Gene Review:
UFD1 - polyubiquitin-binding protein UFD1
Saccharomyces cerevisiae S288c
Synonyms:
PIP3, Polymerase-interacting protein 3, UB fusion protein 1, Ubiquitin fusion degradation protein 1, YGR048W
- The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis. Cao, K., Nakajima, R., Meyer, H.H., Zheng, Y. Cell (2003)
- PIP2 and PIP3: complex roles at the cell surface. Czech, M.P. Cell (2000)
- Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Hetzer, M., Meyer, H.H., Walther, T.C., Bilbao-Cortes, D., Warren, G., Mattaj, I.W. Nat. Cell Biol. (2001)
- Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. Ye, Y., Meyer, H.H., Rapoport, T.A. J. Cell Biol. (2003)
- Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites. Park, S., Isaacson, R., Kim, H.T., Silver, P.A., Wagner, G. Structure (Camb.) (2005)
- The Cdc48/p97-Ufd1-Npl4 complex: its potential role in coordinating cellular morphogenesis during the M-G1 transition. Cao, K., Zheng, Y. Cell Cycle (2004)
- Der1-mediated Preprotein Import into the Periplastid Compartment of Chromalveolates? Sommer, M.S., Gould, S.B., Lehmann, P., Gruber, A., Przyborski, J.M., Maier, U.G. Mol. Biol. Evol. (2007)
- The Uba2 and Ufd1 proteins of Saccharomyces cerevisiae interact with poly(A) polymerase and affect the polyadenylation activity of cell extracts. del Olmo, M., Mizrahi, N., Gross, S., Moore, C.L. Mol. Gen. Genet. (1997)
- Cordycepin in Schizosaccharomyces pombe: effects on the wild type and phenotypes of mutants resistant to the drug. Naula, N., Hilti, N., Schweingruber, A.M., Schweingruber, M.E. Curr. Genet. (2003)
- Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L). Botta, A., Tandoi, C., Fini, G., Calabrese, G., Dallapiccola, B., Novelli, G. Gene (2001)
- Valosin-containing Protein (p97) Is a Regulator of Endoplasmic Reticulum Stress and of the Degradation of N-End Rule and Ubiquitin-Fusion Degradation Pathway Substrates in Mammalian Cells. W??jcik, C., Rowicka, M., Kudlicki, A., Nowis, D., McConnell, E., Kujawa, M., Demartino, G.N. Mol. Biol. Cell (2006)
- Retrotranslocation of a viral A/B toxin from the yeast endoplasmic reticulum is independent of ubiquitination and ERAD. Heiligenstein, S., Eisfeld, K., Sendzik, T., Jimen??z-Becker, N., Breinig, F., Schmitt, M.J. EMBO J. (2006)
- HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Bays, N.W., Wilhovsky, S.K., Goradia, A., Hodgkiss-Harlow, K., Hampton, R.Y. Mol. Biol. Cell (2001)
- A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation. Medicherla, B., Kostova, Z., Schaefer, A., Wolf, D.H. EMBO Rep. (2004)
- A proteolytic pathway that recognizes ubiquitin as a degradation signal. Johnson, E.S., Ma, P.C., Ota, I.M., Varshavsky, A. J. Biol. Chem. (1995)
- Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage. Saeki, Y., Tayama, Y., Toh-e, A., Yokosawa, H. Biochem. Biophys. Res. Commun. (2004)