Chemical Compound Review:
AC1MHUWT 2-[4-[(E)-1,2-diphenylbut-1- enyl]phenoxy]...
Synonyms:
LS-68203, ICI 55,548, AC1Q56SZ, 31750-48-8, Desmethyltamoxifen, ...
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- Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens. Santner, S.J., Santen, R.J. J. Steroid Biochem. Mol. Biol. (1993)
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- DNA cleavage and 8-hydroxydeoxyguanosine formation caused by tamoxifen derivatives in vitro. Okubo, T., Nagai, F., Ushiyama, K., Yokoyama, Y., Ozawa, S., Kano, K., Tomita, S., Kubo, H., Kano, I. Cancer Lett. (1998)
- The steady-state pharmacokinetics of tamoxifen and its metabolites in breast cancer patients. Soininen, K., Kleimola, T., Elomaa, I., Salmo, M., Rissanen, P. J. Int. Med. Res. (1986)
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- Analysis of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen levels in cytosol and KCl-nuclear extracts of breast tumours from tamoxifen treated patients by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). Murphy, C., Fotsis, T., Pantzar, P., Adlercreutz, H., Martin, F. J. Steroid Biochem. (1987)
- Interactions of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen with P-glycoprotein and CYP3A. Bekaii-Saab, T.S., Perloff, M.D., Weemhoff, J.L., Greenblatt, D.J., von Moltke, L.L. Biopharmaceutics & drug disposition. (2004)
- Antiestrogens and steroid hormones: substrates of the human P-glycoprotein. Rao, U.S., Fine, R.L., Scarborough, G.A. Biochem. Pharmacol. (1994)
- Influence of polyethylene glycol and acetone on the in vitro biotransformation of tamoxifen and alprazolam by human liver microsomes. Cotreau-Bibbo, M.M., von Moltke, L.L., Greenblatt, D.J. Journal of pharmaceutical sciences. (1996)
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- Oestrogenic activity of tamoxifen and its metabolites on gene regulation and cell proliferation in MCF-7 breast cancer cells. Johnson, M.D., Westley, B.R., May, F.E. Br. J. Cancer (1989)
- Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts. Davies, A.M., Martin, E.A., Jones, R.M., Lim, C.K., Smith, L.L., White, I.N. Carcinogenesis (1995)