Gene Review:
CAS1 - cycloartenol synthase
Arabidopsis thaliana
Synonyms:
CYCLOARTENOL SYNTHASE 1, T4E14.16, T4E14_16, cycloartenol synthase 1
- Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase. Corey, E.J., Matsuda, S.P., Bartel, B. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase. Lodeiro, S., Schulz-Gasch, T., Matsuda, S.P. J. Am. Chem. Soc. (2005)
- Conversion of a plant oxidosqualene-cycloartenol synthase to an oxidosqualene-lanosterol cyclase by random mutagenesis. Wu, T.K., Griffin, J.H. Biochemistry (2002)
- Steric bulk at cycloartenol synthase position 481 influences cyclization and deprotonation. Matsuda, S.P., Darr, L.B., Hart, E.A., Herrera, J.B., McCann, K.E., Meyer, M.M., Pang, J., Schepmann, H.G. Org. Lett. (2000)
- Molecular cloning and characterization of a cDNA for Glycyrrhiza glabra cycloartenol synthase. Hayashi, H., Hiraoka, N., Ikeshiro, Y., Kushiro, T., Morita, M., Shibuya, M., Ebizuka, Y. Biol. Pharm. Bull. (2000)
- Molecular cloning of pea cDNA encoding cycloartenol synthase and its functional expression in yeast. Morita, M., Shibuya, M., Lee, M.S., Sankawa, U., Ebizuka, Y. Biol. Pharm. Bull. (1997)
- Two branches of the lupeol synthase gene in the molecular evolution of plant oxidosqualene cyclases. Shibuya, M., Zhang, H., Endo, A., Shishikura, K., Kushiro, T., Ebizuka, Y. Eur. J. Biochem. (1999)
- Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice. Hayashi, H., Huang, P., Kirakosyan, A., Inoue, K., Hiraoka, N., Ikeshiro, Y., Kushiro, T., Shibuya, M., Ebizuka, Y. Biol. Pharm. Bull. (2001)
- Zymomonas mobilis squalene-hopene cyclase gene (shc): cloning, DNA sequence analysis, and expression in Escherichia coli. Reipen, I.G., Poralla, K., Sahm, H., Sprenger, G.A. Microbiology (Reading, Engl.) (1995)
- Cloning and characterization of the Arabidopsis thaliana lupeol synthase gene. Herrera, J.B., Bartel, B., Wilson, W.K., Matsuda, S.P. Phytochemistry (1998)