Disease relevance of Protozoan Infections

• Unlike parasitic protozoan infection, C. albicans or A. fumigatus infection did not induce significant acute toxicity in IL-10-deficient mice, who, instead, showed reduced fungal burden and fungal-associated inflammatory responses [1].
• Treatment with rifaximin (600 mg, 3 times a day, for 14 days) was efficacious in resolving the clinical symptoms and clearing protozoan infections in HIV-1 infected patients with CD4 > or = 200/mm3, who presented enteric and systemic symptoms due to Criptosporidium or Blastocystis associated with enteropathogenic bacteria [2].
• The simultaneous presence of these 4 antigens was specific to the clinical disease and it was not detected in 47 sera from asymptomatic individuals living in the leishmaniasis endemic area of Alpes-Maritimes (southern France) or in 37 sera from patients with other protozoan infections [3].
• The preeminent infectious threat to unwary tropical travelers, malaria is a preventable, mosquito-borne protozoan infection of red blood cells, which causes fever, anemia, respiratory failure, coma, and death [4].

Psychiatry related information on Protozoan Infections

• The activation of TLR-2 may initiate host innate defense mechanisms and inflammatory response during protozoan infection, and may provide new strategies for immune intervention during protozoan infections [5].

High impact information on Protozoan Infections

• Allopurinol treatment for protozoan infections [6]?
• Therefore, CD11b+ and CD8alpha+ DCs are not only key initiators of the primary response but also provide all the necessary cognate interactions for CD4+ T cell Th1 effectors to control this protozoan infection [7].
• These results suggest a critical role for caspase-8 in the establishment of T cell memory, cell signaling, and regulation of cytokine responses during protozoan infection [8].
• Type I IFNs (IFN-alphabeta) exert potent antiviral and immunoregulatory activities during viral infections, but their role in bacterial or protozoan infections is poorly understood [9].
• Changes in C3 metabolism during protozoan infection (Babesia rodhaini) in rats [10].

Chemical compound and disease context of Protozoan Infections

• Malachite green (MG), a triphenylmethane dye used to treat fungal and protozoan infections in fish, undergoes sequential oxidation to produce various N-demethylated derivatives (monodes-, dides(sym)-, dides(unsym)-, trides-, and tetrades-) both before and after reduction to leucomalachite green (LMG) [11].
• Metronidazole, an effective agent for the treatment of protozoan infections, is frequently used in developing countries [12].
• Vitamin A and immunity to viral, bacterial and protozoan infections [13].
• Dynamics of protozoan population density, plasma glutamic oxalacetic transaminase and plasma bilirubin concentrations during histomoniasis in turkeys [14].
• Influence of level, timing and duration of ronidazole water medication on histomoniasis in turkeys [15].

Gene context of Protozoan Infections

• Looking for IFN inducers, we did serologic tests for nonspecific indicators of inflammation and for specific virus and protozoan infections, but these showed no relation to elevated IFN levels [16].
• The genes for both MuMig and Crg-2 are highly expressed in multiple tissues during experimental viral and protozoan infections in mice, but their patterns of expression differ [17].
• Most attention has concentrated on interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) because these cytokines have been shown to limit other protozoan infections [18].
• Together, the data suggests that IL-10 and IFN-gamma are critical molecules involved in the response to this intraerythrocytic protozoan infection [19].
• Intracellular protozoan infection in small intestinal biopsies of patients with AIDS. Light and electron microscopic evaluation [20].

References