Disease relevance of Tinospora

• The aqueous, alcoholic, and chloroform extracts of the leaves of Tinospora cordifolia were administered in doses of 50, 100, 150 and 200 mg/kg body weight to normal and alloxan-diabetic rabbits [1].
• Inhibitory effect of a polysaccharide from Tinospora cordifolia on experimental metastasis [2].
• Pretreatment with tinospora cordifolia or gentamicin reduced mortality in mice injected with 1 x 10(8) E. coli intraperitoneally from 100% in controls to 17.8% and 11.1% respectively [3].

High impact information on Tinospora

• Effect of Tinospora cordifolia on blood glucose and total lipid levels of normal and alloxan-diabetic rabbits [1].
• Enhanced production of the polysaccharide arabinogalactan using immobilized cultures of Tinospora cordifolia by elicitation and in situ adsorption [4].
• In this article we present evidence to show that an alcoholic extract of Tinospora cordifolia (ALTC) enhances the differentiation of TAM to dendritic cells (DC) in response to granulocyte/macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor [5].
• Immobilized callus cultures of Tinospora cordifolia (Willd) Miers ex Hooks and Thoms were investigated to find out the combined effect of elicitation, cell permeabilization with chitosan and in situ product recovery by polymeric neutral resin-like Diaion HP 20 [4].
• New lignan glucosides from the stems of Tinospora sinensis [6].

Chemical compound and disease context of Tinospora

• The effect of Tinospora cordifolia root extract was more potent than glibenclamide (600 microg/kg body weight) [7].

Anatomical context of Tinospora

• We have obtained evidence that co-incubation of thioglycollate-elicited peritoneal macrophages with an aqueous extract of Tinospora tuberculata inhibits lipopolysaccharide-stimulated excessive production of nitric oxide (NO) in vitro [8].

Associations of Tinospora with chemical compounds

• Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxan-induced diabetic rats [9].
• This report describes the isolation of two triterpenes from the stems of Tinospora crispa, namely, cycloeucalenol (1). and cycloeucalenone (2). for the first time [10].
• We present here the protective effects of an Indian medicinal plant Tinospora cordifolia as compared to gentamicin in E [3].
• The protective effects of Asparagus racemosus (AR) and Tinospora cordifolia (TC) against myelosuppression induced by single doses of cyclophosphamide (CP) have been previously reported [11].
• The water and ethanol extracts of stems of Tinospora cordifolia and T. sinensis inhibit immunosuppression produced by cyclophosphamide [12].

Gene context of Tinospora

• The ethanol extract of Tinospora smilacina showed inhibitory activities on COX-1, COX-2, 5-LO and PA(2) with the IC(50) values of 63.5, 81.2, 92.1 and 30.5 micro g/mL respectively [13].
• The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied [14].
• Efficacy of Tinospora cordifolia in allergic rhinitis [15].
• The optimal doses for MDP, Metronidazole, Asparagus racemosus and Tinospora cordifolia were found to be 100 micrograms, 300 mg/kg, 200 mg/kg and 100 mg/kg respectively [16].
• An alpha-D-glucan (RR1) composed of (1-->4) linked back bone and (1-->6) linked branches with a molecular mass of >550 kDa and exhibiting unique immune stimulating properties is isolated and characterized from the medicinal plant Tinospora cordifolia [17].

Analytical, diagnostic and therapeutic context of Tinospora

• We made an attempt to study the antioxidant properties of Tinospora cordifolia roots, an indigenous plant used in Ayurvedic medicine in India in alloxan diabetic rats [18].

References