Disease relevance of Guadeloupe

• HTLV-I associated sicca syndrome in Guadeloupe: lack of relation with a peculiar encoding sequence of surface envelope glycoprotein [1].
• 854 sera collected from blood donors in Guadeloupe were screened for Helicobacter pylori immunoglobulin G antibodies by a commercial enzyme-linked immunosorbent assay kit [2].
• Evaluation of neonatal sepsis screening in a tropical area. Part I: Major risk factors for bacterial carriage at birth in Guadeloupe [3].

High impact information on Guadeloupe

• The obtained dendrogram indicated small genetic distances between France, Guadeloupe and Réunion as well as between France and Finland. Senegal showed a distant genetic relationship with the other countries and, interestingly, an inverted ratio of coding/non-coding (KIR2DS4/1D) alleles compared with Caucasians [4].
• To this end, we used polymerase chain reaction-sequence-specific primers to evaluate KIR gene in five selected populations (France, Guadeloupe, Senegal, Finland and Réunion) [4].
• Prostate cancer incidence in guadeloupe, a French Caribbean archipelago [5].
• Allelic frequency variation at the malate dehydrogenase (E.C.1.1.1.37) polymorphic locus (Mdh-1) was analysed during several successive generations in four strains of Schistosoma mansoni from Guadeloupe, maintained experimentally on mice [6].
• Analyses of LDH, MDH, AcP, PGM, GPI, G6PDH and HK by isoelectric focusing provided no evidence for the involvement of S. rodhaini in the recent evolution of the schistosomes currently endemic in Guadeloupe [7].

Biological context of Guadeloupe

• These findings suggest that FABP2 does not represent a major gene for Type 2 DM in this migrant Indian population living in Guadeloupe, but seems to be related to the metabolic insulin resistance syndrome [8].
• beta S haplotypes, alpha-globin gene status, and hematological data of sickle cell disease patients in Guadeloupe (F.W.I.) [9].

Associations of Guadeloupe with chemical compounds

• Faecal water content and egg survival of goat gastro-intestinal strongyles under dry tropical conditions in Guadeloupe [10].
• Mifepristone-misoprostol medical abortion: home administration of misoprostol in Guadeloupe [11].
• Subjects were classified as 'diabetic' when they were either already known or when their fasting plasma glucose was above 8.0 mmol/l. The total age and sex standardized prevalence of diabetes among the adult population of Guadeloupe can be estimated at 6.6% [12].
• Nymphs from Guadeloupe were 9.5 times more susceptible to chlorpyrifos than nymphs from Puerto Rico [13].
• The susceptibility of larvae from Guadeloupe to acaricides tested ranged from LC50 0.000012% for deltamethrin to 0.0141% for ethion [13].

Gene context of Guadeloupe

• We determined the frequencies of UGT1A1 promoter alleles in 171 SCA children and 153 SCA adults regularly followed for a number of years at the Guadeloupe sickle cell center [14].
• We report a case of P. falciparum infection observed in Paris and presumably acquired in Guadeloupe, a French Caribbean island where malaria has been considered to be eradicated since 1970 [15].
• The 15th Annual Meeting of the Winter Conference on Neural Plasticity, Guadeloupe, French Antilles, February 23-28, 2003 [16].
• Primary and secondary dapsone resistance were studied among lepromatous patients living in Martinique, Guadeloupe, New Caledonia, Tahiti, Senegal, and Paris. Four hundred fifteen biopsies were taken from clinically active and bacteriologically positive (bacterial index greater than 2) patients in the 6-year period of 1980-1985 [17].

References