biol. (2006)
- Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation. Kang, J., Cheeseman, I.M., Kallstrom, G., Velmurugan, S., Barnes, G., Chan, C.S. J. Cell Biol. (2001)
- The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Li, Y., Bachant, J., Alcasabas, A.A., Wang, Y., Qin, J., Elledge, S.J. Genes Dev. (2002)
- The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Biggins, S., Murray, A.W. Genes Dev. (2001)
- The S. pombe Cdc14-like phosphatase Clp1p regulates chromosome biorientation and interacts with Aurora kinase. Trautmann, S., Rajagopalan, S., McCollum, D. Dev. Cell (2004)
- Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Chan, C.S., Botstein, D. Genetics (1993)