Disease relevance of Keratectomy, Subepithelial, Laser-Assisted

• CONCLUSIONS: The long-term safety and effectiveness of LASEK for the correction of low to moderate myopia and astigmatism were demonstrated [1].
• CONCLUSIONS: Laser-assisted subepithelial keratectomy in children represents another method of providing long-term resolution of bilateral high myopia and myopic anisometropic amblyopia with minimal post-laser haze [2].
• PURPOSE: To assess and compare the clinical results (efficacy, safety, stability, and postoperative pain or discomfort) of laser-assisted subepithelial keratectomy (LASEK) and conventional photorefractive keratectomy (PRK) for the correction of low to moderate myopia [3].
• PURPOSE: To evaluate long-term results of custom laser epithelial keratomileusis (LASEK) for correction of myopia and hyperopia using the Custom Ablation Transition Zone (CATz) software and hyaluronic acid masking fluid (Laservis) for final corneal smoothing [4].

High impact information on Keratectomy, Subepithelial, Laser-Assisted

• OBJECTIVE: To evaluate the predictability and safety of hypertonic saline (5% sodium chloride) [correction]-assisted laser-assisted subepithelial keratectomy (HS-LASEK) vs 20% alcohol-assisted LASEK (A-LASEK) [5].
• METHODS: This retrospective analysis comprised 102 eyes that had LASEK for myopia using the Bausch & Lomb Technolas 217 excimer laser [6].
• PURPOSE: To evaluate the visual outcomes and complications in low to moderate levels of myopia and astigmatism treated with laser-assisted subepithelial keratectomy (LASEK) with a focus on postoperative recovery [1].
• Ethanol 20%, which is commonly used during laser-assisted subepithelial keratectomy, did not affect laser fluency [7].
• SETTING: Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. METHODS: In this prospective study, 19 patients with a manifest refraction of -3.00 to -8.25 diopters (D) were treated with LASEK using a conventional (6.0 mm) optical zone in 1 eye and a larger (6.5 mm) zone with 8.0 mm blend zone in the other eye [8].

Chemical compound and disease context of Keratectomy, Subepithelial, Laser-Assisted

• SETTING: Department of Ophthalmology, Yonsei University College of Medicine, and Balgeunsesang Ophthalmology Clinic, Seoul, Korea. METHODS: One hundred fifty-two eyes of 84 patients with myopia or myopic astigmatism were prospectively evaluated for 6 months after LASEK [9].

Anatomical context of Keratectomy, Subepithelial, Laser-Assisted

• Cleavage of corneal basement membrane components by ethanol exposure in laser-assisted subepithelial keratectomy [10].
• PURPOSE: Ethanol is used to loosen the corneal epithelium before photoablation in laser subepithelial keratomileusis (LASEK) [11].
• RESULTS: Findings in the transition zone between epithelium and anterior stroma in PRK and LASEK eyes were divided into two groups: Group 1, with marked hyper-reflectivity, and Group 2, with less hyper-reflectivity, similar to normal eyes [12].
• Laser epithelial keratomileusis (LASEK) is a surgical technique that may be performed in patients with low myopia who are considering conventional photorefractive keratectomy (PRK), in patients with thin corneas, and in patients with professions or lifestyles that predispose them to trauma [13].

Associations of Keratectomy, Subepithelial, Laser-Assisted with chemical compounds

• With this instrument set, ELSA (the laser-assisted subepithelial keratectomy [LASEK] described by Camellin) was performed in 34 astigmatic eyes [14].
• CONCLUSION: Our study highlights the efficacy of indomethacin solution compared with fluorometholon as a pain reducer after LASEK treatment and suggests that indomethacin is associated with a faster epithelial healing process [15].
• Corneal healing after LASEK surgery was equivalent for the antibiotic regimens containing moxifloxacin 0.5% ophthalmic solution and gatifloxacin 0.3% ophthalmic solution [16].
• A comparison of therapeutic regimens containing moxifloxacin 0.5% ophthalmic solution and gatifloxacin 0.3% ophthalmic solution for surgical prophylaxis in patients undergoing LASIK or LASEK [16].
• Fluorescein staining was increased 3 days and 1 week after LASEK [17].

Gene context of Keratectomy, Subepithelial, Laser-Assisted

• Coma-like and spherical-like aberrations changed similarly after both procedures, but spherical-like aberrations increased after LASEK with the 3.0 mm pupil (P<.05, independent t test) [18].
• METHODS: Laser-assisted subepithelial keratectomy was performed in 146 eyes of 83 consecutive patients with myopia or myopic astigmatism using a VISX Star S2 excimer laser (72 eyes) or a Nidek EC-5000 excimer laser (74 eyes) [19].
• CONCLUSION: We hypothesize that a more regular corneal surface, obtained with smoothing in PRK and LASEK, allows a better reparative response after refractive surgery [12].
• We calculated the release of TGF-beta1 (tear fluid flow-corrected concentrations of TGF-beta1) by multiplying the concentration by capillary tear fluid flow and also evaluated corneal haze at 1, 3, and 6 months after PRK or LASEK [20].
• LASIK, LASEK, CLE, PIOL, and CK appear to have bright futures, whereas, RK, ICR, and LTK are on the decline [21].

Analytical, diagnostic and therapeutic context of Keratectomy, Subepithelial, Laser-Assisted

• Laser in situ keratomileusis versus laser-assisted subepithelial keratectomy for the correction of high myopia [22].
• PURPOSE: To compare the effectiveness, safety, and stability of laser epithelial keratomileusis (LASEK), a modified photorefractive keratectomy (PRK) technique, with those of conventional PRK for low to moderate myopia [23].
• Tear film function and corneal sensation in the early postoperative period after LASEK for the correction of myopia [17].
• Mean spherical equivalent refraction after LASEK for low myopia in the MMC group at last examination (mean follow-up 312 days) was +0.50 +/- 0.93, and 0 +/- 0.34 D for the control group [24].
• METHODS: One hundred thirty-five patients undergoing LASEK, having been randomized in a double-masked manner into 2 groups (1 receiving indomethacin and 1 fluorometholon), were evaluated 2-4 days before and 4 days after treatment [15].

References