The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Pdzk1  -  PDZ domain containing 1

Rattus norvegicus

Synonyms: C-terminal-linking and modulating protein, Clamp, Dietary Pi-regulated RNA-1, Diphor-1, Diphor1, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Pdzk1


Biological context of Pdzk1


Anatomical context of Pdzk1


Associations of Pdzk1 with chemical compounds

  • One-half of the hemithyroidectomized rats (HTX) received no further treatment; in the other one-half of the HTX rats (Clamp), plasma TSH levels were maintained at levels comparable with those in sham-operated animals by initiating constant thyroid hormone replacement beginning at the time of hemithyroidectomy [6].

Other interactions of Pdzk1


  1. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Dong, H., O'Brien, R.J., Fung, E.T., Lanahan, A.A., Worley, P.F., Huganir, R.L. Nature (1997) [Pubmed]
  2. Activity-dependent dendritic spine structural plasticity is regulated by small GTPase Rap1 and its target AF-6. Xie, Z., Huganir, R.L., Penzes, P. Neuron (2005) [Pubmed]
  3. The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Penzes, P., Johnson, R.C., Sattler, R., Zhang, X., Huganir, R.L., Kambampati, V., Mains, R.E., Eipper, B.A. Neuron (2001) [Pubmed]
  4. GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. Ye, B., Liao, D., Zhang, X., Zhang, P., Dong, H., Huganir, R.L. Neuron (2000) [Pubmed]
  5. Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. Hasegawa, M., Cuenda, A., Spillantini, M.G., Thomas, G.M., Buée-Scherrer, V., Cohen, P., Goedert, M. J. Biol. Chem. (1999) [Pubmed]
  6. Compensatory changes in thyroid blood flow are only partially mediated by thyrotropin. Michalkiewicz, M., Connors, J.M., Huffman, L.J., Pietrzyk, Z., Hedge, G.A. Am. J. Physiol. (1991) [Pubmed]
  7. Identification of a new gene product (diphor-1) regulated by dietary phosphate. Custer, M., Spindler, B., Verrey, F., Murer, H., Biber, J. Am. J. Physiol. (1997) [Pubmed]
  8. The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons. Anzai, N., Deval, E., Schaefer, L., Friend, V., Lazdunski, M., Lingueglia, E. J. Biol. Chem. (2002) [Pubmed]
  9. Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury. Zhang, B., Tao, F., Liaw, W.J., Bredt, D.S., Johns, R.A., Tao, Y.X. Pain (2003) [Pubmed]
  10. The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signal. Hwang, J.I., Kim, H.S., Lee, J.R., Kim, E., Ryu, S.H., Suh, P.G. J. Biol. Chem. (2005) [Pubmed]
  11. High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons. Costigan, M., Samad, T.A., Allchorne, A., Lanoue, C., Tate, S., Woolf, C.J. Mol. Cell. Neurosci. (2003) [Pubmed]
  12. Critical postsynaptic density 95/disc large/zonula occludens-1 interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites. Piccini, A., Malinow, R. J. Neurosci. (2002) [Pubmed]
  13. The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation. Shi, S.H., Cheng, T., Jan, L.Y., Jan, Y.N. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  14. SAP97 interacts with Kv1.5 in heterologous expression systems. Murata, M., Buckett, P.D., Zhou, J., Brunner, M., Folco, E., Koren, G. Am. J. Physiol. Heart Circ. Physiol. (2001) [Pubmed]
WikiGenes - Universities