Gene Review:
ZIC1 - Zic family member 1
Homo sapiens
Synonyms:
ZIC, ZNF201, Zinc finger protein 201, Zinc finger protein ZIC 1, Zinc finger protein of the cerebellum 1
- Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation. Grinberg, I., Northrup, H., Ardinger, H., Prasad, C., Dobyns, W.B., Millen, K.J. Nat. Genet. (2004)
- Genes differentially expressed in medulloblastoma and fetal brain. Michiels, E.M., Oussoren, E., Van Groenigen, M., Pauws, E., Bossuyt, P.M., Voûte, P.A., Baas, F. Physiol. Genomics (1999)
- Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter. Salero, E., Pérez-Sen, R., Aruga, J., Giménez, C., Zafra, F. J. Biol. Chem. (2001)
- Cerebellar degeneration and autoimmunity to zinc-finger proteins of the cerebellum. Bataller, L., Wade, D.F., Fuller, G.N., Rosenfeld, M.R., Dalmau, J. Neurology (2002)
- Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation. Ebert, P.J., Timmer, J.R., Nakada, Y., Helms, A.W., Parab, P.B., Liu, Y., Hunsaker, T.L., Johnson, J.E. Development (2003)
- Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. Mizugishi, K., Aruga, J., Nakata, K., Mikoshiba, K. J. Biol. Chem. (2001)
- Identification of a BMP inhibitor-responsive promoter module required for expression of the early neural gene zic1. Tropepe, V., Li, S., Dickinson, A., Gamse, J.T., Sive, H.L. Dev. Biol. (2006)
- Characterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction. Borras, A.M., Strominger, J.L., Speck, S.H. J. Virol. (1996)
- Joubert syndrome: a haplotype segregation strategy and exclusion of the zinc finger protein of cerebellum 1 (ZIC1) gene. Bennett, C.L., Parisi, M.A., Eckert, M.L., Huynh, H.M., Chance, P.F., Glass, I.A. Am. J. Med. Genet. A (2004)
- Investigation of downstream target genes of PAX3c, PAX3e and PAX3g isoforms in melanocytes by microarray analysis. Wang, Q., Kumar, S., Mitsios, N., Slevin, M., Kumar, P. Int. J. Cancer (2007)
- The zic1 gene is an activator of Wnt signaling. Merzdorf, C.S., Sive, H.L. Int. J. Dev. Biol. (2006)
- Binding of the ubiquitous cellular transcription factors Sp1 and Sp3 to the ZI domains in the Epstein-Barr virus lytic switch BZLF1 gene promoter. Liu, S., Borras, A.M., Liu, P., Suske, G., Speck, S.H. Virology (1997)
- Genetic variants in ZIC1, ZIC2, and ZIC3 are not major risk factors for neural tube defects in humans. Klootwijk, R., Groenen, P., Schijvenaars, M., Hol, F., Hamel, B., Straatman, H., Steegers-Theunissen, R., Mariman, E., Franke, B. Am. J. Med. Genet. A (2004)
- Genomic structure of the gene encoding the human GLI-related, Krüppel-like zinc finger protein GLIS2. Zhang, F., Jetten, A.M. Gene (2001)
- Cerebellar vermis aplasia: patient report and exclusion of the candidate genes EN2 and ZIC1. Titomanlio, L., Pierri, N.B., Romano, A., Imperati, F., Borrelli, M., Barletta, V., Diano, A.A., Castaldo, I., Santoro, L., Del Giudice, E. Am. J. Med. Genet. A (2005)