Disease relevance of Epidural Abscess

• Pyoderma gangrenosum and spinal epidural abscess after subcutaneous administration of recombinant human erythropoietin [1].
• A 50% complication rate included osteomyelitis, cerebrospinal fluid rhinorrhea, meningitis, brain abscess, epidural abscess, and syndrome of inappropriate antidiuretic hormone [2].
• Oral fluconazole appears to be useful in the management of candida spondylodiscitis complicated by epidural abscess formation [3].
• Two cases of epidural abscess, one case of bacterial meningitis, and one case of aseptic meningitis have been reported following epidural steroid injections [4].
• Although the epidural abscess was initially treated with antibiotic (cefozopran) for 5 days, he subsequently developed motor weakness, paresthesia and urinary retention [5].

High impact information on Epidural Abscess

• Gadolinium-enhanced magnetic resonance imaging was the most useful diagnostic test, and we recommend that it be performed promptly in any patient with clinical features suggesting spinal epidural abscess since early surgical drainage and appropriate antibiotics may yield a favorable outcome [6].
• Despite treatment with imipenem, the patient developed a spinal epidural abscess, from which imipenem-resistant S. algae was isolated [7].
• We report the association of extensive spinal epidural abscess and Currarino triad in a young child [8].
• Spinal epidural abscess successfully treated with percutaneous, computed tomography-guided, needle aspiration and parenteral antibiotic therapy: case report and review of the literature [9].
• She received surgical drainage of the spinal epidural abscess and i.v. amphotericin B 1 mg/kg/day for eight weeks [10].

Chemical compound and disease context of Epidural Abscess

• Epidural abscess following epidural steroid and local anaesthetic injection [11].
• Exacerbation of chronic epidural abscess following a fludarabine-based preparative regimen [12].
• We reviewed serial MRI with and without gadolinium-DTPA in eight patients with spinal epidural abscess and correlated the findings and the clinical manifestations [13].
• STUDY DESIGN: This is a report of three cases of epidural abscess occurring after use of intraoperative epidural methylprednisolone in 31 patients who had undergone lumbar microdiscectomy [14].
• RESULTS: Additional investigation demonstrated an osteolytic process in the body of C3 with a large epidural abscess compressing the spinal cord [15].

Gene context of Epidural Abscess

• We report a patient with rheumatoid arthritis, receiving steroid therapy, in whom an extradural abscess did not present until 23 days after the insertion of a thoracic extradural catheter to provide postoperative analgesia [16].
• The patient continued to spike fevers, and a repeat lumbar MRI 1 week later clearly demonstrated the presence of an epidural abscess at the level of the PLIF surgery [17].
• Imaging showed D9--11 vertebral involvement and destruction of the D10 vertebral body with angulation and a large dorsally placed, multiloculated epidural abscess extending from D6 to L2 [18].
• CONCLUSIONS: New spinal pain, radicular symptoms or signs, and a raised ESR were the most consistent early abnormalities in patients with a spinal epidural abscess [19].

Analytical, diagnostic and therapeutic context of Epidural Abscess

• The epidural abscess resolved clinically and radiologically after treatment for N. gonorrhoeae with ceftriaxone [20].

References