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Chemical Compound Review

Banarat     4-amino-N-quinoxalin-2-yl...

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Disease relevance of Banarat

  • Three different prolin reach peptide sequences, interacting with NCp7, were isolated, from a constrained phage displayed-peptide library of 10(8) independent clones [1].
  • Therefore, we tested the culture medium of Streptomyces plicatus for prolin-specific peptidases [2].

High impact information on Banarat


Biological context of Banarat


Gene context of Banarat

  • It is suggested that prolin is an essential constituent of amelogenin and therefore its positions in the molecule have been conserved after the evolutionary divergence of reptiles and mammals [8].
  • A 350 mm laparoscopic gamma scintyprobe MR 100 type 11, 99mTc settled (Pol Hi Tech), was used intraoperatively for SLN detection [9].

Analytical, diagnostic and therapeutic context of Banarat

  • During thoracoscopy a 11 mm diameter-collimated probe connected to a gamma ray detector (Scinti Probe MR 100 - Pol., Aquila - Italy), is introduced by a 11.5 mm trocar and the pleural surface of the suspected area was scanned [10].
  • Contralateral and ipsilateral lymphatic areas were scanned with a hand-held gamma camera (Scintiprobe MR 100) to measure the background and identify the hot point indicating the location of the sentinel node to direct the incision [11].


  1. Use of a constrain phage displayed-peptide library for the isolation of peptides binding to HIV-1 nucleocapsid protein (NCp7). Lener, D., Benarous, R., Calogero, R.A. FEBS Lett. (1995) [Pubmed]
  2. Purification and properties of an iminopeptidase from culture media of Streptomyces plicatus. Ehrenfreund, P., Mollay, C., Kreil, G. Biochem. Biophys. Res. Commun. (1992) [Pubmed]
  3. Prolin-rich tyrosine kinase 2 (PYK2) expression and localization in mouse testis. Chieffi, P., Barchi, M., Di Agostino, S., Rossi, P., Tramontano, D., Geremia, R. Mol. Reprod. Dev. (2003) [Pubmed]
  4. Metronidazole-resistant strains of Trichomonas vaginalis display increased susceptibility to oxygen. Rasoloson, D., Tomková, E., Cammack, R., Kulda, J., Tachezy, J. Parasitology (2001) [Pubmed]
  5. The H4P heavy chain of inter-alpha-inhibitor family largely differs in the structure and synthesis of its prolin-rich region from rat to human. Soury, E., Olivier, E., Daveau, M., Hiron, M., Claeyssens, S., Risler, J.L., Salier, J.P. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  6. The contribution of the arginine dihydrolase pathway to energy metabolism by Trichomonas vaginalis. Yarlett, N., Martinez, M.P., Moharrami, M.A., Tachezy, J. Mol. Biochem. Parasitol. (1996) [Pubmed]
  7. Sentinel lymph node identification in breast cancer: feasibility study. Motta, C., Cartia, G., Muni, A., Giudici, M., Falcetto, G., Castaldo, P., Galli, T. Tumori. (2000) [Pubmed]
  8. Amelogenin protein in tooth germs of the snake Elaphe quadrivirgata, immunohistochemistry, cloning and cDNA sequence. Ishiyama, M., Mikami, M., Shimokawa, H., Oida, S. Arch. Histol. Cytol. (1998) [Pubmed]
  9. Preliminary study of sentinel node identification with 99mTc colloid and blue dye in patients with endometrial cancer. Pelosi, E., Arena, V., Baudino, B., Bellò, M., Gargiulo, T., Giusti, M., Bottero, A., Leo, L., Armellino, F., Palladin, D., Bisi, G. Tumori. (2002) [Pubmed]
  10. A pilot study of the role of TC-99 radionuclide in localization of pulmonary nodular lesions for thoracoscopic resection. Chella, A., Lucchi, M., Ambrogi, M.C., Menconi, G., Melfi, F.M., Gonfiotti, A., Boni, G., Angeletti, C.A. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. (2000) [Pubmed]
  11. Reliability and accuracy of sentinel node biopsy in cutaneous malignant melanoma. Carcoforo, P., Soliani, G., Bergossi, L., Basaglia, E., Virgili, A.R., Pagani, W., Pozza, E., Feggi, L.M. Tumori. (2002) [Pubmed]
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