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Gene Review

Pllp  -  plasmolipin

Rattus norvegicus

Synonyms: Plasma membrane proteolipid, Plasmolipin, Pmlp, Tm4sf11
 
 
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Disease relevance of Pllp

  • The identification in WMCVs of periaxolemmal-myelin proteins associated with ion and fluid movement, such as carbonic anhydrase, Na+,K+ ATPase, and the putative K+ channel protein plasmolipin, prompted us to examine the status of these vesicles in triethyl tin (TET)-induced myelin edema [1].
 

High impact information on Pllp

 

Biological context of Pllp

 

Anatomical context of Pllp

 

Other interactions of Pllp

  • Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS [4].
  • The enrichment observed for membrane-bound carbonic anhydrase is unique since other periaxolemmal proteins such as CNPase and plasmolipin are only present in equal amounts in periaxolemmal-myelin fractions and WMCVs [1].
 

Analytical, diagnostic and therapeutic context of Pllp

References

  1. Identification of membrane-bound carbonic anhydrase in white matter coated vesicles: the fate of carbonic anhydrase and other white matter coated vesicle proteins in triethyl tin-induced leukoencephalopathy. Sapirstein, V.S., Durrie, R., Nolan, C.E., Marks, N. J. Neurosci. Res. (1993) [Pubmed]
  2. Proteolipid plasmolipin: localization in polarized cells, regulated expression and lipid raft association in CNS and PNS myelin. Bosse, F., Hasse, B., Pippirs, U., Greiner-Petter, R., Müller, H.W. J. Neurochem. (2003) [Pubmed]
  3. Expression of a plasma membrane proteolipid during differentiation of neuronal and glial cells in primary culture. Shea, T.B., Fischer, I., Sapirstein, V. J. Neurochem. (1986) [Pubmed]
  4. Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS. Gillen, C., Gleichmann, M., Greiner-Petter, R., Zoidl, G., Kupfer, S., Bosse, F., Auer, J., Müller, H.W. Eur. J. Neurosci. (1996) [Pubmed]
  5. Expression of plasmolipin in oligodendrocytes. Fischer, I., Cochary, E.F., Konola, J.T., Romano-Clark, G. J. Neurosci. Res. (1991) [Pubmed]
 
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