Gene Review:
PEX5 - Pex5p
Saccharomyces cerevisiae S288c
Synonyms:
PAS10, PTS1 receptor, PTS1R, Peroxin-5, Peroxisomal protein PAS10, ...
- Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways. Albertini, M., Rehling, P., Erdmann, R., Girzalsky, W., Kiel, J.A., Veenhuis, M., Kunau, W.H. Cell (1997)
- Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders. Reuber, B.E., Germain-Lee, E., Collins, C.S., Morrell, J.C., Ameritunga, R., Moser, H.W., Valle, D., Gould, S.J. Nat. Genet. (1997)
- Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders. Dodt, G., Braverman, N., Wong, C., Moser, A., Moser, H.W., Watkins, P., Valle, D., Gould, S.J. Nat. Genet. (1995)
- Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery. Agne, B., Meindl, N.M., Niederhoff, K., Einwächter, H., Rehling, P., Sickmann, A., Meyer, H.E., Girzalsky, W., Kunau, W.H. Mol. Cell (2003)
- Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain. Douangamath, A., Filipp, F.V., Klein, A.T., Barnett, P., Zou, P., Voorn-Brouwer, T., Vega, M.C., Mayans, O.M., Sattler, M., Distel, B., Wilmanns, M. Mol. Cell (2002)
- Functional similarity between the peroxisomal PTS2 receptor binding protein Pex18p and the N-terminal half of the PTS1 receptor Pex5p. Schäfer, A., Kerssen, D., Veenhuis, M., Kunau, W.H., Schliebs, W. Mol. Cell. Biol. (2004)
- Saccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner. Bottger, G., Barnett, P., Klein, A.T., Kragt, A., Tabak, H.F., Distel, B. Mol. Biol. Cell (2000)
- Pex8p, an intraperoxisomal peroxin of Saccharomyces cerevisiae required for protein transport into peroxisomes binds the PTS1 receptor pex5p. Rehling, P., Skaletz-Rorowski, A., Girzalsky, W., Voorn-Brouwer, T., Franse, M.M., Distel, B., Veenhuis, M., Kunau, W.H., Erdmann, R. J. Biol. Chem. (2000)
- The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells. Kragt, A., Voorn-Brouwer, T., van den Berg, M., Distel, B. J. Biol. Chem. (2005)
- Modification of the monomer composition of polyhydroxyalkanoate synthesized in Saccharomyces cerevisiae expressing variants of the beta-oxidation-associated multifunctional enzyme. Marchesini, S., Erard, N., Glumoff, T., Hiltunen, J.K., Poirier, Y. Appl. Environ. Microbiol. (2003)
- Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol. Platta, H.W., Grunau, S., Rosenkranz, K., Girzalsky, W., Erdmann, R. Nat. Cell Biol. (2005)
- Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants. Otera, H., Okumoto, K., Tateishi, K., Ikoma, Y., Matsuda, E., Nishimura, M., Tsukamoto, T., Osumi, T., Ohashi, K., Higuchi, O., Fujiki, Y. Mol. Cell. Biol. (1998)
- The plant PTS1 receptor: similarities and differences to its human and yeast counterparts. Wimmer, C., Schmid, M., Veenhuis, M., Gietl, C. Plant J. (1998)
- Motif refinement of the peroxisomal targeting signal 1 and evaluation of taxon-specific differences. Neuberger, G., Maurer-Stroh, S., Eisenhaber, B., Hartig, A., Eisenhaber, F. J. Mol. Biol. (2003)
- The difference in recognition of terminal tripeptides as peroxisomal targeting signal 1 between yeast and human is due to different affinities of their receptor Pex5p to the cognate signal and to residues adjacent to it. Lametschwandtner, G., Brocard, C., Fransen, M., Van Veldhoven, P., Berger, J., Hartig, A. J. Biol. Chem. (1998)
- Cloning of two splice variants of the rice PTS1 receptor, OsPex5pL and OsPex5pS, and their functional characterization using pex5-deficient yeast and Arabidopsis. Lee, J.R., Jang, H.H., Park, J.H., Jung, J.H., Lee, S.S., Park, S.K., Chi, Y.H., Moon, J.C., Lee, Y.M., Kim, S.Y., Kim, J.Y., Yun, D.J., Cho, M.J., Lee, K.O., Lee, S.Y. Plant J. (2006)
- Hansenula polymorpha Swi1p and Snf2p are essential for methanol utilisation. Ozimek, P., Lahtchev, K., Kiel, J.A., Veenhuis, M., van der Klei, I.J. FEMS Yeast Res. (2004)
- Obstruction of polyubiquitination affects PTS1 peroxisomal matrix protein import. Kiel, J.A., Otzen, M., Veenhuis, M., van der Klei, I.J. Biochim. Biophys. Acta (2005)
- The tetratricopeptide repeat domains of human, tobacco, and nematode PEX5 proteins are functionally interchangeable with the analogous native domain for peroxisomal import of PTS1-terminated proteins in yeast. Gurvitz, A., Wabnegger, L., Langer, S., Hamilton, B., Ruis, H., Hartig, A. Mol. Genet. Genomics (2001)
- Yeast Pex14p possesses two functionally distinct Pex5p and one Pex7p binding sites. Niederhoff, K., Meindl-Beinker, N.M., Kerssen, D., Perband, U., Schäfer, A., Schliebs, W., Kunau, W.H. J. Biol. Chem. (2005)
- Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p. Yang, X., Purdue, P.E., Lazarow, P.B. Eur. J. Cell Biol. (2001)
- PTS1-independent targeting of isocitrate lyase to peroxisomes requires the PTS1 receptor Pex5p. Parkes, J.A., Langer, S., Hartig, A., Baker, A. Mol. Membr. Biol. (2003)
- Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes. Gurvitz, A., Langer, S., Piskacek, M., Hamilton, B., Ruis, H., Hartig, A. Yeast (2000)
- Identification and characterization of the putative human peroxisomal C-terminal targeting signal import receptor. Fransen, M., Brees, C., Baumgart, E., Vanhooren, J.C., Baes, M., Mannaerts, G.P., Van Veldhoven, P.P. J. Biol. Chem. (1995)