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Gene Review

MFI2  -  antigen p97 (melanoma associated)...

Homo sapiens

Synonyms: CD228, FLJ38863, MAP97, MGC4856, MTF1, ...
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Disease relevance of MFI2


High impact information on MFI2


Biological context of MFI2


Anatomical context of MFI2


Associations of MFI2 with chemical compounds


Analytical, diagnostic and therapeutic context of MFI2


  1. Transfected mouse melanoma lines that express various levels of human melanoma-associated antigen p97. Estin, C.D., Stevenson, U., Kahn, M., Hellström, I., Hellström, K.E. J. Natl. Cancer Inst. (1989) [Pubmed]
  2. Cadmium-mediated activation of the metal response element in human neuroblastoma cells lacking functional metal response element-binding transcription factor-1. Chu, W.A., Moehlenkamp, J.D., Bittel, D., Andrews, G.K., Johnson, J.A. J. Biol. Chem. (1999) [Pubmed]
  3. The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark--from iron metabolism to tumorigenesis. Suryo Rahmanto, Y., Dunn, L.L., Richardson, D.R. Oncogene (2007) [Pubmed]
  4. Assignment of the gene for human melanoma-associated antigen p97 to chromosome 3. Plowman, G.D., Brown, J.P., Enns, C.A., Schröder, J., Nikinmaa, B., Sussman, H.H., Hellström, K.E., Hellström, I. Nature (1983) [Pubmed]
  5. Human melanoma-associated antigen p97 is structurally and functionally related to transferrin. Brown, J.P., Hewick, R.M., Hellström, I., Hellström, K.E., Doolittle, R.F., Dreyer, W.J. Nature (1982) [Pubmed]
  6. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1. Palmiter, R.D. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  7. Ribosomal protein S25 mRNA partners with MTF-1 and La to provide a p53-mediated mechanism for survival or death. Adilakshmi, T., Laine, R.O. J. Biol. Chem. (2002) [Pubmed]
  8. Differential sensitivity of zinc finger transcription factors MTF-1, Sp1 and Krox-20 to CpG methylation of their binding sites. Radtke, F., Hug, M., Georgiev, O., Matsuo, K., Schaffner, W. Biol. Chem. Hoppe-Seyler (1996) [Pubmed]
  9. Forearm blood flow responses to neuropeptide Y, noradrenaline and adenosine 5'-triphosphate in hypertensive and normotensive subjects. Nilsson, T., Hrafnkelsdóttir, T., Edvinsson, L., Jern, S., Erlinge, D., Wall, U. Blood Press. (2000) [Pubmed]
  10. Role of metal-responsive transcription factor-1 (MTF-1) in EGF-dependent DNA synthesis in primary hepatocytes. Kimura, T., Itoh, N., Sone, T., Kondoh, M., Tanaka, K., Isobe, M. J. Cell. Biochem. (2006) [Pubmed]
  11. Development of a bispecific monoclonal antibody against a gallium-67 chelate and the human melanoma-associated antigen p97 for potential use in pretargeted immunoscintigraphy. Somasundaram, C., Matzku, S., Schuhmacher, J., Zöller, M. Cancer Immunol. Immunother. (1993) [Pubmed]
  12. Detection of melanoma cells in bone marrow using monoclonal antibodies. A comparison of fluorescence activated cell sorting (FACS) and conventional immunofluorescence (IF). Dantas, M.E., Brown, J.P., Thomas, M.R., Robinson, W.A., Glode, L.M. Cancer (1983) [Pubmed]
  13. Localization of melanoma-associated antigen p97 in cultured human melanoma, as visualized by light and electron microscopy. Tilgen, W., Hellström, I., Engstner, M., Garrigues, H.J., Riehl, R., Hellström, K.E. J. Invest. Dermatol. (1983) [Pubmed]
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