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Chemical Compound Review

nitrosonium     azanylidyneoxidanium

Synonyms: nitrilooxonium, Nitrosyl ion, CHEBI:29120, HMDB03378, NO(+), ...
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Disease relevance of nitric oxide


Psychiatry related information on nitric oxide


High impact information on nitric oxide


Chemical compound and disease context of nitric oxide


Biological context of nitric oxide


Anatomical context of nitric oxide


Associations of nitric oxide with other chemical compounds


Gene context of nitric oxide


Analytical, diagnostic and therapeutic context of nitric oxide


  1. Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. Clinical Inhaled Nitric Oxide Research Group. Clark, R.H., Kueser, T.J., Walker, M.W., Southgate, W.M., Huckaby, J.L., Perez, J.A., Roy, B.J., Keszler, M., Kinsella, J.P. N. Engl. J. Med. (2000) [Pubmed]
  2. Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis. Martin, P.Y., Ginès, P., Schrier, R.W. N. Engl. J. Med. (1998) [Pubmed]
  3. Nitric oxide and vascular disease. Loscalzo, J. N. Engl. J. Med. (1995) [Pubmed]
  4. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Mannick, J.B., Asano, K., Izumi, K., Kieff, E., Stamler, J.S. Cell (1994) [Pubmed]
  5. Nitric oxide synthesis in infantile hypertrophic pyloric stenosis. Michel, T. N. Engl. J. Med. (1992) [Pubmed]
  6. Nitric oxide and AIDS dementia. Fuchs, D., Baier-Bitterlich, G., Wachter, H. N. Engl. J. Med. (1995) [Pubmed]
  7. Nitric oxide and substance dependence. Tayfun Uzbay, I., Oglesby, M.W. Neuroscience and biobehavioral reviews. (2001) [Pubmed]
  8. Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Sultana, R., Poon, H.F., Cai, J., Pierce, W.M., Merchant, M., Klein, J.B., Markesbery, W.R., Butterfield, D.A. Neurobiol. Dis. (2006) [Pubmed]
  9. Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease? Sullivan, M.E., Thompson, C.S., Dashwood, M.R., Khan, M.A., Jeremy, J.Y., Morgan, R.J., Mikhailidis, D.P. Cardiovasc. Res. (1999) [Pubmed]
  10. Nitric oxide synthase inhibition reduces wakefulness. Dzoljic, M.R., De Vries, R. Neuropharmacology (1994) [Pubmed]
  11. Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. Matsushita, K., Morrell, C.N., Cambien, B., Yang, S.X., Yamakuchi, M., Bao, C., Hara, M.R., Quick, R.A., Cao, W., O'Rourke, B., Lowenstein, J.M., Pevsner, J., Wagner, D.D., Lowenstein, C.J. Cell (2003) [Pubmed]
  12. S-nitrosylation of NSF controls membrane trafficking. Söllner, T.H., Sequeira, S. Cell (2003) [Pubmed]
  13. Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding. Lanas, A., Bajador, E., Serrano, P., Fuentes, J., Carreño, S., Guardia, J., Sanz, M., Montoro, M., Sáinz, R. N. Engl. J. Med. (2000) [Pubmed]
  14. Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Son, H., Hawkins, R.D., Martin, K., Kiebler, M., Huang, P.L., Fishman, M.C., Kandel, E.R. Cell (1996) [Pubmed]
  15. Nitric oxide regulates cell proliferation during Drosophila development. Kuzin, B., Roberts, I., Peunova, N., Enikolopov, G. Cell (1996) [Pubmed]
  16. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Eliasson, M.J., Sampei, K., Mandir, A.S., Hurn, P.D., Traystman, R.J., Bao, J., Pieper, A., Wang, Z.Q., Dawson, T.M., Snyder, S.H., Dawson, V.L. Nat. Med. (1997) [Pubmed]
  17. Coordinated Regulation of the Neisseria gonorrhoeae-truncated Denitrification Pathway by the Nitric Oxide-sensitive Repressor, NsrR, and Nitrite-insensitive NarQ-NarP. Overton, T.W., Whitehead, R., Li, Y., Snyder, L.A., Saunders, N.J., Smith, H., Cole, J.A. J. Biol. Chem. (2006) [Pubmed]
  18. Nitric oxide modulates glutathione synthesis during endotoxemia. Payabvash, S., Ghahremani, M.H., Goliaei, A., Mandegary, A., Shafaroodi, H., Amanlou, M., Dehpour, A.R. Free Radic. Biol. Med. (2006) [Pubmed]
  19. Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes. Farías, M., San Martín, R., Puebla, C., Pearson, J.D., Casado, J.F., Pastor-Anglada, M., Casanello, P., Sobrevia, L. J. Cell. Physiol. (2006) [Pubmed]
  20. Effect of 1-week losartan administration on bile duct-ligated cirrhotic rats with portal hypertension. Yang, Y.Y., Lin, H.C., Huang, Y.T., Lee, T.Y., Hou, M.C., Lee, F.Y., Liu, R.S., Chang, F.Y., Lee, S.D. J. Hepatol. (2002) [Pubmed]
  21. Nitric oxide acts directly in the presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons. Arancio, O., Kiebler, M., Lee, C.J., Lev-Ram, V., Tsien, R.Y., Kandel, E.R., Hawkins, R.D. Cell (1996) [Pubmed]
  22. Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells. Peunova, N., Enikolopov, G. Nature (1993) [Pubmed]
  23. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., Zeiher, A.M. Nature (1999) [Pubmed]
  24. Neurobiology. Nitric oxide and bad behaviour. Coles, H. Nature (1995) [Pubmed]
  25. Nitric oxide in mucosal immunity. Green, S.J. Nat. Med. (1995) [Pubmed]
  26. Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Brenman, J.E., Chao, D.S., Xia, H., Aldape, K., Bredt, D.S. Cell (1995) [Pubmed]
  27. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. Rajfer, J., Aronson, W.J., Bush, P.A., Dorey, F.J., Ignarro, L.J. N. Engl. J. Med. (1992) [Pubmed]
  28. Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. Vanderwinden, J.M., Mailleux, P., Schiffmann, S.N., Vanderhaeghen, J.J., De Laet, M.H. N. Engl. J. Med. (1992) [Pubmed]
  29. Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus. Zhuo, M., Small, S.A., Kandel, E.R., Hawkins, R.D. Science (1993) [Pubmed]
  30. Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors. Dubey, R.K., Jackson, E.K., Lüscher, T.F. J. Clin. Invest. (1995) [Pubmed]
  31. Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells. Filippov, G., Bloch, D.B., Bloch, K.D. J. Clin. Invest. (1997) [Pubmed]
  32. Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras. Yun, H.Y., Gonzalez-Zulueta, M., Dawson, V.L., Dawson, T.M. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  33. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Dawson, T.M., Bredt, D.S., Fotuhi, M., Hwang, P.M., Snyder, S.H. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  34. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. Papapetropoulos, A., García-Cardeña, G., Madri, J.A., Sessa, W.C. J. Clin. Invest. (1997) [Pubmed]
  35. Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS. Hewett, S.J., Csernansky, C.A., Choi, D.W. Neuron (1994) [Pubmed]
  36. Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. Tetsuka, T., Daphna-Iken, D., Miller, B.W., Guan, Z., Baier, L.D., Morrison, A.R. J. Clin. Invest. (1996) [Pubmed]
  37. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Hofseth, L.J., Saito, S., Hussain, S.P., Espey, M.G., Miranda, K.M., Araki, Y., Jhappan, C., Higashimoto, Y., He, P., Linke, S.P., Quezado, M.M., Zurer, I., Rotter, V., Wink, D.A., Appella, E., Harris, C.C. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  38. Nitric oxide activates cyclooxygenase enzymes. Salvemini, D., Misko, T.P., Masferrer, J.L., Seibert, K., Currie, M.G., Needleman, P. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  39. Vascular endothelial cells synthesize nitric oxide from L-arginine. Palmer, R.M., Ashton, D.S., Moncada, S. Nature (1988) [Pubmed]
  40. Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients. St Clair, E.W., Wilkinson, W.E., Lang, T., Sanders, L., Misukonis, M.A., Gilkeson, G.S., Pisetsky, D.S., Granger, D.I., Weinberg, J.B. J. Exp. Med. (1996) [Pubmed]
  41. Cardiac preservation is enhanced in a heterotopic rat transplant model by supplementing the nitric oxide pathway. Pinsky, D.J., Oz, M.C., Koga, S., Taha, Z., Broekman, M.J., Marcus, A.J., Liao, H., Naka, Y., Brett, J., Cannon, P.J. J. Clin. Invest. (1994) [Pubmed]
  42. Nitric oxide and impaired oxygenation before and after liver transplantation. Teramoto, S., Matsuse, T., Ouchi, Y. Ann. Intern. Med. (1999) [Pubmed]
  43. Increased nitric oxide production in patients with hypotension during hemodialysis. Yokokawa, K., Mankus, R., Saklayen, M.G., Kohno, M., Yasunari, K., Minami, M., Kano, H., Horio, T., Takeda, T., Mandel, A.K. Ann. Intern. Med. (1995) [Pubmed]
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