Disease relevance of Meningitis, Aseptic

• The CSF was more likely positive for an enterovirus if it was drawn from a young patient with aseptic meningitis during the summer of fall months [1].
• Trimethoprim-induced aseptic meningitis and uveitis [2].
• We present a patient with 3 episodes of aseptic meningitis due to trimethoprim-sulfamethoxazole, and then review the topic of drug-induced meningitis [3].
• Pentoxifylline-induced aseptic meningitis in a patient with mixed connective tissue disease [4].
• CSF pleocytosis was observed in asymptomatic neurologically normal subjects, in patients with aseptic meningitis, and those with inflammatory demyelinating neuropathies, but infrequently in subjects with AIDS dementia complex [5].

High impact information on Meningitis, Aseptic

• Aseptic meningitis as an adverse effect of co-trimoxazole [6].
• CONTEXT: Enterovirus (EV) infection, the most common cause of aseptic meningitis, can be rapidly diagnosed with an EV-specific reverse transcriptase polymerase chain reaction (EV-PCR) test [7].
• Trimethoprim-induced aseptic meningitis [8].
• The clinical relevance of 'CSF viral culture'. A two-year experience with aseptic meningitis in Rochester, NY [1].
• Tolmetin-induced aseptic meningitis [9].

Chemical compound and disease context of Meningitis, Aseptic

• Aseptic meningitis from over-the-counter ibuprofen [10].
• Complement C3 and factor B cerebrospinal fluid concentrations in bacterial and aseptic meningitis [11].
• Recurrent aseptic meningitis due to sulindac [12].
• Phenazopyridine and aseptic meningitis [13].
• Cephalosporin-induced recurrent aseptic meningitis [14].

Anatomical context of Meningitis, Aseptic

• The influence of CSF on the active and total E-rosette test with peripheral blood (PB) lymphocytes of 12 children with aseptic meningitis (AM) was estimated [15].
• This phenomenon might in part explain the higher proportion of T cells appearing in the CSF during aseptic meningitis [15].
• The identification of a specific viral agent in body fluids, especially the CSF, in a patient with aseptic meningitis is of more than academic interest, since it can shorten duration of hospital stay and eliminate unnecessary antimicrobial therapy [16].
• Synthesis of the complement factors C3 and C4 within the central nervous system over the course of aseptic meningitis [17].
• The determinations of CSF/plasma C9 ratio and C9 index, equal to (CSF C9/plasma C9): (CSF albumin/plasma albumin), thus accounting for changes of plasma C9 levels as well as damaged blood brain barrier, documented the existence of local consumption of C9 in aseptic meningitis [18].

Gene context of Meningitis, Aseptic

• When the patients with aseptic meningitis had meningeal symptoms, IL-10 in the CSF was detectable in 14 of 22 patients (88 +/- 146 ng/L, n = 31) [19].
• CXCL5 was not detectable in patients with aseptic meningitis or control subjects [20].
• The augmented production of IL-8 in CSF may account for the inflammation in bacterial meningitis being more severe than that in aseptic meningitis [21].
• These results suggest that IFN-gamma produced in the inflamed intrathecal space may be associated with the pathogenesis of aseptic meningitis, especially the production of fever [22].
• CSF IL-6, IL-8 and TNF-alpha levels in patients with aseptic meningitis were also significantly higher than those in the control group [23].

Analytical, diagnostic and therapeutic context of Meningitis, Aseptic

• We investigated whether sTNF-R increases in CSF during patients' acute stage of bacterial and aseptic meningitis by measuring p60 sTNF-R in CSF by a sandwich enzyme immunoassay [24].
• Unusual effects of metrizamide lumbar myelography. Constellation of aseptic meningitis, arachnoiditis, communicating hydrocephalus, and Guillaine-Barré syndrome [25].
• Oligoclonal immunoglobulins (Ig) demonstrble as bands by agarose-gel electrophoresis of CSF were characterized in ten patients with aseptic meningitis [26].
• Rarely, haematological (Coombs' test positive haemolysis), neurological (aseptic meningitis) or renal (transient rises in serum creatinine) adverse effects may be seen when high doses of IVIG are used for immunomodulatory purposes [27].
• We report a case of aseptic meningitis related to TMP-SMX ingestion that caused severe derangements of the patient's vital signs, requiring Intensive Care Unit admittance [28].

References