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Gene Review

araB  -  L-ribulokinase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0064, JW0062
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Disease relevance of araB


High impact information on araB


Chemical compound and disease context of araB


Biological context of araB

  • Here we report that araA, araB and araD, whose inactivation leads to an Ara- phenotype, are the first three ORFs of a nine cistron transcriptional unit with a total length of 11 kb [9].

Associations of araB with chemical compounds

  • The physiological and enzymatic properties of these L-arabinose non-utilizing mutants suggest that L-arabinose resistance is due to forward mutations in at least 3 other genes, araA, araB and araC, blocking steps prior to L-ribulose 5-phosphate accumulation [10].


  1. Neutrophil microbicidal activity: screening bacterial mutants for survival after phagocytosis using quantitative PCR. Rosen, H., Lewis, P.J., Nitzel, C.M. Jpn. J. Infect. Dis. (2004) [Pubmed]
  2. Starvation-induced Mucts62-mediated coding sequence fusion: a role for ClpXP, Lon, RpoS and Crp. Lamrani, S., Ranquet, C., Gama, M.J., Nakai, H., Shapiro, J.A., Toussaint, A., Maenhaut-Michel, G. Mol. Microbiol. (1999) [Pubmed]
  3. High-level expression of M13 gene II protein from an inducible polycistronic messenger RNA. Johnston, S., Lee, J.H., Ray, D.S. Gene (1985) [Pubmed]
  4. Transaldolase/glucose-6-phosphate isomerase bifunctional enzyme and ribulokinase as factors to increase xylitol production from D-arabitol in Gluconobacter oxydans. Sugiyama, M., Suzuki, S., Tonouchi, N., Yokozeki, K. Biosci. Biotechnol. Biochem. (2003) [Pubmed]
  5. In vivo formation of gene fusions encoding hybrid beta-galactosidase proteins in one step with a transposable Mu-lac transducing phage. Casadaban, M.J., Chou, J. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  6. Nucleotide sequence of the 5' end of araBAD operon messenger RNA in Escherichia coli B/r. Lee, N., Carbon, J. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  7. DNA sequence of the araBAD-araC controlling region in Salmonella typhimurium LT2. Horwitz, A.H., Heffernan, L., Morandi, C., Lee, J.H., Timko, J., Wilcox, G. Gene (1981) [Pubmed]
  8. High-Level Gene Expression for Recombinant Penicillin Acylase Production Using the araB Promoter System in Escherichia coli. Narayanan, N., Xu, Y., Chou, C.P. Biotechnol. Prog. (2006) [Pubmed]
  9. The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Sá-Nogueira, I., Nogueira, T.V., Soares, S., de Lencastre, H. Microbiology (Reading, Engl.) (1997) [Pubmed]
  10. The L-arabinose-resistance test with Salmonella typhimurium strain SV3 selects forward mutations at several ara genes. Pueyo, C., Lopez-Barea, J. Mutat. Res. (1979) [Pubmed]
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