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Chemical Compound Review

SureCN896428     N-[(1R,2S)-2- phenylcyclopentyl]-1...

Synonyms: SureCN896431, SureCN7325923, KST-1A8696, AC1L3XHS, AC1Q4UQE, ...
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Disease relevance of Mdl 12330A


High impact information on Mdl 12330A


Biological context of Mdl 12330A

  • Furthermore, intrauterine injection of RMI-12330 A (50 microgram or 500 microgram/uterine horn), an inhibitor of adenylyl cyclases, on day 5 of pregnancy interrupted embryo development and implantation of the embryo [8].

Anatomical context of Mdl 12330A


Associations of Mdl 12330A with other chemical compounds


Gene context of Mdl 12330A


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  2. Heterosynaptic facilitation and behavioral sensitization are inhibited by lowering endogenous cAMP in Aplysia. Belardetti, F., Biondi, C., Brunelli, M., Fabri, M., Trevisani, A. Brain Res. (1983) [Pubmed]
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  5. Cyclic AMP signaling pathway modulates susceptibility of candida species and Saccharomyces cerevisiae to antifungal azoles and other sterol biosynthesis inhibitors. Jain, P., Akula, I., Edlind, T. Antimicrob. Agents Chemother. (2003) [Pubmed]
  6. 3,5,3'-Triiodothyronine increases cellular adenosine 3',5'-monophosphate concentration and sugar uptake in rat thymocytes by stimulating adenylate cyclase activity: studies with the adenylate cyclase inhibitor MDL 12330A. Segal, J., Ingbar, S.H. Endocrinology (1989) [Pubmed]
  7. Effects of RMI 12330A, a new inhibitor of adenylate cyclase on myocardial function and subcellular activity. Grupp, G., Grupp, I.L., Johnson, C.L., Matlib, M.A., Rouslin, W., Schwartz, A., Wallick, E.T., Wang, T., Wisler, P. Br. J. Pharmacol. (1980) [Pubmed]
  8. Role of histamine and cyclic nucleotides in implantation in the rabbit. Dey, S.K., Hubbard, C.J. Cell Tissue Res. (1981) [Pubmed]
  9. IC50 of trifluoperazine and RMI 12330A for the theophylline and phloretin-induced increase in intestinal D-galactose accumulation. Alcalde, A.I., Barcina, Y., Larralde, J., Ilundain, A. Rev. Esp. Fisiol. (1987) [Pubmed]
  10. A homogeneous enzyme fragment complementation cyclic AMP screen for GPCR agonists. Golla, R., Seethala, R. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. (2002) [Pubmed]
  11. Effect of growth hormone-releasing peptide-2 (GHRP-2) and GH-releasing hormone (GHRH) on the the cAMP levels and GH release from cultured acromegalic tumours. Chen, C., Pullar, M., Loneragan, K., Zhang, J., Clarke, I.J. J. Neuroendocrinol. (1998) [Pubmed]
  12. Circadian rhythm and photic control of cAMP level in chick retinal cell cultures: a mechanism for coupling the circadian oscillator to the melatonin-synthesizing enzyme, arylalkylamine N-acetyltransferase, in photoreceptor cells. Ivanova, T.N., Iuvone, P.M. Brain Res. (2003) [Pubmed]
  13. Inhibition of ADP-ribosyltransferase activity of cholera toxin by MDL 12330A and chlorpromazine. Bitonti, A.J. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
  14. Involvement of cyclic nucleotides and IP(3) in the regulation of luminescence in the brittlestar Amphipholis squamata (Echinodermata). De Bremaeker, N., Dewael, Y., Baguet, F., Mallefet, J. Luminescence : the journal of biological and chemical luminescence. (2000) [Pubmed]
  15. RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate cyclase in kidney preparations. Hunt, N.H., Evans, T. Biochim. Biophys. Acta (1980) [Pubmed]
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