Disease relevance of ZINC PHOSPHIDE

• Persistent severe hypoglycemia in acute zinc phosphide poisoning [1].
• The objective of this case report was to determine whether the sudden death described in these chickens was caused by the ingestion of zinc phosphide, by developing a sensitive and highly specific gas chromatography/mass spectrometry (GC/MS) methodology for analysis of the gastrointestinal samples submitted to the laboratory [2].
• The results reveal influence of dietary protein in modulating the toxicity of zinc phosphide, suggesting that greater caution should be exercised while formulating its baits for effectiveness [3].
• Acute pancreatitis due to zinc phosphide ingestion [4].
• Organophosphorus compounds (42%), drugs (25%), and zinc phosphide (6.5%) were common poisonings in total and in adult populations, whereas kerosene was the most frequent poisoning in pediatric age group [5].

High impact information on ZINC PHOSPHIDE

• Phosphine (PH(3)), from hydrolysis of aluminum, magnesium and zinc phosphide, is an insecticide and rodenticide [6].
• It was also found that the determination of zinc concentrations in liver or kidney tissue or stomach contents is not a reliable indicator of zinc phosphide poisoning [2].
• Diagnosis of zinc phosphide poisoning has previously been based on history of exposure, identification of the bait material in the gastrointestinal tract, and chemical detection of phosphine gas [2].
• Neuropsychiatric syndromes and occupational exposure to zinc phosphide in Egypt [7].
• CONCLUSION: We suggest that rodent control operations using zinc phosphide be done within a 500-meter circle of houses once every two years before the beginning of the active season of sandflies, which begins in late April [8].

Chemical compound and disease context of ZINC PHOSPHIDE

• As examples, veterinarians have had to manage companion animal poisonings due to anticoagulant, sodium fluoroacetate (compound 1080), thallium, barium carbonate, and zinc phosphide-based rodenticides [9].

Biological context of ZINC PHOSPHIDE

• The genotoxic potential of zinctox (zinc phosphide) was evaluated in mice in vivo employing different bioassays: bone marrow chromosome aberration, micronucleus and sperm shape abnormality [10].

Anatomical context of ZINC PHOSPHIDE

• Zinc phosphide at both tested concentrations of 0.6 and 6 ppm was ineffective on the abortion and resorption of fetuses; the fed females on baits containing 0.6 and/or 6.0 ppm zinc phosphide ate their youngsters at the 2nd and 4th day after birth, respectively [11].

Associations of ZINC PHOSPHIDE with other chemical compounds

• The cost-benefit ratio of the employed rodenticides favoured zinc phosphide than bromadiolone [12].

Analytical, diagnostic and therapeutic context of ZINC PHOSPHIDE

• Laboratory diagnosis of zinc phosphide poisoning [13].
• Epidemiological study of the claimed zinc phosphide intoxication in Kom Ombo district april 1996 [14].
• Zinc phosphide was identified using microscopic examination, scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDX) and X-ray powder diffraction (XRD) [15].

References