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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Otolaryngology

  • METHODS: A comprehensive literature search was performed for articles using intratympanic gentamicin as a sole treatment modality with reporting of results according to the American Academy of Otolaryngology Head and Neck Surgery (AAO-HNS) guidelines for Menière's disease [1].
  • Thirty-six children with nasal dermoid sinus cysts were treated in the Department Pediatric Otolaryngology, Armand Trousseau's Children's Hospital (Paris, France) between 1974 and 1994 [2].
  • In the Department of Otolaryngology at the University of Pittsburgh School of Medicine, cancer of the larynx is usually treated by primary surgery [3].
  • MATERIAL AND METHODS: Twenty-seven patients with chronic oroantral and oral fistula who underwent surgical correction in the Hacettepe University Faculty of Medicine Department of Otorhinolaryngology Head and Neck Surgery between 1968 and 2001 were reviewed retrospectively [4].
  • METHODS: Eighty-eight fresh cases of unilateral cholesteatoma and 33 fresh cases of bilateral cholesteatoma, which were operated on at Department of Otolaryngology, Hyogo College of Medicine, were examined in this study [5].

High impact information on Otolaryngology

  • Bárány began his career working in the otology clinic of Adam Politzer at the University of Vienna [6].
  • However, in the subgroup of patients undergoing otorhinolaryngology surgery, surgical site bleeding occurred in 18 of 171 (10.5%) patients on tenoxicam and one of 57 (1.8%) on placebo (P=0.026); of these, nine in the tenoxicam group and 0 in the placebo were classified as major (P=0.07) [7].
  • Biopsy specimens from Alaskan Native patients with nasopharyngeal carcinoma (NPC) and from other patients seen on the otolaryngology service were tested for Epstein-Barr virus-specific DNA and nuclear antigen (EBNA) [8].
  • METHODS: A retrospective chart review was conducted on all patients considered to have AIED by the Otolaryngology division physicians and on all patients positive for antibody testing to inner ear antigens from 1990 to 1999 [9].
  • Sketches of otohistory Part 12: The history of otology in traditional Chinese medicine [10].

Biological context of Otolaryngology


Anatomical context of Otolaryngology


Associations of Otolaryngology with chemical compounds

  • The use of the CO2 laser in otolaryngology: ten years of experience [19].
  • Fifty-one patients (41 male, 10 female), who were referred to Hacettepe University Faculty of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery with suspected OSAHS, between April 2003 and June 2004, were included in the study [20].
  • CONCLUSION: The clinical use of cocaine in otolaryngology has decreased significantly in the past 25 years as a result of discontinuation of use by physicians who had previously used cocaine and an increasing number of otolaryngologists who have never used it [21].
  • SETTING: Department of Otolaryngology, The Toronto Hospital, University of Toronto. PATIENTS: Sixteen patients were identified with well-documented histories, physical findings and laboratory investigations consistent with topical gentamicin-induced ototoxicity [22].
  • OBJECTIVE: To describe the clinical manifestations of latex allergy in otolaryngology patients [23].

Gene context of Otolaryngology

  • Genetic testing was completed on 1,294 persons with deafness referred to the Molecular Otolaryngology Research Laboratories to establish a diagnosis of DFNB1 [24].
  • The continued spread of MRSA will have tremendous impact on the practice of medicine and otolaryngology during the next decade and beyond [25].
  • Sketches of otohistory. Part 2: origins of otology in the British Isles: Wilde And Toynbee [26].
  • Allergic rhinitis and its impact on otorhinolaryngology [27].
  • SETTING: Collaborating otology practices in Pennsylvania, Michigan, and Indiana. PATIENTS: Sixty-three patients with rapidly progressive unilateral or bilateral sensorineural hearing loss of unknown cause suggestive of autoimmune sensorineural hearing loss [28].

Analytical, diagnostic and therapeutic context of Otolaryngology


  1. Intratympanic gentamicin for Menière's disease: a meta-analysis. Cohen-Kerem, R., Kisilevsky, V., Einarson, T.R., Kozer, E., Koren, G., Rutka, J.A. Laryngoscope (2004) [Pubmed]
  2. Nasal dermoid sinus cysts in children. Denoyelle, F., Ducroz, V., Roger, G., Garabedian, E.N. Laryngoscope (1997) [Pubmed]
  3. Management of the neck in cancer of the larynx. Myers, E.N., Fagan, J.F. The Annals of otology, rhinology, and laryngology. (1999) [Pubmed]
  4. Treatment of oroantral fistula:experience with 27 cases. Yilmaz, T., Suslu, A.E., Gursel, B. American journal of otolaryngology. (2003) [Pubmed]
  5. Bilateral cholesteatoma and habitual sniffing. Tsuji, K., Sone, M., Kakibuchi, M., Sakagami, M. Auris, nasus, larynx. (2002) [Pubmed]
  6. Robert Bárány and the controversy surrounding his discovery of the caloric reaction. Baloh, R.W. Neurology (2002) [Pubmed]
  7. Clinical tolerability of perioperative tenoxicam in 1001 patients--a prospective, controlled, double-blind, multi-centre study. Merry, A.F., Webster, C.S., Holland, R.L., Middleton, N.G., Schug, S.A., James, M., McGrath, K.A. Pain (2004) [Pubmed]
  8. Association of Epstein-Barr virus with nasopharyngeal carcinoma in Alaskan native patients: serum antibodies and tissue EBNA and DNA. Lanier, A.P., Bornkamm, G.W., Henle, W., Henle, G., Bender, T.R., Talbot, M.L., Dohan, P.H. Int. J. Cancer (1981) [Pubmed]
  9. Immune-mediated inner ear disease: 10-year experience. Broughton, S.S., Meyerhoff, W.E., Cohen, S.B. Semin. Arthritis Rheum. (2004) [Pubmed]
  10. Sketches of otohistory Part 12: The history of otology in traditional Chinese medicine. Kong, W.J., Hao, J., Schacht, J. Audiol. Neurootol. (2006) [Pubmed]
  11. Auditory evoked potentials during propofol anaesthesia in man. Chassard, D., Joubaud, A., Colson, A., Guiraud, M., Dubreuil, C., Banssillon, V. British journal of anaesthesia. (1989) [Pubmed]
  12. Intratympanic gentamycin therapy for Menière's disease placed by tubal catheter with systemic isosorbide. Yamazaki, T., Hayashi, M., Hayashi, N., Kozaki, H. Archives of oto-rhino-laryngology. (1988) [Pubmed]
  13. Pseudomonas cepacia: implications and control of epidemic nosocomial colonization. Martone, W.J., Osterman, C.A., Fisher, K.A., Wenzel, R.P. Rev. Infect. Dis. (1981) [Pubmed]
  14. Physics of light and lasers. Absten, G.T. Obstet. Gynecol. Clin. North Am. (1991) [Pubmed]
  15. Towards a computer-aided diagnosis system for vocal cord diseases. Verikas, A., Gelzinis, A., Bacauskiene, M., Uloza, V. Artificial intelligence in medicine. (2006) [Pubmed]
  16. The assessment of the risk of cross-infection with a multi-use nasal atomizer. Spraggs, P.D., Hanekom, W.H., Mochloulis, G., Joseph, T., Kelsey, M.C. J. Hosp. Infect. (1994) [Pubmed]
  17. The enlarged vestibular aqueduct syndrome (EVA syndrome). Belenky, W.M., Madgy, D.N., Leider, J.S., Becker, C.J., Hotaling, A.J. Ear, nose, & throat journal. (1993) [Pubmed]
  18. Hypercoagulability in otologic patients. Gold, S., Kamerer, D.B., Hirsch, B.E., Cass, S.P. American journal of otolaryngology. (1993) [Pubmed]
  19. The use of the CO2 laser in otolaryngology: ten years of experience. Andrews, A.H. Lasers in surgery and medicine. (1984) [Pubmed]
  20. Body fat composition: a predictive factor for obstructive sleep apnea. Oğretmenoğlu, O., Süslü, A.E., Yücel, O.T., Onerci, T.M., Sahin, A. Laryngoscope (2005) [Pubmed]
  21. Medicinal use of cocaine: a shifting paradigm over 25 years. Long, H., Greller, H., Mercurio-Zappala, M., Nelson, L.S., Hoffman, R.S. Laryngoscope (2004) [Pubmed]
  22. Ototoxicity of topical gentamicin preparations. Bath, A.P., Walsh, R.M., Bance, M.L., Rutka, J.A. Laryngoscope (1999) [Pubmed]
  23. Latex allergy: an update for the otolaryngologist. Kashima, M.L., Tunkel, D.E., Cummings, C.W. Arch. Otolaryngol. Head Neck Surg. (2001) [Pubmed]
  24. GJB2: the spectrum of deafness-causing allele variants and their phenotype. Azaiez, H., Chamberlin, G.P., Fischer, S.M., Welp, C.L., Prasad, S.D., Taggart, R.T., del Castillo, I., Van Camp, G., Smith, R.J. Hum. Mutat. (2004) [Pubmed]
  25. Methicillin-resistant Staphylococcus aureus (MRSA) in the practice of otolaryngology--an emerging community acquired organism? Collins, M., Tami, T.A. Current opinion in otolaryngology & head and neck surgery. (2003) [Pubmed]
  26. Sketches of otohistory. Part 2: origins of otology in the British Isles: Wilde And Toynbee. Hawkins, J.E. Audiol. Neurootol. (2004) [Pubmed]
  27. Allergic rhinitis and its impact on otorhinolaryngology. Hellings, P.W., Fokkens, W.J. Allergy (2006) [Pubmed]
  28. Corticosteroid response and supporting cell antibody in autoimmune hearing loss. Zeitoun, H., Beckman, J.G., Arts, H.A., Lansford, C.D., Lee, D.S., El-Kashlan, H.K., Telian, S.A., Denny, D.E., Ramakrishnan, A., Nair, T.S., Disher, M.J., Sataloff, R.T., Fisher, S.G., Carey, T.E. Arch. Otolaryngol. Head Neck Surg. (2005) [Pubmed]
  29. CO2 laser surgery of the upper airway. Keane, W.M., Atkins, J.P. Surg. Clin. North Am. (1984) [Pubmed]
  30. The versatile contact Nd:YAG laser in head and neck surgery: an in vivo and clinical analysis. Brown, D.H. Laryngoscope (2000) [Pubmed]
  31. Efficacy of computed tomographic image--guided endoscopic sinus surgery in residency training programs. Casiano, R.R., Numa, W.A. Laryngoscope (2000) [Pubmed]
  32. "How I do it" - otology and neurotology. A specific issue and its solution. An alternative way of using TORP and PORP. Palva, T. Laryngoscope (1981) [Pubmed]
  33. Environmental tobacco smoke in rats. Işik, A.C., Kalender, Y., Yardimci, S., Ergün, A. The Journal of otolaryngology. (2004) [Pubmed]
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