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Gene Review

Nob1  -  NIN1/RPN12 binding protein 1 homolog (S....

Mus musculus

Synonyms: 1700021I09Rik, ART-4, Nob1p, Psmd8bp1, RNA-binding protein NOB1
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Disease relevance of Nob1

  • Here we characterise its effects in a NZO x F1(SJLxNZO) backcross population raised on high-fat or standard diet, and describe its interaction with the obesity quantitative trait locus (QTL) Nob1 [1].
  • It seemed, however, to enhance the effect of Nob1 on body weight and that of Nob2 on serum insulin concentration [2].
  • The locus maps 40cM distal of the previously described obesity locus Nob1 in the vicinity of the marker D5Mit244 and in the vicinity of hypercholesterolemia QTL previously identified in the NZB, CAST, and C57BL/6J strains [3].

High impact information on Nob1


Anatomical context of Nob1


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