Chemical Compound Review:
AC1L4VNW 3-acetamido-5-(ethanoyl- methyl-amino)-2,4...
Synonyms:
AC1Q4PBE, AR-1C5894, A823048
Zhao,
Huang,
Liu,
Wang,
Zhong,
Xiao,
Hu,
Li,
Parmee,
Brockunier,
He,
Singh,
Candelore,
Cascieri,
Deng,
Liu,
Tota,
Wyvratt,
Fisher,
Weber,
Natarajan,
Doherty,
Frankish,
Farrell,
Sheridan,
de Dios,
Shih,
López de Uralde,
Sánchez,
del Prado,
Martín Cabrejas,
Pleite,
Blanco-Urgoiti,
Lorite,
Nevill,
Bonjouklian,
York,
Vieth,
Wang,
Magnus,
Campbell,
Anderson,
McCann,
Giera,
Lee,
Schultz,
Li,
Johnson,
Wolos,
- Synthesis and antiviral activity of helioxanthin analogues. Yeo, H., Li, Y., Fu, L., Zhu, J.L., Gullen, E.A., Dutschman, G.E., Lee, Y., Chung, R., Huang, E.S., Austin, D.J., Cheng, Y.C. J. Med. Chem. (2005)
- Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret. Duplantier, A.J., Biggers, M.S., Chambers, R.J., Cheng, J.B., Cooper, K., Damon, D.B., Eggler, J.F., Kraus, K.G., Marfat, A., Masamune, H., Pillar, J.S., Shirley, J.T., Umland, J.P., Watson, J.W. J. Med. Chem. (1996)
- Structure-based design and synthesis of substituted 2-butanols as nonpeptidic inhibitors of HIV protease: secondary amide series. Reich, S.H., Melnick, M., Pino, M.J., Fuhry, M.A., Trippe, A.J., Appelt, K., Davies, J.F., Wu, B.W., Musick, L. J. Med. Chem. (1996)
- 5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities. Gangjee, A., Patel, J., Kisliuk, R.L., Gaumont, Y. J. Med. Chem. (1992)
- Synthesis, molecular structure, and in vitro antitumor activity of new 4-chloro-2-mercaptobenzenesulfonamide derivatives. Sławiński, J., Gdaniec, M. European journal of medicinal chemistry. (2005)
- FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates. Zhao, L., Huang, W., Liu, H., Wang, L., Zhong, W., Xiao, J., Hu, Y., Li, S. J. Med. Chem. (2006)
- Design of potent and selective 2-aminobenzimidazole-based p38alpha MAP kinase inhibitors with excellent in vivo efficacy. de Dios, A., Shih, C., López de Uralde, B., Sánchez, C., del Prado, M., Martín Cabrejas, L.M., Pleite, S., Blanco-Urgoiti, J., Lorite, M.J., Nevill, C.R., Bonjouklian, R., York, J., Vieth, M., Wang, Y., Magnus, N., Campbell, R.M., Anderson, B.D., McCann, D.J., Giera, D.D., Lee, P.A., Schultz, R.M., Li, L.C., Johnson, L.M., Wolos, J.A. J. Med. Chem. (2005)
- Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A. Baraldi, P.G., Romagnoli, R., Beria, I., Cozzi, P., Geroni, C., Mongelli, N., Bianchi, N., Mischiati, C., Gambari, R. J. Med. Chem. (2000)
- Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. Högberg, M., Sahlberg, C., Engelhardt, P., Noréen, R., Kangasmetsä, J., Johansson, N.G., Oberg, B., Vrang, L., Zhang, H., Sahlberg, B.L., Unge, T., Lövgren, S., Fridborg, K., Bäckbro, K. J. Med. Chem. (1999)
- Improved P1/P1' substituents for cyclic urea based HIV-1 protease inhibitors: synthesis, structure-activity relationship, and X-ray crystal structure analysis. Nugiel, D.A., Jacobs, K., Cornelius, L., Chang, C.H., Jadhav, P.K., Holler, E.R., Klabe, R.M., Bacheler, L.T., Cordova, B., Garber, S., Reid, C., Logue, K.A., Gorey-Feret, L.J., Lam, G.N., Erickson-Viitanen, S., Seitz, S.P. J. Med. Chem. (1997)
- Derivatives of 2-[[N-(Aminocarbonyl)-N-hydroxyamino]methyl]-1,4- benzodioxan as orally active 5-lipoxygenase inhibitors. Satoh, Y., Powers, C., Toledo, L.M., Kowalski, T.J., Peters, P.A., Kimble, E.F. J. Med. Chem. (1995)
- Nonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: profile of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1' -biphenyl]-4-yl]-methyl]-4-[2-(trifluoroacetyl)-1H-pyrrol-1-yl]-1H- imidazole-5-carboxylic acid (CI-996). Sircar, I., Hodges, J.C., Quin, J., Bunker, A.M., Winters, R.T., Edmunds, J.J., Kostlan, C.R., Connolly, C., Kesten, S.J., Hamby, J.M. J. Med. Chem. (1993)
- Pseudopeptide inhibitors of Ras farnesyl-protein transferase. Graham, S.L., deSolms, S.J., Giuliani, E.A., Kohl, N.E., Mosser, S.D., Oliff, A.I., Pompliano, D.L., Rands, E., Breslin, M.J., Deana, A.A. J. Med. Chem. (1994)
- Synthesis of 3'-deoxy-3'-difluoromethyl azanucleosides from trans-4-hydroxy-l-proline. Qiu, X.L., Qing, F.L. J. Org. Chem. (2005)
- Stereoselective synthesis of 7,11-guaien-8,12-olides from santonin. Synthesis of podoandin and (+)-zedolactone A. Blay, G., Bargues, V., Cardona, L., García, B., Pedro, J.R. J. Org. Chem. (2000)
- Congener derivatives and conjugates of histamine: synthesis and tissue and receptor selectivity of the derivatives. Khan, M.M., Melmon, K.L., Marr-Leisy, D., Verlander, M.S., Egli, M., Lok, S., Goodman, M. J. Med. Chem. (1987)
- Synthesis and sulfatase inhibitory activities of non-steroidal estrone sulfatase inhibitors. Li, P.K., Milano, S., Kluth, L., Rhodes, M.E. J. Steroid Biochem. Mol. Biol. (1996)
- Investigation into the mast cell stabilizing activity of nature-identical and synthetic indanones. Frankish, N., Farrell, R., Sheridan, H. J. Pharm. Pharmacol. (2004)
- Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists. Parmee, E.R., Brockunier, L.L., He, J., Singh, S.B., Candelore, M.R., Cascieri, M.A., Deng, L., Liu, Y., Tota, L., Wyvratt, M.J., Fisher, M.H., Weber, A.E. Bioorg. Med. Chem. Lett. (2000)
- P38 MAP kinase inhibitors: evolution of imidazole-based and pyrido-pyrimidin-2-one lead classes. Natarajan, S.R., Doherty, J.B. Current topics in medicinal chemistry. (2005)
- Investigation of the effect of varying the 4-anilino and 7-alkoxy groups of 3-quinolinecarbonitriles on the inhibition of Src kinase activity. Boschelli, D.H., Ye, F., Wu, B., Wang, Y.D., Barrios Sosa, A.C., Yaczko, D., Powell, D., Golas, J.M., Lucas, J., Boschelli, F. Bioorg. Med. Chem. Lett. (2003)









