High impact information on Sedum

• Malate decarboxylation in isolated mitochondria from the Crassulacean acid metabolism plant Sedum praealtum [1].
• Increase of glutathione in mine population of Sedum alfredii: a Zn hyperaccumulator and Pb accumulator [2].
• A first attempt to elucidate the polysaccharide-related anti-adhesive feature of Sedum juice was also performed [3].
• In-vitro antioxidant and in-vivo photoprotective effect of three lyophilized extracts of Sedum telephium L. leaves [4].
• The results confirmed that natural polysaccharides, with chemical structures different from heparin, were able to interfere with integrin-mediated cell behaviour and they contributed to the outstanding effects of Sedum juice and to the role of polysaccharides in cell-matrix interaction [3].

Biological context of Sedum

• Cell adhesion represents a primary event in wound repair and in tissue homeostasis, and therefore we have investigated the effect of Sedum juice and its main fractions, polysaccharides and flavonols, on human fibroblast (MRC5) adhesion to fibronectin and laminin [3].
• Using lipopolysaccharide-treated RAW 264.7 cells, down-regulation of cyclooxygenase-2 expression was found to be one of the cellular action mechanisms of anti-inflammation by Sedum kamtschaticum [5].

Associations of Sedum with chemical compounds

• Effects of Sedum oxipetalum ethanol extracts on human / mice epididymal sperm: motility, viability and structural changes [6].
• Characteristics of cadmium uptake and accumulation by two contrasting ecotypes of Sedum alfredii Hance [7].
• In addition, Sedum kamtschaticum exhibited potent analgesic activity against mouse acetic acid-induced writhing (IC50=125 mg/kg), while aspirin (200 mg/kg) showed 57% inhibition [5].
• Apollo larvae appeared to be quite specific in the plant choice and developed poorly in the absence of Sedum telephium [8].

References