Gene Review:
Ctla4 - cytotoxic T-lymphocyte-associated protein 4
Rattus norvegicus
Synonyms:
CTLA-4, Cd152, sCTLA4
- Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4. Im, S.H., Barchan, D., Maiti, P.K., Fuchs, S., Souroujon, M.C. J. Immunol. (2001)
- Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia. De Greef, K.E., Ysebaert, D.K., Dauwe, S., Persy, V., Vercauteren, S.R., Mey, D., De Broe, M.E. Kidney Int. (2001)
- CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis. Reynolds, J., Tam, F.W., Chandraker, A., Smith, J., Karkar, A.M., Cross, J., Peach, R., Sayegh, M.H., Pusey, C.D. J. Clin. Invest. (2000)
- Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection. Utans, U., Arceci, R.J., Yamashita, Y., Russell, M.E. J. Clin. Invest. (1995)
- Mechanisms of targeting CD28 by a signaling monoclonal antibody in acute and chronic allograft rejection. Dong, V.M., Yuan, X., Coito, A.J., Waaga, A.M., Sayegh, M.H., Chandraker, A. Transplantation (2002)
- CTLA4IgG treatment induces long-term acceptance of rat small bowel allografts. Tarumi, K., Murakami, M., Yagihashi, A., Nakagawa, I., Hirata, K., Uede, T. Transplantation (1999)
- Nucleotide sequence of the ACI rat CTLA-4 molecule. Oaks, M.K., Penwell, R.T., Tector, A.J. Immunogenetics (1996)
- Suppression of experimental myasthenia gravis, a B cell-mediated autoimmune disease, by blockade of IL-18. Im, S.H., Barchan, D., Maiti, P.K., Raveh, L., Souroujon, M.C., Fuchs, S. FASEB J. (2001)
- Local or short-term systemic costimulatory molecule blockade prolongs rat corneal allograft survival. Thiel, M.A., Steiger, J.U., O'Connell, P.J., Lehnert, A.M., Coster, D.J., Williams, K.A. Clin. Experiment. Ophthalmol. (2005)
- Soluble CTLA4Ig modifies parameters of acute inflammation in rat lung allograft rejection without altering lymphocytic infiltration or transcription of key cytokines. Matsumura, Y., Zuo, X.J., Prehn, J., Linsley, P.S., Marchevsky, A., Kass, R.M., Matloff, J.M., Jordan, S.C. Transplantation (1995)
- Donor dendritic cells and recipient Kupffer cells in the induction of donor-specific immune hyporesponsiveness. Nakagawa, K., Matsuno, T., Iwagaki, H., Morimoto, Y., Fujiwara, T., Sadamori, H., Inagaki, M., Urushihara, N., Yagi, T., Tanaka, N. J. Int. Med. Res. (2001)
- Liver as an ideal target for gene therapy: expression of CTLA4Ig by retroviral gene transfer. Cheung, S.T., Tsui, T.Y., Wang, W.L., Yang, Z.F., Wong, S.Y., Ip, Y.C., Luk, J., Fan, S.T. J. Gastroenterol. Hepatol. (2002)
- Adenovirus-mediated CTLA4 immunoglobulin G gene therapy in cardiac xenotransplantation. Watanabe, T., Miyatake, T., Kumamoto, H., Mafune, N., Kubota, S., Okamoto, H., Murashita, T., Uede, T., Yasuda, K. Transplant. Proc. (2004)