Disease relevance of Banarat

• Three different prolin reach peptide sequences, interacting with NCp7, were isolated, from a constrained phage displayed-peptide library of 10(8) independent clones [1].
• Therefore, we tested the culture medium of Streptomyces plicatus for prolin-specific peptidases [2].

High impact information on Banarat

• Prolin-rich tyrosine kinase 2 (PYK2) expression and localization in mouse testis [3].
• Down-regulation of ferredoxin was demonstrated only in the late phase of development of the anaerobic resistance (MR-100) [4].
• The H4P heavy chain of inter-alpha-inhibitor family largely differs in the structure and synthesis of its prolin-rich region from rat to human [5].
• The enzymes of the arginine dihydrolase pathway were measured in Trichomonas vaginalis hydrogenosome-deficient lines MR-5 and MR-100, and the parent strain TV 10-02 [6].
• Inclusion of the ornithine decarboxylase inhibitor difluoromethylornithine in these incubations reduced the CO2 production of strain TV 10-02 by 42%, but only inhibited the MR-100 strain by 14.5%, indicative that the majority of the CO2 liberated from arginine by this strain is derived from the elevated activity of ornithine carbamyltransferase [6].

Biological context of Banarat

• All nodes identified by gamma probe (MR 100 Pol.Hi.Tech) were histologically evaluated by immunohistochemistry and standard histology [7].

Gene context of Banarat

• It is suggested that prolin is an essential constituent of amelogenin and therefore its positions in the molecule have been conserved after the evolutionary divergence of reptiles and mammals [8].
• A 350 mm laparoscopic gamma scintyprobe MR 100 type 11, 99mTc settled (Pol Hi Tech), was used intraoperatively for SLN detection [9].

Analytical, diagnostic and therapeutic context of Banarat

• During thoracoscopy a 11 mm diameter-collimated probe connected to a gamma ray detector (Scinti Probe MR 100 - Pol. hi.tech., Aquila - Italy), is introduced by a 11.5 mm trocar and the pleural surface of the suspected area was scanned [10].
• Contralateral and ipsilateral lymphatic areas were scanned with a hand-held gamma camera (Scintiprobe MR 100) to measure the background and identify the hot point indicating the location of the sentinel node to direct the incision [11].

References