Disease relevance of Ossicular Prosthesis

• We conclude that PORP after pancuronium is a significant risk factor for hypoxemia [1].
• Hypoxemia and hypercapnia occurred more often in pancuronium patients with PORP than in those without PORP namely 60% vs. 10% (p<0.05) and 30% vs. 8% (p>0.05), respectively [1].
• Ossicular chain reconstruction: the TORP and PORP in chronic ear disease [2].

High impact information on Ossicular Prosthesis

• Main outcome measures were mean postoperative air-bone gap (ABG), proportion achieving ABG closure to <20 dB and <30 dB for group 1 and group 2 overall and when controlling for type of mastoid cavity created (open or closed) and the status of the stapes suprastructure (TORP vs. PORP OCR) [3].
• METHODS: Sixty-eight ossicular procedures using a titanium TORP (n = 30) or PORP (n = 38) were performed at a tertiary referral center between December 1999 and June 2002 [4].
• CONCLUSIONS: The titanium bell PORP showed improved postoperative results for the PTA-ABG and at 500 Hz and 1000 Hz [5].
• We defined PORP as a TOF-ratio <70%, hypoxemia as a postoperative SpO2 > or =5% below the pre-anesthestic level together with a postoperative SaO2 <93%, and hypercapnia as a PaCO2 > or =46 mm Hg [1].
• Among the 49 pancuronium and 27 vecuronium patients studied, the PORP rates were 20% in the pancuronium group and 7% in the vecuronium group (p>0.05) [1].

Biological context of Ossicular Prosthesis

• Otology and neurotology. TORP and PORP prosthesis: a cartilage-sandwich technique [6].

Anatomical context of Ossicular Prosthesis

• Middle ear reconstruction using cartilage and TORP and PORP [7].
• PATIENTS: All patients undergoing ossiculoplasty with the Dornhoffer HAPEX partial and total ossicular replacement prostheses (PORP and TORP) from February 1995 to May 1999 who had documented postoperative follow-up and no congenital atresia or stapes fixation [8].
• The present results indicate that hydroxyapatite is a suitable material for an ossicular prosthesis, although the incidence of extrusion is high when it is placed in contact with the tympanic membrane [9].
• Prosthesis extrusion, the cause of failure in less than 5% of 446 TORP and PORP operations, usually was the result of a mucous membrane or eustachian tube problem [10].

Associations of Ossicular Prosthesis with chemical compounds

• Plastipore had a lower air-bone gap than the titanium when a canal wall up operation was performed (17.8 vs. 23.9 dB) and tended toward a lower air-bone gap when a total ossicular prosthesis was needed (22 vs. 27 dB) (P <.07) [11].
• These favorable results led to phase II of the project, in which patients with surgically amendable mixed hearing losses were implanted with the target magnet incorporated within a hydroxyapatite ossicular prosthesis [12].

Gene context of Ossicular Prosthesis

• Success for TORP reconstruction was assessed as air-bone gap closure to within 30 dB and for PORP, to within 20 dB [2].

Analytical, diagnostic and therapeutic context of Ossicular Prosthesis

• OBJECTIVES/HYPOTHESIS: To study the preliminary hearing results in patients receiving a hybrid hydroxylapatite/titanium bell partial ossicular replacement prosthesis (PORP) and compare these with a cohort of patients receiving a HAPEX PORP [5].
• The difference between hydroxylapatite and control group success rates appears to be due to the poorer results of the hydroxylapatite PORP [13].
• Closure of the air-bone gap at this frequency to within 10 dB was achieved in 87% of type I tympanoplasties, 73% of type III (PORP), and 70% of type III (TORP) tympanoplasties [14].
• Use of autograft and homograft TORP and PORP in the reconstruction of the conductive system in the middle ear [15].

References