Chemical Compound Review:
Acetolactate 2-acetyloxypropanoic acid
Synonyms:
ACMC-209mjg, NSC-402126, AC1L2WIV, ACT03849, CTK1C1202, ...
- Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity. Nemeria, N., Tittmann, K., Joseph, E., Zhou, L., Vazquez-Coll, M.B., Arjunan, P., Hübner, G., Furey, W., Jordan, F. J. Biol. Chem. (2005)
- The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate. Pang, S.S., Duggleby, R.G., Schowen, R.L., Guddat, L.W. J. Biol. Chem. (2004)
- Regulation by external pH and stationary growth phase of the acetolactate synthase from Synechocystis PCC6803. Maestri, O., Joset, F. Mol. Microbiol. (2000)
- Purification and properties of Salmonella typhimurium acetolactate synthase isozyme II from Escherichia coli HB101/pDU9. Schloss, J.V., Van Dyk, D.E., Vasta, J.F., Kutny, R.M. Biochemistry (1985)
- Degradative acetolactate synthase of Bacillus subtilis: purification and properties. Holtzclaw, W.D., Chapman, L.F. J. Bacteriol. (1975)
- Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate. Marobbio, C.M., Vozza, A., Harding, M., Bisaccia, F., Palmieri, F., Walker, J.E. EMBO J. (2002)
- Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase. Falco, S.C., Dumas, K.S., Livak, K.J. Nucleic Acids Res. (1985)
- Molecular analysis of the acetolactate synthase gene of Chlamydomonas reinhardtii and development of a genetically engineered gene as a dominant selectable marker for genetic transformation. Kovar, J.L., Zhang, J., Funke, R.P., Weeks, D.P. Plant J. (2002)
- Regulation of tobacco acetolactate synthase gene expression. Keeler, S.J., Sanders, P., Smith, J.K., Mazur, B.J. Plant Physiol. (1993)
- Kinetics and mechanism of acetohydroxy acid synthase isozyme III from Escherichia coli. Gollop, N., Damri, B., Barak, Z., Chipman, D.M. Biochemistry (1989)
- Acetohydroxy acid synthase activity from a mutation at ilvF in Escherichia coli K-12. Alexander-Caudle, C., Latinwo, L.M., Jackson, J.H. J. Bacteriol. (1990)
- Toxic accumulation of alpha-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium. LaRossa, R.A., Van Dyk, T.K., Smulski, D.R. J. Bacteriol. (1987)
- Metabolic interlock between the acetolactate synthase isoenzymes and lysine biosynthesis in Escherichia coli K-12. De Felice, M., Guardiola, J., Schreil, W., Levinthal, M., Iaccarino, M. Mol. Gen. Genet. (1977)
- Effect of inactivation of nuo and ackA-pta on redistribution of metabolic fluxes in Escherichia coli. Yang, Y.T., Bennett, G.N., San, K.Y. Biotechnol. Bioeng. (1999)
- Binding and activation of thiamin diphosphate in acetohydroxyacid synthase. Bar-Ilan, A., Balan, V., Tittmann, K., Golbik, R., Vyazmensky, M., Hübner, G., Barak, Z., Chipman, D.M. Biochemistry (2001)
- Alkylation of acetohydroxyacid synthase I from Escherichia coli K-12 by 3-bromopyruvate: evidence for a single active site catalyzing acetolactate and acetohydroxybutyrate synthesis. Silverman, P.M., Eoyang, L. J. Bacteriol. (1987)
- Cloning, sequencing and heterologous expression of a Klebsiella pneumoniae gene encoding an FAD-independent acetolactate synthase. Peng, H.L., Wang, P.Y., Wu, C.M., Hwang, D.C., Chang, H.Y. Gene (1992)
- Transcriptional and Metabolic Responses of Bacillus subtilis to the Availability of Organic Acids: Transcription Regulation Is Important but Not Sufficient To Account for Metabolic Adaptation. Schilling, O., Frick, O., Herzberg, C., Ehrenreich, A., Heinzle, E., Wittmann, C., St??lke, J. Appl. Environ. Microbiol. (2007)
- Protein trans-splicing to produce herbicide-resistant acetolactate synthase. Sun, L., Ghosh, I., Paulus, H., Xu, M.Q. Appl. Environ. Microbiol. (2001)
- Purification and properties of Saccharomyces cerevisiae acetolactate synthase from recombinant Escherichia coli. Poulsen, C., Stougaard, P. Eur. J. Biochem. (1989)
- Transcriptional activation at adjacent operators in the divergent-overlapping ilvY and ilvC promoters of Escherichia coli. Wek, R.C., Hatfield, G.W. J. Mol. Biol. (1988)
- An alternative pathway for the biosynthesis of isoprenoid compounds in bacteria. Pandian, S., Saengchjan, S., Raman, T.S. Biochem. J. (1981)
- Sulfometuron methyl-sensitive and -resistant acetolactate synthases of the archaebacteria Methanococcus spp. Xing, R.Y., Whitman, W.B. J. Bacteriol. (1987)
- ilvB-encoded acetolactate synthase is resistant to the herbicide sulfometuron methyl. LaRossa, R.A., Smulski, D.R. J. Bacteriol. (1984)
- Branched-chain amino acid biosynthesis is essential for optimal growth of Streptococcus thermophilus in milk. Garault, P., Letort, C., Juillard, V., Monnet, V. Appl. Environ. Microbiol. (2000)
- A new map location for the ilvB locus of Escherichia coli. Newman, T.C., Levinthal, M. Genetics (1980)
- Towards diacetyl-less brewers' yeast. Influence of ilv2 and ilv5 mutations. Gjermansen, C., Nilsson-Tillgren, T., Petersen, J.G., Kielland-Brandt, M.C., Sigsgaard, P., Holmberg, S. J. Basic Microbiol. (1988)
- Constricted flux through the branched-chain amino acid biosynthetic enzyme acetolactate synthase triggers elevated expression of genes regulated by rpoS and internal acidification. Van Dyk, T.K., Ayers, B.L., Morgan, R.W., Larossa, R.A. J. Bacteriol. (1998)
- Fermentative metabolism is induced by inhibiting different enzymes of the branched-chain amino acid biosynthesis pathway in pea plants. Zabalza, A., González, E.M., Arrese-Igor, C., Royuela, M. J. Agric. Food Chem. (2005)
- Purification, crystallization and preliminary X-ray crystallographic studies on acetolactate decarboxylase. Najmudin, S., Andersen, J.T., Patkar, S.A., Borchert, T.V., Crout, D.H., Fülöp, V. Acta Crystallogr. D Biol. Crystallogr. (2003)
- A nondestructive method for peptide bond conjugation of antigenic haptens to a diphtheria toxoid carrier, exemplified by two antisera specific to acetolactate synthase. Marcussen, J., Poulsen, C. Anal. Biochem. (1991)