Disease relevance of Activation Analysis

• In 1960, activation analyses at the Harwell Nuclear Research Laboratory of the University of Glascow, London of authenticated hairs of Napoleon Bonaparte taken immediately after his death confirmed Napoleon's chronic arsenic poisoning on the island of St [1].

High impact information on Activation Analysis

• Activation analysis of position 256 receptor mutants by Ang II position 8 analogues suggests that aromaticity of Phe8 and His256 side chains is crucial for receptor activation; however, a stacked rather than an amino-aromatic interaction appears to operate at this switch locus [2].
• Activation analysis of AT1 receptor position 111 mutants by various Ang II position 4 analogues suggests that an amino-aromatic bonding interaction operates between the residue Asn111 of the AT1 receptor and Tyr4 of Ang II [2].
• Trace element concentration in human brain. Activation analysis of cobalt, iron, rubidium, selenium, zinc, chromium, silver, cesium, antimony and scandium [3].
• These methods include total body potassium by whole-body counting of endogenous 40K; total body calcium (TBCa), sodium and chloride by in vivo neutron activation analysis and total body phosphorus (TBP) and nitrogen (TBN) by photon activation analysis [4].
• The extent of penetration of carboplatin through tumour nodules has not yet been assessed but tumour nodules are being processed for nuclear activation analysis [5].

Biological context of Activation Analysis

• Apoptosis was evaluated by caspase activation analysis and by molecular detection of Poly (ADP-ribose) polimerase (PARP) cleavage [6].
• METHODS AND RESULTS: We performed a comprehensive expression and activation analysis of IL-6-related cytokines, receptors, signal transducers, and signal transduction inhibitors in left ventricular (LV) myocardia from patients with DCM (n=10) and non-failing (NF) donor hearts (n=5) [7].

Anatomical context of Activation Analysis

• ECW volumes were determined from NaBr dilution, total body chlorine (TBCl) by delayed gamma-neutron activation analysis, total body water (TBW) by tritium dilution combined with total body potassium (TBK) by whole body 40K counting, and radioactive sulfate dilution (35SO4) [8].

Associations of Activation Analysis with chemical compounds

• Proton activation analysis of stable isotopes for a molybdenum biokinetics study in humans [9].
• Oxygen determination in calcium fluoride by deuteron activation analysis [10].
• Oxygen at trace level in calcium fluoride was determined by instrumental deuteron activation analysis based on the 16O(d,n)17F reaction [10].
• Assay of antimonial compounds by activation analysis: its use in monitoring the clearance of free and liposomally-entrapped sodium stibogluconate by isolated perfused rat liver [11].
• In the second group, (n = 5) regional conduction velocity was assessed using detailed three-dimensional activation analysis from 232 simultaneous intramyocardial sites, and no change was induced by the thromboxane synthetase inhibitor OKY-1581 in either normal or infarcted myocardial zones during sinus rhythm or with pacing [12].

Gene context of Activation Analysis

• Our activation analysis revealed that the maximal activation of the RicGAD occurred in the presence of both Ca(2+) and calmodulin [13].
• The aim of this study was to evaluate total Co content in alluvial soils of Delta in Egypt using the delayed neturen activation analysis technique (DNAA) [14].
• For this purpose, the chemical compositions of fresh graphite samples and different types of concrete have been determined by activation analysis in the research reactors OSIRIS and ORPHEE of CEA Saclay (France) [15].

Analytical, diagnostic and therapeutic context of Activation Analysis

• In addition, cadmium levels have been estimated in a variety of sources, e.g., foodstuff, fertilizer, and sewage sludge, using neutron and proton activation analyses and atomic absorption spectrophotometry [16].

References