Chemical Compound Review:
BAY-K-8644 methyl 2,6-dimethyl-5-nitro-4-[2...
Synonyms:
BayK8644, SureCN133106, B112_SIGMA, AG-J-73150, BAY-R 4407, ...
- Reduced L-type calcium current in the embryonic chick heart with persistent truncus arteriosus. Creazzo, T.L. Circ. Res. (1990)
- Maximal Ca2+-activated force elicited by tetanization of ferret papillary muscle and whole heart: mechanism and characteristics of steady contractile activation in intact myocardium. Marban, E., Kusuoka, H., Yue, D.T., Weisfeldt, M.L., Wier, W.G. Circ. Res. (1986)
- G protein specificity in receptor-effector coupling. Analysis of the roles of G0 and Gi2 in GH4C1 pituitary cells. Liu, Y.F., Jakobs, K.H., Rasenick, M.M., Albert, P.R. J. Biol. Chem. (1994)
- Canine left ventricular hypertrophy predisposes to ventricular tachycardia induction by phase 2 early afterdepolarizations after administration of BAY K 8644. Ben-David, J., Zipes, D.P., Ayers, G.M., Pride, H.P. J. Am. Coll. Cardiol. (1992)
- Inhibitory effects of D2 agonists by striatal injection on excessive release of dopamine and hyperactivity induced by Bay K 8644 in rats. Maruya, H., Watanabe, Y., Okita, M., Lawlor, G.F., Utsumi, H., Niitsuma, T. Neuroscience (2003)
- Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. García, A.G., Sala, F., Reig, J.A., Viniegra, S., Frías, J., Fontériz, R., Gandía, L. Nature (1984)
- Shaker-related potassium channel, Kv1.4, mRNA regulation in cultured rat heart myocytes and differential expression of Kv1.4 and Kv1.5 genes in myocardial development and hypertrophy. Matsubara, H., Suzuki, J., Inada, M. J. Clin. Invest. (1993)
- Patch-clamp evidence for calcium channels in apical membranes of rabbit kidney connecting tubules. Tan, S., Lau, K. J. Clin. Invest. (1993)
- Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunits. Sather, W.A., Tanabe, T., Zhang, J.F., Mori, Y., Adams, M.E., Tsien, R.W. Neuron (1993)
- Opposite central cardiovascular effects of nifedipine and BAY k 8644 in anesthetized rats. Laurent, S., Girerd, X., Tsoukaris-Kupfer, D., Legrand, M., Huchet-Brisac, A.M., Schmitt, H. Hypertension (1987)
- 45Ca uptake and the actions of Bay K 8644 on aortic strips from rabbits with perinephritis hypertension. Dong, Y., Wadsworth, R.M. J. Hypertens. (1987)
- Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment. Schettini, G., Meucci, O., Grimaldi, M., Florio, T., Landolfi, E., Scorziello, A., Ventra, C. J. Neurochem. (1991)
- Rhythm anomalies related to delayed repolarization in vivo: influence of sarcolemmal Ca++ entry and intracellular Ca++ overload. Carlsson, L., Drews, L., Duker, G. J. Pharmacol. Exp. Ther. (1996)
- Modulation of conduction slowing in ischemic rabbit myocardium by calcium-channel activation and blockade. Kabell, G. Circulation (1988)
- Purified skeletal muscle 1,4-dihydropyridine receptor forms phosphorylation-dependent oligomeric calcium channels in planar bilayers. Hymel, L., Striessnig, J., Glossmann, H., Schindler, H. Proc. Natl. Acad. Sci. U.S.A. (1988)
- A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent. Thomas, G., Chung, M., Cohen, C.J. Circ. Res. (1985)
- Effects of Bay k 8644, a dihydropyridine analog, on [3H]nitrendipine binding to canine cardiac sarcolemma and the relationship to a positive inotropic effect. Vaghy, P.L., Grupp, I.L., Grupp, G., Schwartz, A. Circ. Res. (1984)
- Cell cycle--dependent expression of L- and T-type Ca2+ currents in rat aortic smooth muscle cells in primary culture. Kuga, T., Kobayashi, S., Hirakawa, Y., Kanaide, H., Takeshita, A. Circ. Res. (1996)
- Direct contact between sympathetic neurons and rat cardiac myocytes in vitro increases expression of functional calcium channels. Ogawa, S., Barnett, J.V., Sen, L., Galper, J.B., Smith, T.W., Marsh, J.D. J. Clin. Invest. (1992)
- Mechanism of myocardial contractile depression by clinical concentrations of ethanol. A study in ferret papillary muscles. Guarnieri, T., Lakatta, E.G. J. Clin. Invest. (1990)
- Direct activation of second messenger pathways mimics cell adhesion molecule-dependent neurite outgrowth. Saffell, J.L., Walsh, F.S., Doherty, P. J. Cell Biol. (1992)
- Characterization of dihydropyridine-sensitive calcium channels in rat brain synaptosomes. Woodward, J.J., Cook, M.E., Leslie, S.W. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Inotropic and calcium kinetic effects of calcium channel agonist and antagonist in isolated cardiac myocytes from cardiomyopathic hamsters. Sen, L.Y., O'Neill, M., Marsh, J.D., Smith, T.W. Circ. Res. (1990)
- Modulation of severity of reperfusion stunning in the isolated rat heart by agents altering calcium flux at onset of reperfusion. du Toit, E.F., Opie, L.H. Circ. Res. (1992)
- Cellular mechanisms for synthesis and secretion of atrial natriuretic peptide and brain natriuretic peptide in cultured rat atrial cells. Suzuki, E., Hirata, Y., Kohmoto, O., Sugimoto, T., Hayakawa, H., Matsuoka, H., Sugimoto, T., Kojima, M., Kangawa, K., Minamino, N. Circ. Res. (1992)
- Alternans of action potential duration after abrupt shortening of cycle length: differences between dog Purkinje and ventricular muscle fibers. Saitoh, H., Bailey, J.C., Surawicz, B. Circ. Res. (1988)
- In vitro modulation of growth hormone (GH) secretion from early to midgestation human fetal pituitaries by GH-releasing factor and somatostatin: role of Gs-adenylate cyclase-Gi complex and Ca2+ channels. Goodyer, C.G., Branchaud, C.L., Lefebvre, Y. J. Clin. Endocrinol. Metab. (1993)
- The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II. Haisenleder, D.J., Ferris, H.A., Shupnik, M.A. Endocrinology (2003)
- Rapid corticosterone inhibition of corticotropin-releasing hormone binding and adrenocorticotropin release by enriched populations of corticotropes: counteractions by arginine vasopressin and its second messengers. Childs, G.V., Unabia, G. Endocrinology (1990)
- The intrinsic activity of (-)-3-PPP vis-à-vis prolactin-suppressing dopamine D2 receptors in transfected GH4C1 cells is dependent on which secretagogue that is used to provoke prolactin release. Nilsson, C.L., Hellstrand, M., Ekman, A., Eriksson, E. Neuropharmacology (1998)
- Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin. Tabrizchi, R., Triggle, C.R. J. Pharmacol. Exp. Ther. (1990)
- Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects. Satoh, H., Katoh, H., Velez, P., Fill, M., Bers, D.M. Circ. Res. (1998)
- Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity. Holz, G.G., Dunlap, K., Kream, R.M. J. Neurosci. (1988)
- Role of ATP-dependent K(+) channels in the electrical excitability of early embryonic stem cell-derived cardiomyocytes. Gryshchenko, O., Fischer, I.R., Dittrich, M., Viatchenko-Karpinski, S., Soest, J., Böhm-Pinger, M.M., Igelmund, P., Fleischmann, B.K., Hescheler, J. J. Cell. Sci. (1999)
- Contractions of dysgenic skeletal muscle triggered by a potentiated, endogenous calcium current. Adams, B.A., Beam, K.G. J. Gen. Physiol. (1991)