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Chemical Compound Review

3,3'-DICHLOROBENZIDINE     4-(4-amino-3-chloro-phenyl)- 2-chloro-aniline

Synonyms: Curithane C126, CCRIS 220, SureCN49382, CHEMBL314470, AG-H-77539, ...
 
 
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Disease relevance of 3,3'-DICHLOROBENZIDINE

 

High impact information on 3,3'-DICHLOROBENZIDINE

 

Biological context of 3,3'-DICHLOROBENZIDINE

 

Anatomical context of 3,3'-DICHLOROBENZIDINE

 

Associations of 3,3'-DICHLOROBENZIDINE with other chemical compounds

 

Gene context of 3,3'-DICHLOROBENZIDINE

 

Analytical, diagnostic and therapeutic context of 3,3'-DICHLOROBENZIDINE

References

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  2. Activation of 3,3'-dichlorobenzidine in rat liver microsomes to mutagens: involvement of cytochrome P-450d. Iba, M.M., Thomas, P.E. Carcinogenesis (1988) [Pubmed]
  3. Covalent interaction of 3,3'-dichlorobenzidine with hepatic lipids. Enzymic basis and stability of the adducts. Iba, M.M., Lang, B., Thomas, P.E., Ghosal, A. Biochem. Pharmacol. (1990) [Pubmed]
  4. Stimulation of the conjugation of lipid dienes in hepatic microsomes by 3,3'-dichlorobenzidine. Iba, M.M., Lang, B. Biochem. Pharmacol. (1988) [Pubmed]
  5. Assessment of genotoxicity of benzidine and its structural analogues to human lymphocytes using comet assay. Chen, S.C., Kao, C.M., Huang, M.H., Shih, M.K., Chen, Y.L., Huang, S.P., Liu, T.Z. Toxicol. Sci. (2003) [Pubmed]
  6. Determination of hemoglobin adducts formed in rats exposed orally with 3,3'-dichlorobenzidine by GC/MS-SIM. Lee, J.H., Shin, H.S. Toxicology and industrial health. (2002) [Pubmed]
  7. Mutagenicity of some congeners of benzidine in the Salmonella typhimurium assay system. Lazear, E.J., Louie, S.C. Cancer Lett. (1978) [Pubmed]
  8. Biomonitoring of aromatic amines V: acetylation and deacetylation in the metabolic activation of aromatic amines as determined by haemoglobin binding. Zwirner-Baier, I., Neumann, H.G. Arch. Toxicol. (1998) [Pubmed]
  9. In vivo binding of 3,3'-dichlorobenzidine to rat and mouse tissue DNA. Ghosal, A., Iba, M.M. Cancer Lett. (1990) [Pubmed]
  10. Effect of acute 3,3'-dichlorobenzidine administration on rat hepatic enzymic and nonenzymic microsomal lipid peroxidation and antioxidant status. Iba, M.M. Res. Commun. Chem. Pathol. Pharmacol. (1987) [Pubmed]
  11. Light-induced mutagenicity in Salmonella TA102 and genotoxicity/cytotoxicity in human T-cells by 3,3'-dichlorobenzidine: a chemical used in the manufacture of dyes and pigments and in tattoo inks. Wang, L., Yan, J., Hardy, W., Mosley, C., Wang, S., Yu, H. Toxicology (2005) [Pubmed]
  12. Benzidine and 3,3'-dichlorobenzidine (DCB) induce micronuclei in the bone marrow and the fetal liver of mice after gavage. Cihák, R., Vontorková, M. Mutagenesis (1987) [Pubmed]
  13. Metabolism of 3,3'-dichlorobenzidine by horseradish peroxidase. Lang, B., Iba, M.M. Xenobiotica (1988) [Pubmed]
  14. Hydroperoxidase I catalyzes peroxidative activation of 3,3'-dichlorobenzidine to a mutagen in Salmonella typhimurium. McGowan-Jordan, I.J., Josephy, P.D. Arch. Biochem. Biophys. (1990) [Pubmed]
  15. The generation of aerosols of carcinogenic aromatic amines. Rappaport, S.M., Gettemy, D.J. American Industrial Hygiene Association journal. (1978) [Pubmed]
  16. Development and evaluation of a microtiter plate enzyme immunoassay for antibodies to 3,3'-dichlorobenzidine. Spierto, F.W., Vogt, R., Whitfield, W., Powell, M.K., Gardner, F.H., Hannon, W.H. Journal of analytical toxicology. (1987) [Pubmed]
  17. Determination of dichlorobenzidine-hemoglobin adducts by GC/MS-NCI. Joppich-Kuhn, R., Hänggi, R., Sagelsdorff, P., Smith, A.E., Weideli, H.J., Joppich, M. International archives of occupational and environmental health. (1997) [Pubmed]
  18. Trace-level determination of benzidine and 3,3'-dichlorobenzidine in aqueous environmental samples by online solid-phase extraction and liquid chromatography with electrochemical detection. Vera-Avila, L.E., García-Ac, A., Covarrubias-Herrera, R. Journal of chromatographic science. (2001) [Pubmed]
 
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