Disease relevance of Administration, Buccal

• INTERVENTIONS: The dogs were intubated either with cuffed, noncoated endotracheal tubes or with endotracheal tubes having a novel antimicrobial silver hydrogel coating and were challenged with buccal administration of Pseudomonas aeruginosa [1].
• We report the case of a 62-year-old man with severe aortic stenosis and hypertrophic cardiomyopathy, who could not be weaned from cardiopulmonary bypass after aortic valve replacement until buccal administration of the calcium-blocking agent nifedipine led to achievement of adequate hemodynamics [2].

High impact information on Administration, Buccal

• We aimed to find out whether there are differences in efficacy and adverse events between buccal administration of liquid midazolam and rectal administration of liquid diazepam in the acute treatment of seizures [3].
• Half-life of peptide activity after buccal administration was 27 and 24 min measured with COOH-terminal and NH2-terminal RIA, respectively [4].
• The results of these studies demonstrate that buccal administration of prochlorperazine produces plasma concentrations more than twice as high as an oral tablet, with less than half the variability [5].
• The matrix composed of chitosan lactate and poloxamer 407 showed the best characteristics for buccal administration [6].
• Development of mucoadhesive patches for buccal administration of ibuprofen [7].

Biological context of Administration, Buccal

• Bioavailability of flurbiprofen following buccal administration [8].
• This article discusses 2 clinical studies conducted to characterize the single-dose and multiple-dose pharmacokinetics of prochlorperazine and its metabolites after buccal administration [5].

Associations of Administration, Buccal with chemical compounds

• To assess potential cardiac effects of nifedipine and beta-blocker interactions, 10 men receiving chronic beta-blocker therapy for angina underwent hemodynamic, electrophysiologic and left ventricular (LV) functional analyses at the time of cardiac catheterization before and after buccal administration of 10 mg of nifedipine [9].
• Development of polymer film dosage forms of lidocaine for buccal administration: II. Comparison of preparation methods [10].
• Absorption of clonazepam after intranasal and buccal administration [11].
• A solid dose form containing 50 mg of etomidate in sorbitol for buccal administration was prepared [12].
• The buccal administration of testosterone via the bioadhesive tablet allowed the maintenance of the plasma level at above 3 ng/ml for 15 to 24 h [13].

References