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Chemical Compound Review

SULFOMETURON     2-[(4,6-dimethylpyrimidin-2...

Synonyms: SureCN66180, CHEMBL401913, LS-37252, BRN 0937935, AC1L1E19, ...
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Disease relevance of BRN 0937935


High impact information on BRN 0937935


Biological context of BRN 0937935


Associations of BRN 0937935 with other chemical compounds


Gene context of BRN 0937935

  • Chimaeric genes were constructed containing the 5' upstream and partial coding sequence of SMR1--a sulfometuron methyl resistant allele of the ILV2 locus [10].
  • During preconcentration by CFLME, five target compounds, including metsulfuron methyl, bensulfuron methyl, tribenuron methyl, sulfometuron methyl, and ethametsulfuron, were enriched in 960 microl of 0.5 mol l(-1) Na2CO3-NaHCO3 (pH 10.8) buffer used as acceptor [11].
  • Sulfometuron was detected in streamflow at low levels up to 29 days after treatment (DAT) on the watershed treated with the 75% dispersible granule formulation (Oust; DuPont Chemical Company, Wilmington, DE) and less than 53 DAT on the watershed treated with the experimental formulation (1% pellet) [12].

Analytical, diagnostic and therapeutic context of BRN 0937935


  1. ilvB-encoded acetolactate synthase is resistant to the herbicide sulfometuron methyl. LaRossa, R.A., Smulski, D.R. J. Bacteriol. (1984) [Pubmed]
  2. Involvement of ack-pta operon products in alpha-ketobutyrate metabolism by Salmonella typhimurium. Van Dyk, T.K., LaRossa, R.A. Mol. Gen. Genet. (1987) [Pubmed]
  3. The sulfonylurea herbicide sulfometuron methyl is an extremely potent and selective inhibitor of acetolactate synthase in Salmonella typhimurium. LaRossa, R.A., Schloss, J.V. J. Biol. Chem. (1984) [Pubmed]
  4. Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase. Falco, S.C., Dumas, K.S., Livak, K.J. Nucleic Acids Res. (1985) [Pubmed]
  5. Genetic analysis of mutants of Saccharomyces cerevisiae resistant to the herbicide sulfometuron methyl. Falco, S.C., Dumas, K.S. Genetics (1985) [Pubmed]
  6. Molecular cloning of an arabidopsis homologue of GCN2, a protein kinase involved in co-ordinated response to amino acid starvation. Zhang, Y., Dickinson, J.R., Paul, M.J., Halford, N.G. Planta (2003) [Pubmed]
  7. Genetic engineering of a sake yeast producing no urea by successive disruption of arginase gene. Kitamoto, K., Oda, K., Gomi, K., Takahashi, K. Appl. Environ. Microbiol. (1991) [Pubmed]
  8. Rapid physical mapping by transposon Tn5 mutagenesis to localize the cloned yeast ILV2 gene. Van Dyk, T.K., Falco, S.C., LaRossa, R.A. Appl. Environ. Microbiol. (1986) [Pubmed]
  9. Capillary electrophoretic behavior of seven sulfonylureas. Matchett, W.H., Winnik, W., Brumley, W.C. Journal of capillary electrophoresis. (1996) [Pubmed]
  10. Generation of an ilv bradytrophic phenocopy in yeast by antisense RNA. Xiao, W., Rank, G.H. Curr. Genet. (1988) [Pubmed]
  11. Trace analysis of sulfonylurea herbicides in water by on-line continuous flow liquid membrane extraction--C18 precolumn liquid chromatography with ultraviolet absorbance detection. Liu, J.F., Chao, J.B., Jiang, G.B., Cai, Y.Q., Liu, J.M. Journal of chromatography. A. (2003) [Pubmed]
  12. Environmental fate and impacts of sulfometuron on watersheds in the southern United States. Michael, J.L. J. Environ. Qual. (2003) [Pubmed]
  13. Molecular cloning of a novel allele of SMR1 which determines sulfometuron methyl resistance in Saccharomyces cerevisiae. Xie, Q., Jiménez, A. FEMS Microbiol. Lett. (1996) [Pubmed]
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