Disease relevance of CALCIUM FLUORIDE

• Radon-progeny exposure and lung cancer risk in a cohort of Newfoundland fluorspar miners [1].
• The mechanism of sudden cardiac death following acute fluoride intoxication has been thought to result from profound hypocalcemia produced by the precipitation of calcium fluoride salts [2].
• Coronary heart disease mortality among Newfoundland fluorspar miners [3].
• The authors suggest that the emphysematous lesion seen in autopsy material of pneumoconiosis of fluorite mine workers may be caused by calcium fluorite and silica [4].
• Animal experiments showed that calcium fluorite can induce only a foreign body reaction in the lungs; the fibrous nodular lesions induced by the fluorite mine dust are due mainly to its silica component [4].

High impact information on CALCIUM FLUORIDE

• METHODS: Tissue sections from native and trypsin-digested bovine nasal cartilage (BNC) and from engineered cartilage, generated by chick sternal chondrocytes grown in a hollow fiber bioreactor, were placed either on calcium fluoride windows for FTIR analysis or gelatinized microscope slides for histologic analysis [5].
• 19F and (119)Sn MAS NMR spectroscopy have been used to investigate the fluoride ion conductor, BaSnF(4), a member of the MSnF(4) family of fluorite-related anionic conductors containing double layers of Sn(2+) and M(2+) cations [6].
• In this study we investigated the possibility of the formation of a calcium fluoride surface film on the new bone matrix in patients undergoing fluoride treatment for osteoporosis [7].
• Our results show that 45Ca uptake is activated by NaF in vascular smooth muscle cells by nonspecific accumulation of calcium-fluoride complexes and is not related to modification of Gps [8].
• It is suggested that a reduced calcium fluoride dissolution rate, in the presence of phosphate, can account for the relatively slow loss of calcium fluoride from dental enamel observed in recent clinical studies [9].

Biological context of CALCIUM FLUORIDE

• The constant composition kinetics method enables the rates of remineralization to be precisely determined, and the possibility of the direct growth of fluorapatite on calcium fluoride crystals in calcium phosphate solutions of low supersaturation has also been examined [10].
• Hydrolysis of dicalcium phosphate dihydrate in the presence or absence of calcium fluoride [11].
• Submicrometer mineralized spheres composed of calcium fluoride or silica are common in carbonate hot spring deposits [12].
• The pathogenicity of dust from a fluorite mine [4].
• There was poor correlation between intensity of environmental exposure to fluorspar and postshift fluoride concentration in the urine [13].

Anatomical context of CALCIUM FLUORIDE

• It was demonstrated that either silica or the mixed dust of a fluorite mine can stimulate pulmonary alveolar macrophages (PAMs) to release fibrogenetic factors in vitro, but calcium fluorite cannot [4].
• Special attention is given to mineral components in enamel, dentin, and calculus, and to calcium fluoride formed in/on enamel [14].

Associations of CALCIUM FLUORIDE with other chemical compounds

• Oxygen determination in calcium fluoride by deuteron activation analysis [15].
• When solutions A and B were combined, the free F ions produced by hydrolysis of fluorosilicate caused precipitation of calcium fluoride during the 1-min application time [16].
• According to the composition (CaF(2)>97%, SiO(2)<1%), the synthetic calcium fluoride from the crystallization process in a FBR is able to be recycled as raw material for the manufacture of hydrofluoric acid leading to a reduction of raw materials consumption [17].
• In a second series of experiments, the effect of extracellular calcium on concentration was correlated with the intracellular concentration of free calcium using the calcium fluoride FURA-2 and surface spectrofluorometry [18].
• Two in vivo experiments were performed, concerning (1) the kinetics of the acquisition of calcium fluoride on enamel during daily rinses with a solution of 0.023% F as sodium fluoride, and (2) the loss of calcium fluoride from enamel slabs which had been topically treated with a neutral solution containing 0.9% F as sodium fluoride [19].

Gene context of CALCIUM FLUORIDE

• In an approach to determine the ultrastructure of the casein phosphopeptide-amorphous calcium fluoride phosphate complexes, we have studied the structure of the predominant peptide alpha(S1)-CN(59-79) bound to ACFP using nuclear magnetic resonance (NMR) spectroscopy and X-ray diffraction [20].
• Influence of glass composition on the properties of glass polyalkenoate cements. Part III: influence of fluorite content [21].
• Parameters that were measured included rat caries, number of cariogenic bacteria in plaque, salivary parameters including flow rate, buffering capacity, total protein, lysozyme and amylase content, and composition of test foods including protein, fat, phosphorus, calcium, fluoride, galactose, glucose, total reducing sugar, sucrose, and starch [22].
• PURPOSE: To evaluate the effects for cytotoxicity of two dentifrices: a toothpaste commercially available (Crest Extra-Whitening toothpaste) and a new experimental toothpaste based on a mixture of ion-exchange resins (named NMTD) that supplies calcium, fluoride, phosphate and zinc ions [23].
• The absorption and the fluorescence spectra of Pr3+ ion doped in aluminum, barium, calcium fluoride (ABCF) glass have been studied [24].

Analytical, diagnostic and therapeutic context of CALCIUM FLUORIDE

• A cohort study of the mortality experience (1950-1984) of 1,772 Newfoundland underground fluorspar miners occupationally exposed to high levels of radon daughters (mean dose = 382.8 working levels months) has been conducted [25].
• Isoelectric point of fluorite by direct force measurements using atomic force microscopy [26].
• Fabrication of calcium fluoride capillary electrophoresis microdevices for on-chip infrared detection [27].
• The refractive indices of synthetic calcium fluoride for 69 wavelengths from 138 nm in the deep ultraviolet to 2326 nm in the near infrared were measured by the minimum-deviation method in a nitrogen environment [28].
• Calcium fluoride micro cells for synchrotron radiation circular dichroism spectroscopy [29].

References