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Gene Review

IMP2'  -  Imp2'p

Saccharomyces cerevisiae S288c

Synonyms: IMP2, Sugar utilization regulatory protein IMP2, YIL154C
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Disease relevance of IMP2'

  • Yeast cells deficient in the transcriptional activator Imp2p are viable, but display marked hypersensitivity to a variety of oxidative agents [1].

High impact information on IMP2'


Biological context of IMP2'


Anatomical context of IMP2'

  • The negative phenotype cannot be scored in the presence of inhibitors of respiration and oxidative phosphorylation, indicating that the role of the mitochondria in the utilization of the above-mentioned carbon sources in imp2 mutants is not at the energetical level [3].

Associations of IMP2' with chemical compounds

  • Imp2p (Yil154c) is a transcriptional activator involved in glucose derepression of the maltose, galactose and raffinose utilization pathways and in resistance to thermal, oxidative or osmotic stress [2].
  • The IMP2 gene of Saccharomyces cerevisiae is involved in the nucleo-mitochondrial control of maltose, galactose and raffinose utilization as shown by the inability of imp2 mutants to grow on these carbon sources in respiratory-deficient conditions or in the presence of ethidium bromide and erythromycin [3].

Other interactions of IMP2'


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