High impact information on Cuminum

• In the antioxidant system, significant elevation of the specific activities of superoxide dismutase (P < 0.01) and catalase (P < 0.05) was observed with the 5% dose of cumin [1].
• Levels of cytochrome P-450 (cyt P-450) and cytochrome b5 (cyt b(5)) were significantly augmented (P < 0.05) by the 2.5% dose of cumin seed diet [1].
• The activities of glutathione peroxidase and glutathione reductase remained unaltered by both doses of cumin [1].
• Chemopreventive effects of Cuminum cyminum in chemically induced forestomach and uterine cervix tumors in murine model systems [1].
• The level of reduced glutathione measured as nonprotein sulfhydryl content was elevated (significance level being from P < 0.05 to P < 0.01) by both doses of cumin [1].

Biological context of Cuminum

• Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets [2].

Associations of Cuminum with chemical compounds

• Study of hypoglycaemic activity of Cuminum nigrum seeds in normal and alloxan diabetic rabbits [3].
• Antigenotoxic effects and changes in glutathione S-transferase (GST) activity were assessed in mice after oral co-administration of urethane (URE) with aqueous extracts of dietary vegetables (carrot, spinach and cabbage), spices (cinnamon, pepper, cumin, clove and cardamom), tea and coffee [4].
• The effect of feeding curcumin, capsaicin, ginger, mustard, black pepper and cumin on cholesterol and bile acid metabolism was studied in rats [5].
• Similar studies with extracts prepared from cumin (Cuminum cyminum) and turmeric (Curcuma longa) were undertaken [2].
• CONCLUSION: The present investigation shows that cumin prevents the changes in the composition of fatty acids, which were produced by ethanol and thermally oxidized oil [6].

Gene context of Cuminum

• Among the spices tested, cumin and fresh ginger made the most significant contribution to the antioxidant capacity [7].
• Cuminaldehyde: Aldose Reductase and alpha-Glucosidase Inhibitor Derived from Cuminum cyminum L. Seeds [8].
• Exposure to the odour of chocolate was associated with significant reductions in theta activity when compared with the odours of almond and cumin, with a trend towards significance when compared with no-odour control [9].
• Cumin, ginger and fenugreek also stimulated the levels of cytochrome P450 and cytochrome b5 and cumin and tamarind stimulated N-demethylase activity [10].

Analytical, diagnostic and therapeutic context of Cuminum

• Safrole was determined using gas-liquid chromatography in some common spices as star anise, cumin, black pepper and ginger [11].

References