Disease relevance of Brachial Plexus Neuropathies

• We present a case of a 69-year-old woman who developed brachial plexopathy and long thoracic nerve palsy secondary to compression from a hematoma while receiving heparin therapy for the treatment of a stroke [1].
• Standard axial CT supplemented by two-dimensional reconstruction in coronal, sagittal, and oblique planes was used to evaluate 35 patients with a history of breast cancer and clinical symptoms suggestive of brachial plexopathy [2].
• Nerve conduction studies and concentric needle electrode examination of the upper extremities performed respectively 3 and 10 months after the onset of symptoms confirmed a severe anterior interosseous neuropathy and excluded more common conditions such as carpal tunnel syndrome, cervical radiculopathy or brachial plexopathy [3].
• Serum creatine kinase was greater than 19,000 units/l. A diagnosis of focal rhabdomyolysis and left brachial plexopathy was made [4].
• We report a third case of brachial plexopathy, presumably related to vasculitis, in a patient with systemic sclerosis, which improved after cyclophosphamide therapy [5].

High impact information on Brachial Plexus Neuropathies

• Brachial plexopathy after intraarterial cisplatin [6].
• We reviewed clinical and electrodiagnostic features of 16 patients with neoplastic brachial plexopathy (NBP) and 17 patients with radiation-induced plexopathy (RBP) [7].
• Unilateral nail changes secondary to adriamycin: the protective effect of brachial plexopathy [8].
• It has been found that in cases of obstetric brachial plexopathy, injured phrenic nerve or C3/4/5 roots may sprout into the adjacent injured upper and middle trunks of the brachial plexus [9].
• Brachial plexopathy after botulinum toxin administration for cervical dystonia [10].

Chemical compound and disease context of Brachial Plexus Neuropathies

• H-reflexes of the flexor carpi radialis muscle were studied in 52 controls and 25 cancer patients with radiation-induced brachial plexopathy [11].
• Upper trunk brachial plexopathy. The stinger syndrome [12].
• Despite treatment with high doses of methylprednisolone, intravenous immunoglobulins and repeated cerebrospinal fluid drainage, both brachial plexopathy and the PTCS continued to worsen [13].
• The types of palsy were four Erb's palsy (C5, C6) and two C5-C7 palsy [14].
• RESULTS: For the ruptured upper and/or middle trunk injury (Erb's palsy), better shoulder and elbow function was observed in those who received numerous short grafts from C5 to the suprascapular and posterior division and from the C6 spinal nerve to the anterior division of the upper trunk [15].

Anatomical context of Brachial Plexus Neuropathies

• The article describes the MR anatomy of the brachial plexus in the axial, coronal, and sagittal planes and reviews the MR characteristics of traumatic and nontraumatic etiologies of brachial plexopathy [16].

Gene context of Brachial Plexus Neuropathies

• OBJECTIVE: We sought to evaluate from a behavioral and histological viewpoint the effect of local administration of glial cell line-derived neurotrophic factor (GDNF) on neonatal preganglionic Erb's palsy in rats [17].
• HNPP patients more often showed recurrent episodes, brachial plexopathy, and clinical or electrophysiologic involvement of other nerves [18].
• Finally, even though the shoulder muscles regain their strenght, the "Erb engram" may remain as a mark of Erb's palsy [19].
• Perinatal brachial plexus palsy (PBPP) has been traditionally classified into three types: upper plexus palsy (Erb's) affecting the C5, C6, and +/- C7 nerve roots, lower plexus palsy (Klumpke's) affecting the C8 and T1 nerve roots, and total plexus palsy [20].

Analytical, diagnostic and therapeutic context of Brachial Plexus Neuropathies

• This study was designed to determine the cause of upper trunk brachial plexopathy, which is referred to as a "stinger" or a "burner." This injury often has been thought to occur secondary to traction when an athlete sustains a lateral flexion injury of the neck [12].

References