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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Capnography

  • Monitoring with capnography allowed for rapid titration of propofol at the earliest signs of respiratory depression [1].
  • Breathing stability was estimated by at least 6 h of capnography and from these records apnea index (AI, episodes/hour) and cyclic changes of end-tidal CO2 (c-PETCO2, cycles/hour) were derived [2].
  • Pneumotachography, capnography and airway occlusion pressures at 0.1 s (P degree 0.1) were used before and during both mild hypoxia (end-tidal O2 tension 8.7 kPa) and hypercapnia achieved by an inspired CO2 concentration of 5% [3].

Psychiatry related information on Capnography

  • By combining capnography, during the Effort Test, with analysis of blood gases and specific electrolytes, the effort-syndrome hypothesis was further tested in the present study [4].

High impact information on Capnography


Biological context of Capnography

  • Pulse rate, blood pressure, blood gases (PaO2 and PaCO2) and pH, blood lactic acid concentration, and capnography were used to evaluate the physiologic responses of sea turtles to isoflurane [9].
  • The sedative effect was evaluated and measurements by pneumotachography and in-line capnography were made immediately after induction of sleep, just before the start of surgery, during surgery and after surgery both before and after 3 min of about 2% CO2 inhalation [10].

Anatomical context of Capnography


Associations of Capnography with chemical compounds

  • Capnography, the science of CO2 waveforms analysis, can play a role in the management of mechanically ventilated patients [12].
  • This article discusses the clinical applications and limitations of capnography and end-tidal CO2 monitoring [13].
  • Capnography and measurement of the respiratory minute volume were carried out on normal, conscious subjects during breathing of pure O2 via a Mapleson C modification of a Magill attachment, with and without continuous gas evacuation [14].
  • METHODS: The authors performed continuous capnography on a convenience sample of 20 ED pediatric patients who received ketamine 1.5 mg/kg IV for procedural sedation [15].
  • OBJECTIVES: 1) To evaluate the relationship between measured serum bicarbonate (HCO(3)) and ETCO(2) measured via nasal capnography in children with suspected DKA; and 2) to assess the ability of capnography to predict DKA [16].

Gene context of Capnography

  • Pulmonary function measurements in dolphins using capnography [17].
  • Misleading capnography in primary pulmonary hypertension [18].
  • BACKGROUND: The Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland recommend the use of capnography to ensure correct tracheal tube placement in the theater environment [19].
  • Increases in CBFV and CBF seen in previous studies may be related to an increasing PaCO2 when maintenance of normocarbia is based on only real-time capnography with a constant PetCo2 rather than additional arterial blood gas monitoring [20].

Analytical, diagnostic and therapeutic context of Capnography

  • This report, of a 16-month-old child recovering from surgery for a posterior fossa tumour, illustrates how pneumotachography, capnography and occlusion testing before and during CO2 challenge can be of clinical value in the analysis of a difficult respiratory disturbance in the early postoperative period [21].
  • Several CO2 detection devices are suitable for emergency transport, including colorimetry, capnometry, and capnography [22].


  1. Gastroenterologist-administered propofol versus meperidine and midazolam for advanced upper endoscopy: a prospective, randomized trial. Vargo, J.J., Zuccaro, G., Dumot, J.A., Shermock, K.M., Morrow, J.B., Conwell, D.L., Trolli, P.A., Maurer, W.G. Gastroenterology (2002) [Pubmed]
  2. Ventilatory post-stimulus potentiation in patients with brain damage. Georgopoulos, D., Mitrouska, I., Koletsos, K., Markopoulou, K., Riggos, D., Patakas, D., Anthonisen, N.R. Am. J. Respir. Crit. Care Med. (1995) [Pubmed]
  3. Poikilocapnic hypoxic ventilatory response in humans during 0.85 MAC isoflurane anesthesia. Sjögren, D., Sollevi, A., Ebberyd, A., Lindahl, S.G. Acta anaesthesiologica Scandinavica. (1994) [Pubmed]
  4. The measurement of respiratory and metabolic parameters of patients and controls before and after incremental exercise on bicycle: supporting the effort syndrome hypothesis? von Schéele, B.H., von Schéele, I.A. Applied psychophysiology and biofeedback. (1999) [Pubmed]
  5. Effects of age and exercise on physiological dead space during simulated dives at 2.8 ATA. Mummery, H.J., Stolp, B.W., deL Dear, G., Doar, P.O., Natoli, M.J., Boso, A.E., Archibald, J.D., Hobbs, G.W., El-Moalem, H.E., Moon, R.E. J. Appl. Physiol. (2003) [Pubmed]
  6. A response to 'Another use for capnography', White SM, Anaesthesia 2003; 58: 189-90. Shankar, R. Anaesthesia. (2003) [Pubmed]
  7. Capnography and severe COPD. Broka, S.M., Boujlel, S. Anesth. Analg. (2002) [Pubmed]
  8. Capnography via the LTA: friend or foe? Metz, S. Anesth. Analg. (1999) [Pubmed]
  9. Anesthetic and postanesthetic management of sea turtles. Moon, P.F., Stabenau, E.K. J. Am. Vet. Med. Assoc. (1996) [Pubmed]
  10. Ventilation and ventilatory CO2 response in children during halothane anaesthesia after non-opioid (midazolam) and opioid (papaveretum) premedication. Charlton, A.J., Lindahl, S.G., Hatch, D.J. Acta anaesthesiologica Scandinavica. (1986) [Pubmed]
  11. Metabolic changes after tourniquet release. Deen, L., Nyst, C.L., Zuurmond, W.W. Acta anaesthesiologica Belgica. (1982) [Pubmed]
  12. Capnography in mechanically ventilated patients. Carlon, G.C., Ray, C., Miodownik, S., Kopec, I., Groeger, J.S. Crit. Care Med. (1988) [Pubmed]
  13. Capnography for adults. Stock, M.C. Critical care clinics. (1995) [Pubmed]
  14. The flow requirement in a non-polluting Mapleson C circuit. Christensen, K.N. Acta anaesthesiologica Scandinavica. (1976) [Pubmed]
  15. Ventilatory response during dissociative sedation in children-a pilot study. Kim, G., Green, S.M., Denmark, T.K., Krauss, B. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. (2003) [Pubmed]
  16. End-tidal carbon dioxide predicts the presence and severity of acidosis in children with diabetes. Fearon, D.M., Steele, D.W. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. (2002) [Pubmed]
  17. Pulmonary function measurements in dolphins using capnography. Van Elk, C.E., Epping, N., Gans, S.J. Vet. Rec. (2001) [Pubmed]
  18. Misleading capnography in primary pulmonary hypertension. Yogasakaran, B.S. J. Cardiothorac. Vasc. Anesth. (1992) [Pubmed]
  19. A survey of the use of capnography for the confirmation of correct placement of tracheal tubes in pediatric intensive care units in the UK. Cumming, C., McFadzean, J. Paediatric anaesthesia. (2005) [Pubmed]
  20. The effects of fentanyl and sufentanil on cerebral hemodynamics. Hänel, F., Werner, C., von Knobelsdorff, G., Schulte am Esch, J. Journal of neurosurgical anesthesiology. (1997) [Pubmed]
  21. Respiratory disturbance and posterior fossa surgery. A case report. Yates, A.P., Sumner, E., Lindahl, S.G. Anaesthesia. (1986) [Pubmed]
  22. Capnography: beyond the numbers. Rhoades, C., Thomas, F. Air Med. J. (2002) [Pubmed]
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