Gene Review:
EEF1B2P2 - eukaryotic translation elongation factor 1...
Homo sapiens
Synonyms:
BETA-3, EEF-1, EEF-1BETA5A, EEF1B, EEF1B3
- Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Brooks, P.C., Strömblad, S., Sanders, L.C., von Schalscha, T.L., Aimes, R.T., Stetler-Stevenson, W.G., Quigley, J.P., Cheresh, D.A. Cell (1996)
- The linkage arrangement of four rabbit beta-like globin genes. Lacy, E., Hardison, R.C., Quon, D., Maniatis, T. Cell (1979)
- Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Wickham, T.J., Mathias, P., Cheresh, D.A., Nemerow, G.R. Cell (1993)
- Mutations in the gene encoding gap junction protein beta-3 associated with autosomal dominant hearing impairment. Xia, J.H., Liu, C.Y., Tang, B.S., Pan, Q., Huang, L., Dai, H.P., Zhang, B.R., Xie, W., Hu, D.X., Zheng, D., Shi, X.L., Wang, D.A., Xia, K., Yu, K.P., Liao, X.D., Feng, Y., Yang, Y.F., Xiao, J.Y., Xie, D.H., Huang, J.Z. Nat. Genet. (1998)
- Further characterization of the thrombasthenia-related idiotype OG. Antiidiotype defines a novel epitope(s) shared by fibrinogen B beta chain, vitronectin, and von Willebrand factor and required for binding to beta 3. Gruel, Y., Brojer, E., Nugent, D.J., Kunicki, T.J. J. Exp. Med. (1994)
- Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Götz, J., Chen, F., van Dorpe, J., Nitsch, R.M. Science (2001)
- beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes. Eizirik, D.L., Darville, M.I. Diabetes (2001)
- Oscillatory Beta Activity Predicts Response Speed during a Multisensory Audiovisual Reaction Time Task: A High-Density Electrical Mapping Study. Senkowski, D., Molholm, S., Gomez-Ramirez, M., Foxe, J.J. Cereb. Cortex (2006)
- Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation. Gotti, C., Moretti, M., Bohr, I., Ziabreva, I., Vailati, S., Longhi, R., Riganti, L., Gaimarri, A., McKeith, I.G., Perry, R.H., Aarsland, D., Larsen, J.P., Sher, E., Beattie, R., Clementi, F., Court, J.A. Neurobiol. Dis. (2006)
- Antiobesity and antidiabetic beta-agonists: lessons learned and questions to be answered. Yen, T.T. Obes. Res. (1994)
- Structural basis of integrin activation by talin. Wegener, K.L., Partridge, A.W., Han, J., Pickford, A.R., Liddington, R.C., Ginsberg, M.H., Campbell, I.D. Cell (2007)
- Association of a human G-protein beta3 subunit variant with hypertension. Siffert, W., Rosskopf, D., Siffert, G., Busch, S., Moritz, A., Erbel, R., Sharma, A.M., Ritz, E., Wichmann, H.E., Jakobs, K.H., Horsthemke, B. Nat. Genet. (1998)
- Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution. LaSalle, J.M., Lalande, M. Nat. Genet. (1995)
- alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen. Godefroy, E., Moreau-Aubry, A., Diez, E., Dreno, B., Jotereau, F., Guilloux, Y. J. Exp. Med. (2005)
- Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization. Wickham, T.J., Filardo, E.J., Cheresh, D.A., Nemerow, G.R. J. Cell Biol. (1994)
- The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel. Newman, P.J., Seligsohn, U., Lyman, S., Coller, B.S. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Concordance between isolated cleft palate in mice and alterations within a region including the gene encoding the beta 3 subunit of the type A gamma-aminobutyric acid receptor. Culiat, C.T., Stubbs, L., Nicholls, R.D., Montgomery, C.S., Russell, L.B., Johnson, D.K., Rinchik, E.M. Proc. Natl. Acad. Sci. U.S.A. (1993)
- A Leu117-->Trp mutation within the RGD-peptide cross-linking region of beta3 results in Glanzmann thrombasthenia by preventing alphaIIb beta3 export to the platelet surface. Basani, R.B., Brown, D.L., Vilaire, G., Bennett, J.S., Poncz, M. Blood (1997)
- Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa). Du, X.P., Plow, E.F., Frelinger, A.L., O'Toole, T.E., Loftus, J.C., Ginsberg, M.H. Cell (1991)
- Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Brooks, P.C., Montgomery, A.M., Rosenfeld, M., Reisfeld, R.A., Hu, T., Klier, G., Cheresh, D.A. Cell (1994)
- A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Nakatsu, Y., Tyndale, R.F., DeLorey, T.M., Durham-Pierre, D., Gardner, J.M., McDanel, H.J., Nguyen, Q., Wagstaff, J., Lalande, M., Sikela, J.M. Nature (1993)
- Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Lawson, M.A., Maxfield, F.R. Nature (1995)
- Expression of transforming growth factor beta 3 in hypertrophic juxtaglomerular apparatus. Ray, P.E., McCune, B.K., Gomez, R.A., Ruley, E.J., Klotman, P.E. N. Engl. J. Med. (1994)
- High-affinity binding of staphylococcal enterotoxins A and B to HLA-DR. Fraser, J.D. Nature (1989)
- Vascular adrenoceptors: an update. Guimarães, S., Moura, D. Pharmacol. Rev. (2001)
- Ligand and cation binding are dual functions of a discrete segment of the integrin beta 3 subunit: cation displacement is involved in ligand binding. D'Souza, S.E., Haas, T.A., Piotrowicz, R.S., Byers-Ward, V., McGrath, D.E., Soule, H.R., Cierniewski, C., Plow, E.F., Smith, J.W. Cell (1994)
- Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse. Chavis, P., Westbrook, G. Nature (2001)
- Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. King, K., Dohlman, H.G., Thorner, J., Caron, M.G., Lefkowitz, R.J. Science (1990)
- Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. Akimov, S.S., Krylov, D., Fleischman, L.F., Belkin, A.M. J. Cell Biol. (2000)
- Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of alpha IIb beta 3 engagement. Mekrache, M., Bachelot-Loza, C., Ajzenberg, N., Saci, A., Legendre, P., Baruch, D. Blood (2003)
- CD36 associates with CD9 and integrins on human blood platelets. Miao, W.M., Vasile, E., Lane, W.S., Lawler, J. Blood (2001)
- Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src). Lebrun, P., Mothe-Satney, I., Delahaye, L., Van Obberghen, E., Baron, V. J. Biol. Chem. (1998)
- Integrin-linked kinase regulates vascular morphogenesis induced by vascular endothelial growth factor. Kaneko, Y., Kitazato, K., Basaki, Y. J. Cell. Sci. (2004)
- Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor. Ling, Y., Maile, L.A., Clemmons, D.R. Mol. Endocrinol. (2003)
- Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration. Udayakumar, T.S., Chen, M.L., Bair, E.L., Von Bredow, D.C., Cress, A.E., Nagle, R.B., Bowden, G.T. Cancer Res. (2003)
- Differential regulation of protein-tyrosine phosphatases by integrin alpha IIb beta 3 through cytoskeletal reorganization and tyrosine phosphorylation in human platelets. Ezumi, Y., Takayama, H., Okuma, M. J. Biol. Chem. (1995)
- A well-defined in vitro three-dimensional culture of human endometrium and its applicability to endometrial cancer invasion. Park, D.W., Choi, D.S., Ryu, H.S., Kwon, H.C., Joo, H., Min, C.K. Cancer Lett. (2003)
- CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism. André, P., Prasad, K.S., Denis, C.V., He, M., Papalia, J.M., Hynes, R.O., Phillips, D.R., Wagner, D.D. Nat. Med. (2002)
- CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth. Babic, A.M., Kireeva, M.L., Kolesnikova, T.V., Lau, L.F. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis. Fitzgerald, J.E., Ricalton, N.S., Meyer, A.C., West, S.G., Kaplan, H., Behrendt, C., Kotzin, B.L. J. Immunol. (1995)
- Autocrine TGF-beta-regulated expression of adhesion receptors and integrin-linked kinase in HT-144 melanoma cells correlates with their metastatic phenotype. Janji, B., Melchior, C., Gouon, V., Vallar, L., Kieffer, N. Int. J. Cancer (1999)
- Activation of integrin receptors is required for growth factor-induced smooth muscle cell dysfunction. Mawatari, K., Liu, B., Kent, K.C. J. Vasc. Surg. (2000)
- Comparative genomic analysis of genes encoding translation elongation factor 1B(alpha) in human and mouse shows EEF1B1 to be a recent retrotransposition event. Chambers, D.M., Rouleau, G.A., Abbott, C.M. Genomics (2001)
- Allele specificity of DNA replication timing in the Angelman/Prader-Willi syndrome imprinted chromosomal region. Knoll, J.H., Cheng, S.D., Lalande, M. Nat. Genet. (1994)
- Endoglin modulates cellular responses to TGF-beta 1. Lastres, P., Letamendía, A., Zhang, H., Rius, C., Almendro, N., Raab, U., López, L.A., Langa, C., Fabra, A., Letarte, M., Bernabéu, C. J. Cell Biol. (1996)
- Thrombospondin modulates alpha v beta 3 function through integrin-associated protein. Gao, A.G., Lindberg, F.P., Dimitry, J.M., Brown, E.J., Frazier, W.A. J. Cell Biol. (1996)
- In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa. Robbins, P.B., Lin, Q., Goodnough, J.B., Tian, H., Chen, X., Khavari, P.A. Proc. Natl. Acad. Sci. U.S.A. (2001)
- A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells. Cheresh, D.A., Smith, J.W., Cooper, H.M., Quaranta, V. Cell (1989)
- Endoluminal beta-radiation therapy for the prevention of coronary restenosis after balloon angioplasty. The Dose-Finding Study Group. Verin, V., Popowski, Y., de Bruyne, B., Baumgart, D., Sauerwein, W., Lins, M., Kovacs, G., Thomas, M., Calman, F., Disco, C., Serruys, P.W., Wijns, W. N. Engl. J. Med. (2001)
- Effect of carvedilol on survival in severe chronic heart failure. Packer, M., Coats, A.J., Fowler, M.B., Katus, H.A., Krum, H., Mohacsi, P., Rouleau, J.L., Tendera, M., Castaigne, A., Roecker, E.B., Schultz, M.K., DeMets, D.L. N. Engl. J. Med. (2001)
- Coordinate and selective beta-tubulin gene expression associated with cilium formation in sea urchin embryos. Harlow, P., Nemer, M. Genes Dev. (1987)