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MeSH Review

Adenoma, Chromophobe

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Disease relevance of Adenoma, Chromophobe


High impact information on Adenoma, Chromophobe


Chemical compound and disease context of Adenoma, Chromophobe

  • At surgery, we found a large chromophobe adenoma with few PAS-positive granules and with immunostaining positive for TSH and prolactin [11].
  • Thioridazine was found to increase the serum prolactin level as well as the tumor size of a prolactin--secreting pituitary chromophobe adenoma in a schizophrenic man [12].
  • Hematoxylin and eosin-stained sections were consistent with a chromophobe adenoma [13].
  • In order to study the light microscopical alterations of pituitary tumours under dopamine agonist treatment, three groups of a total of 18 large or small cell chromophobe adenomas were analysed by light microscopical, immunohistological and morphometrical methods [14].
  • 14C-Nicotinic acid (NA) incorporation into nicotinamide adenine dinucleotide (NAD) was studied in cultures from 7 normal human pituitaries and 13 chromophobe adenomas [15].

Anatomical context of Adenoma, Chromophobe

  • A man with normal-sizes testes and a chromophobe adenoma of the pituitary was found to have elevated plasma levels of FSH and prolactin and severe deficiencies of other trophic hormones [16].

Gene context of Adenoma, Chromophobe


Analytical, diagnostic and therapeutic context of Adenoma, Chromophobe


  1. Heavy-particle therapy in acromegaly and Cushing disease. Lawrence, J.H., Tobias, C.A., Linfoot, J.A., Born, J.L., Chong, C.Y. JAMA (1976) [Pubmed]
  2. Spontaneous infarction in pituitary tumors: neurologic and therapeutic aspects. Conomy, J.P., Ferguson, J.H., Brodkey, J.S., Mitsumoto, H. Neurology (1975) [Pubmed]
  3. Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28. Panetta, R., Greenwood, M.T., Warszynska, A., Demchyshyn, L.L., Day, R., Niznik, H.B., Srikant, C.B., Patel, Y.C. Mol. Pharmacol. (1994) [Pubmed]
  4. Morphometric analysis of secretory granules and prolactin levels in chromophobe pituitary adenoma. Kornfeld, M., Buckmann, M.T., McClellan, G. Acta Neuropathol. (1981) [Pubmed]
  5. Pituitary hormone concentrations in cerebrospinal fluid in patients with prolactin and growth hormone-secreting tumors. Rolandi, E., Perria, C., Cicchetti, V., Sannia, A., Magnani, G., Rivano, C., Michelozzi, G., Barreca, T. Journal of neurosurgical sciences. (1982) [Pubmed]
  6. Pure alpha-secreting pituitary adenomas. Ridgway, E.C., Klibanski, A., Ladenson, P.W., Clemmons, D., Beitins, I.Z., McArthur, J.W., Martorana, M.A., Zervas, N.T. N. Engl. J. Med. (1981) [Pubmed]
  7. Somatostatin and regulation of prolactin secretion. Enjalbert, A., Bertrand, P., Le Dafniet, M., Epelbaum, J., Hugues, J.N., Kordon, C., Moyse, E., Peillon, F., Shu, C. Psychoneuroendocrinology (1986) [Pubmed]
  8. ACTH-producing pituitary adenoma in an infant with cysts of the kidneys and lungs. Pullins, D.I., Challa, V.R., Marshall, R.B., Davis, C.H. Histopathology (1984) [Pubmed]
  9. Pituitary-testicular function in acromegalic and hypophysectomized patients. Lindholm, J., Rasmussen, P., Korsgaard, O. Eur. J. Clin. Invest. (1977) [Pubmed]
  10. Effect of clomiphene citrate on gonadotropin responses to LRH administration in secondary amenorrhea and oligomenorrhea. Wentz, A.C., Jones, G.S., Sapp, K.C. Obstetrics and gynecology. (1976) [Pubmed]
  11. Long-standing goiter and hypothyroidism: an unusual presentation of a TSH-secreting adenoma. Langlois, M.F., Lamarche, J.B., Bellabarba, D. Thyroid (1996) [Pubmed]
  12. The effect of thioridazine on prolactinoma growth in a schizophrenic man: case report. Weingarten, J.C., Thompson, T.L. General hospital psychiatry. (1985) [Pubmed]
  13. A sparsely granulated, nonsecreting adenoma of the pars intermedia associated with galactorrhea in a male rhesus monkey (Macaca mulatta). Chalifoux, L.V., MacKey, J.J., King, N.W. Vet. Pathol. (1983) [Pubmed]
  14. Light microscopical morphometry of prolactin secreting adenomas under treatment with dopamine agonists. Hamester, U., Saeger, W., Lüdecke, D.K. Histol. Histopathol. (1987) [Pubmed]
  15. Pyridine nucleotide synthesis in normal and neoplastic human pituitary cells in culture. Gross, C.J., Harris, R.D., Seljeskog, E.L., Henderson, L.M. Cancer (1983) [Pubmed]
  16. An FSH and prolactin-secreting pituitary tumor: pituitary dynamics and testicular histology. Cunningham, G.R., Huckins, C. J. Clin. Endocrinol. Metab. (1977) [Pubmed]
  17. Human pituitary tumours in organ culture with correlation to clinical data. Anniko, M., Wersäll, J. Acta Otolaryngol. (1980) [Pubmed]
  18. Twenty-four-hour prolactin secretory patterns in women with galactorrhea, normal menses, normal random prolacting levels and abnormal sellar tomograms. Kapcala, L.P., Molitch, M.E., Arno, J., King, L.W., Reichlin, S., Wolpert, S.M. J. Endocrinol. Invest. (1984) [Pubmed]
  19. Localization of prolactin in chromophobe pituitary adenomas: study of human necropsy material by immunoperoxidase technique. Kovacs, K., Corenblum, B., Sirek, A.M., Penz, G., Ezrin, C. J. Clin. Pathol. (1976) [Pubmed]
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