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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Protozoan Infections

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Disease relevance of Protozoan Infections

  • Unlike parasitic protozoan infection, C. albicans or A. fumigatus infection did not induce significant acute toxicity in IL-10-deficient mice, who, instead, showed reduced fungal burden and fungal-associated inflammatory responses [1].
  • Treatment with rifaximin (600 mg, 3 times a day, for 14 days) was efficacious in resolving the clinical symptoms and clearing protozoan infections in HIV-1 infected patients with CD4 > or = 200/mm3, who presented enteric and systemic symptoms due to Criptosporidium or Blastocystis associated with enteropathogenic bacteria [2].
  • The simultaneous presence of these 4 antigens was specific to the clinical disease and it was not detected in 47 sera from asymptomatic individuals living in the leishmaniasis endemic area of Alpes-Maritimes (southern France) or in 37 sera from patients with other protozoan infections [3].
  • The preeminent infectious threat to unwary tropical travelers, malaria is a preventable, mosquito-borne protozoan infection of red blood cells, which causes fever, anemia, respiratory failure, coma, and death [4].

Psychiatry related information on Protozoan Infections


High impact information on Protozoan Infections


Chemical compound and disease context of Protozoan Infections


Gene context of Protozoan Infections


  1. Antifungal type 1 responses are upregulated in IL-10-deficient mice. Del Sero, G., Mencacci, A., Cenci, E., d'Ostiani, C.F., Montagnoli, C., Bacci, A., Mosci, P., Kopf, M., Romani, L. Microbes Infect. (1999) [Pubmed]
  2. Intestinal protozoa in HIV-infected patients: effect of rifaximin in Cryptosporidium parvum and Blastocystis hominis infections. Amenta, M., Dalle Nogare, E.R., Colomba, C., Prestileo, T.S., Di Lorenzo, F., Fundaro, S., Colomba, A., Ferrieri, A. Journal of chemotherapy (Florence, Italy) (1999) [Pubmed]
  3. Detection by Western blot of four antigens characterizing acute clinical leishmaniasis due to Leishmania infantum. Marty, P., Lelièvre, A., Quaranta, J.F., Suffia, I., Eulalio, M., Gari-Toussaint, M., Le Fichoux, Y., Kubar, J. Trans. R. Soc. Trop. Med. Hyg. (1995) [Pubmed]
  4. Malaria. Stanley, J. Emerg. Med. Clin. North Am. (1997) [Pubmed]
  5. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. Campos, M.A., Almeida, I.C., Takeuchi, O., Akira, S., Valente, E.P., Procópio, D.O., Travassos, L.R., Smith, J.A., Golenbock, D.T., Gazzinelli, R.T. J. Immunol. (2001) [Pubmed]
  6. Allopurinol treatment for protozoan infections? Gunby, P. JAMA (1978) [Pubmed]
  7. MHC class II expression restricted to CD8alpha+ and CD11b+ dendritic cells is sufficient for control of Leishmania major. Lemos, M.P., Esquivel, F., Scott, P., Laufer, T.M. J. Exp. Med. (2004) [Pubmed]
  8. Caspase-8 activity prevents type 2 cytokine responses and is required for protective T cell-mediated immunity against Trypanosoma cruzi infection. Silva, E.M., Guillermo, L.V., Ribeiro-Gomes, F.L., De Meis, J., Pereira, R.M., Wu, Z., Calegari-Silva, T.C., Seabra, S.H., Lopes, U.G., Siegel, R.M., Dosreis, G.A., Lopes, M.F. J. Immunol. (2005) [Pubmed]
  9. Protection against progressive leishmaniasis by IFN-beta. Mattner, J., Wandersee-Steinhäuser, A., Pahl, A., Röllinghoff, M., Majeau, G.R., Hochman, P.S., Bogdan, C. J. Immunol. (2004) [Pubmed]
  10. Changes in C3 metabolism during protozoan infection (Babesia rodhaini) in rats. Chapman, W.E., Ward, P.A. J. Immunol. (1976) [Pubmed]
  11. Synthesis and characterization of N-demethylated metabolites of malachite green and leucomalachite green. Cho, B.P., Yang, T., Blankenship, L.R., Moody, J.D., Churchwell, M., Beland, F.A., Culp, S.J. Chem. Res. Toxicol. (2003) [Pubmed]
  12. Lymphocyte proliferation kinetics and sister-chromatid exchanges in individuals treated with metronidazole. Elizondo, G., Montero, R., Herrera, J.E., Hong, E., Ostrosky-Wegman, P. Mutat. Res. (1994) [Pubmed]
  13. Vitamin A and immunity to viral, bacterial and protozoan infections. Semba, R.D. The Proceedings of the Nutrition Society. (1999) [Pubmed]
  14. Dynamics of protozoan population density, plasma glutamic oxalacetic transaminase and plasma bilirubin concentrations during histomoniasis in turkeys. Hirsch, R.P. Int. J. Parasitol. (1979) [Pubmed]
  15. Influence of level, timing and duration of ronidazole water medication on histomoniasis in turkeys. Sullivan, T.W., Grace, O.D., Aksoy, A. Poult. Sci. (1977) [Pubmed]
  16. Concurrence of high levels of interferons alpha and beta in cord and maternal blood and simultaneous presence of interferon in trophoblast in an African population. Ebbesen, P., Hager, H., Nørskov-Lauritsen, N., Aboagye-Mathiesen, G., Zdravkovic, M., Villadsen, J., Liu, X., Petersen, P.M., Bambra, C., Nyongo, A. J. Interferon Cytokine Res. (1995) [Pubmed]
  17. Mig and IP-10: CXC chemokines that target lymphocytes. Farber, J.M. J. Leukoc. Biol. (1997) [Pubmed]
  18. Cytokines and immunological control of Eimeria spp. Ovington, K.S., Alleva, L.M., Kerr, E.A. Int. J. Parasitol. (1995) [Pubmed]
  19. Babesia bovis immunity. In vitro and in vivo evidence for IL-10 regulation of IFN-gamma and iNOS. Goff, W.L., Johnson, W.C., Cluff, C.W. Ann. N. Y. Acad. Sci. (1998) [Pubmed]
  20. Intracellular protozoan infection in small intestinal biopsies of patients with AIDS. Light and electron microscopic evaluation. Boldorini, R., Tosoni, A., Mazzucco, G., Cernuschi, M., Caramello, P., Maran, E., Costanzi, G., Monga, G. Pathol. Res. Pract. (1996) [Pubmed]
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