Gene Review:
NEDD9 - neural precursor cell expressed,...
Homo sapiens
Synonyms:
CAS-L, CAS2, CASL, CASS2, CRK-associated substrate-related protein, ...
- Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid. Merrill, R.A., See, A.W., Wertheim, M.L., Clagett-Dame, M. Dev. Dyn. (2004)
- Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Kim, M., Gans, J.D., Nogueira, C., Wang, A., Paik, J.H., Feng, B., Brennan, C., Hahn, W.C., Cordon-Cardo, C., Wagner, S.N., Flotte, T.J., Duncan, L.M., Granter, S.R., Chin, L. Cell (2006)
- HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Natarajan, M., Stewart, J.E., Golemis, E.A., Pugacheva, E.N., Alexandropoulos, K., Cox, B.D., Wang, W., Grammer, J.R., Gladson, C.L. Oncogene (2006)
- Cellular targets for transformation by the adenovirus E1A proteins. Whyte, P., Williamson, N.M., Harlow, E. Cell (1989)
- Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. Berry, R.J., Li, Z., Erickson, J.D., Li, S., Moore, C.A., Wang, H., Mulinare, J., Zhao, P., Wong, L.Y., Gindler, J., Hong, S.X., Correa, A. N. Engl. J. Med. (1999)
- A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. O'Neill, G.M., Seo, S., Serebriiskii, I.G., Lessin, S.R., Golemis, E.A. Cancer Res. (2007)
- The absence of a relation between the periconceptional use of vitamins and neural-tube defects. National Institute of Child Health and Human Development Neural Tube Defects Study Group. Mills, J.L., Rhoads, G.G., Simpson, J.L., Cunningham, G.C., Conley, M.R., Lassman, M.R., Walden, M.E., Depp, O.R., Hoffman, H.J. N. Engl. J. Med. (1989)
- Three-dimensional computergraphic analysis of apraxia. Neural representations of learned movement. Poizner, H., Mack, L., Verfaellie, M., Rothi, L.J., Heilman, K.M. Brain (1990)
- Electrophysiological correlates of similarity-based interference during detection of visual forms. Conci, M., Gramann, K., Müller, H.J., Elliott, M.A. Journal of cognitive neuroscience. (2006)
- Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. Rogers, R.D., Ramnani, N., Mackay, C., Wilson, J.L., Jezzard, P., Carter, C.S., Smith, S.M. Biol. Psychiatry (2004)
- Immunoreactivity of the nuclear antigen p105 is associated with plaques and tangles in Alzheimer's disease. Masliah, E., Mallory, M., Alford, M., Hansen, L.A., Saitoh, T. Lab. Invest. (1993)
- The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Dyson, N., Buchkovich, K., Whyte, P., Harlow, E. Cell (1989)
- The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Buchkovich, K., Duffy, L.A., Harlow, E. Cell (1989)
- Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. Schmid, R.M., Perkins, N.D., Duckett, C.S., Andrews, P.C., Nabel, G.J. Nature (1991)
- Letter: Neural crest, limb development, and thalidomide embryopathy. Gardner, E., O'Rahilly, R. Lancet (1976)
- Detection by monoclonal antibodies of an early membrane protein induced by Epstein-Barr virus. Balachandran, N., Pittari, J., Hutt-Fletcher, L.M. J. Virol. (1986)
- A neural network classifier for cerebral perfusion imaging. Chan, K.H., Johnson, K.A., Becker, J.A., Satlin, A., Mendelson, J., Garada, B., Holman, B.L. J. Nucl. Med. (1994)
- 17 beta-estradiol inhibits tumor necrosis factor-alpha-induced nuclear factor-kappa B activation by increasing nuclear factor-kappa B p105 level in MCF-7 breast cancer cells. Hsu, S.M., Chen, Y.C., Jiang, M.C. Biochem. Biophys. Res. Commun. (2000)
- Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion. Zheng, M., McKeown-Longo, P.J. J. Biol. Chem. (2002)
- Atrophin-1-interacting protein 4/human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways. Feng, L., Guedes, S., Wang, T. J. Biol. Chem. (2004)
- Of mice and men: cancer gene discovery using comparative oncogenomics. Tomlins, S.A., Chinnaiyan, A.M. Cancer Cell (2006)
- T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G. Ohashi, Y., Tachibana, K., Kamiguchi, K., Fujita, H., Morimoto, C. J. Biol. Chem. (1998)
- Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Law, S.F., Estojak, J., Wang, B., Mysliwiec, T., Kruh, G., Golemis, E.A. Mol. Cell. Biol. (1996)
- Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells. Manié, S.N., Beck, A.R., Astier, A., Law, S.F., Canty, T., Hirai, H., Druker, B.J., Avraham, H., Haghayeghi, N., Sattler, M., Salgia, R., Griffin, J.D., Golemis, E.A., Freedman, A.S. J. Biol. Chem. (1997)
- The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Law, S.F., O'Neill, G.M., Fashena, S.J., Einarson, M.B., Golemis, E.A. Mol. Cell. Biol. (2000)
- Cytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinase. Zhang, Z., Hernandez-Lagunas, L., Horne, W.C., Baron, R. J. Biol. Chem. (1999)
- MICAL, a novel CasL interacting molecule, associates with vimentin. Suzuki, T., Nakamoto, T., Ogawa, S., Seo, S., Matsumura, T., Tachibana, K., Morimoto, C., Hirai, H. J. Biol. Chem. (2002)
- A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. Liu, X., Elia, A.E., Law, S.F., Golemis, E.A., Farley, J., Wang, T. EMBO J. (2000)
- Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers. Yi, J., Kloeker, S., Jensen, C.C., Bockholt, S., Honda, H., Hirai, H., Beckerle, M.C. J. Biol. Chem. (2002)
- G protein-coupled receptors in gastrointestinal physiology. IV. Neural regulation of gastrointestinal smooth muscle. Sanders, K.M. Am. J. Physiol. (1998)
- Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1. Nourry, C., Maksumova, L., Pang, M., Liu, X., Wang, T. BMC Cell Biol. (2004)
- Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway. van Seventer, G.A., Salmen, H.J., Law, S.F., O'Neill, G.M., Mullen, M.M., Franz, A.M., Kanner, S.B., Golemis, E.A., van Seventer, J.M. Eur. J. Immunol. (2001)
- Structural requirements for beta1 integrin-mediated tyrosine phosphorylation in human T cells. Finkelstein, L.D., Reynolds, P.J., Hunt, S.W., Shimizu, Y. J. Immunol. (1997)
- The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions. Bargon, S.D., Gunning, P.W., O'Neill, G.M. Biochim. Biophys. Acta (2005)
- Ligation of the T cell antigen receptor induces tyrosine phosphorylation of p105CasL, a member of the p130Cas-related docking protein family, and its subsequent binding to the Src homology 2 domain of c-Crk. Kanda, H., Mimura, T., Morino, N., Hamasaki, K., Nakamoto, T., Hirai, H., Morimoto, C., Yazaki, Y., Nojima, Y. Eur. J. Immunol. (1997)
- Identification of an atypical lipoprotein-binding protein from human aortic smooth muscle as T-cadherin. Tkachuk, V.A., Bochkov, V.N., Philippova, M.P., Stambolsky, D.V., Kuzmenko, E.S., Sidorova, M.V., Molokoedov, A.S., Spirov, V.G., Resink, T.J. FEBS Lett. (1998)
- Oxidative stress oppositely modulates protein tyrosine phosphorylation stimulated by muscarinic G protein-coupled and epidermal growth factor receptors. Jope, R.S., Song, L., Grimes, C.A., Zhang, L. J. Neurosci. Res. (1999)
- The hematopoietic isoform of cas-hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking. Regelmann, A.G., Danzl, N.M., Wanjalla, C., Alexandropoulos, K. Immunity (2006)