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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Activation Analysis

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Disease relevance of Activation Analysis


High impact information on Activation Analysis

  • Activation analysis of position 256 receptor mutants by Ang II position 8 analogues suggests that aromaticity of Phe8 and His256 side chains is crucial for receptor activation; however, a stacked rather than an amino-aromatic interaction appears to operate at this switch locus [2].
  • Activation analysis of AT1 receptor position 111 mutants by various Ang II position 4 analogues suggests that an amino-aromatic bonding interaction operates between the residue Asn111 of the AT1 receptor and Tyr4 of Ang II [2].
  • Trace element concentration in human brain. Activation analysis of cobalt, iron, rubidium, selenium, zinc, chromium, silver, cesium, antimony and scandium [3].
  • These methods include total body potassium by whole-body counting of endogenous 40K; total body calcium (TBCa), sodium and chloride by in vivo neutron activation analysis and total body phosphorus (TBP) and nitrogen (TBN) by photon activation analysis [4].
  • The extent of penetration of carboplatin through tumour nodules has not yet been assessed but tumour nodules are being processed for nuclear activation analysis [5].

Biological context of Activation Analysis


Anatomical context of Activation Analysis

  • ECW volumes were determined from NaBr dilution, total body chlorine (TBCl) by delayed gamma-neutron activation analysis, total body water (TBW) by tritium dilution combined with total body potassium (TBK) by whole body 40K counting, and radioactive sulfate dilution (35SO4) [8].

Associations of Activation Analysis with chemical compounds


Gene context of Activation Analysis

  • Our activation analysis revealed that the maximal activation of the RicGAD occurred in the presence of both Ca(2+) and calmodulin [13].
  • The aim of this study was to evaluate total Co content in alluvial soils of Delta in Egypt using the delayed neturen activation analysis technique (DNAA) [14].
  • For this purpose, the chemical compositions of fresh graphite samples and different types of concrete have been determined by activation analysis in the research reactors OSIRIS and ORPHEE of CEA Saclay (France) [15].

Analytical, diagnostic and therapeutic context of Activation Analysis


  1. Activation analyses of authenticated hairs of Napoleon Bonaparte confirm arsenic poisoning. Weider, B., Fournier, J.H. The American journal of forensic medicine and pathology : official publication of the National Association of Medical Examiners. (1999) [Pubmed]
  2. Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor. Miura, S., Feng, Y.H., Husain, A., Karnik, S.S. J. Biol. Chem. (1999) [Pubmed]
  3. Trace element concentration in human brain. Activation analysis of cobalt, iron, rubidium, selenium, zinc, chromium, silver, cesium, antimony and scandium. Höck, A., Demmel, U., Schicha, H., Kasperek, K., Feinendegen, L.E. Brain (1975) [Pubmed]
  4. In vivo animal models of body composition in aging. Yasumura, S., Jones, K., Spanne, P., Schidlovsky, G., Wielopolski, L., Ren, X., Glaros, D., Xatzikonstantinou, Y. J. Nutr. (1993) [Pubmed]
  5. Phase I study and pharmacokinetics of intraperitoneal carboplatin. McVie, J.G., ten Bokkel Huinink, W., Dubbelman, R., Franklin, H., van der Vijgh, W., Klein, I. Cancer Treat. Rev. (1985) [Pubmed]
  6. Proliferation and apoptosis in a neuroblastoma cell line exposed to 900 MHz modulated radiofrequency field. Merola, P., Marino, C., Lovisolo, G.A., Pinto, R., Laconi, C., Negroni, A. Bioelectromagnetics. (2006) [Pubmed]
  7. Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy. Podewski, E.K., Hilfiker-Kleiner, D., Hilfiker, A., Morawietz, H., Lichtenberg, A., Wollert, K.C., Drexler, H. Circulation (2003) [Pubmed]
  8. Extracellular water: sodium bromide dilution estimates compared with other markers in patients with acquired immunodeficiency syndrome. Kim, J., Wang, Z., Gallagher, D., Kotler, D.P., Ma, K., Heymsfield, S.B. JPEN. Journal of parenteral and enteral nutrition. (1999) [Pubmed]
  9. Proton activation analysis of stable isotopes for a molybdenum biokinetics study in humans. Cantone, M.C., de Bartolo, D., Gambarini, G., Giussani, A., Ottolenghi, A., Pirola, L., Hansen, C., Roth, P., Werner, E. Medical physics. (1995) [Pubmed]
  10. Oxygen determination in calcium fluoride by deuteron activation analysis. Sastri, C.S., Blondiaux, G., Hoffmann, P., Ortner, H.M., Petri, H. Fresenius' journal of analytical chemistry. (2000) [Pubmed]
  11. Assay of antimonial compounds by activation analysis: its use in monitoring the clearance of free and liposomally-entrapped sodium stibogluconate by isolated perfused rat liver. Smith, J.E., Minski, M.J., Rao, L.S. Ann. Trop. Med. Parasitol. (1986) [Pubmed]
  12. Thromboxane A2 does not contribute to arrhythmogenesis during evolving canine myocardial infarction. Kramer, J.B., Davis, A.G., Dean, R., McCluskey, E.R., Needleman, P., Corr, P.B. J. Cardiovasc. Pharmacol. (1985) [Pubmed]
  13. Cloning and characterization of a rice cDNA encoding glutamate decarboxylase. Oh, S.H., Choi, W.G., Lee, I.T., Yun, S.J. J. Biochem. Mol. Biol. (2005) [Pubmed]
  14. Cobalt in alluvial Egyptian soils as affected by industrial activities. Zohny, E.A. Journal of environmental sciences (China). (2002) [Pubmed]
  15. Activation analysis of concrete and graphite in the experimental reactor RUS. Cometto, M., Ridikas, D., Aubert, M.C., Damoy, F., Ancius, D. Radiation protection dosimetry. (2005) [Pubmed]
  16. Studies of cadmium uptake in bone and its environmental distribution. Krishnan, S.S., Lui, S.M., Jervis, R.E., Harrison, J.E. Biological trace element research. (1990) [Pubmed]
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