Gene Review:
Cyp1a2 - cytochrome P450, family 1, subfamily a,...
Rattus norvegicus
Synonyms:
CYPD45, CYPIA2, Cyp1a-2, Cytochrome P-448, Cytochrome P-450d, ...
- Halogenated biphenyls as AHH inducers: effects of different halogen substituents. Bandiera, S., Sawyer, T., Campbell, M.A., Robertson, L., Safe, S. Life Sci. (1982)
- Upregulation of cytochrome P450 1A2 in chronic renal failure: does oxidized tryptophan play a role? Sindhu, R.K., Vaziri, N.D. Adv. Exp. Med. Biol. (2003)
- Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates. Kato, R. Crit. Rev. Toxicol. (1986)
- Effects of model traumatic injury on hepatic drug metabolism in the rat. VI. Major detoxification/toxification pathways. Griffeth, L.K., Rosen, G.M., Rauchman, E.J. Drug Metab. Dispos. (1987)
- Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity. Bandiera, S., Sawyer, T., Romkes, M., Zmudzka, B., Safe, L., Mason, G., Keys, B., Safe, S. Toxicology (1984)
- Evidence for the catabolism of polychlorinated biphenyl-induced cytochrome P-448 by microsomal heme oxygenase, and the inhibition of delta-aminolevulinate dehydratase by polychlorinated biphenyls. Maines, M.D. J. Exp. Med. (1976)
- Detection of carcinogen-induced stimulation of cytochrome P-448-associated enzymes by 14CO2 breath analysis studies using dimethylaminoazobenzene. Hepner, G.W., Piken, E.P. Gastroenterology (1979)
- Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver. Kawajiri, K., Gotoh, O., Sogawa, K., Tagashira, Y., Muramatsu, M., Fujii-Kuriyama, Y. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Inhibition of 2-aminofluorene mutagenesis in bacteria by inducers of cytochrome P-450d. Miller, D.M., Aust, A.E., Voorman, R., Aust, S.D. Carcinogenesis (1988)
- Restoration of hydroperoxide-dependent lipid peroxidation by 3-methylcholanthrene induction of cytochrome P-448 in hepatoma microsomes. Borrello, S., Galeotti, T., Palombini, G., Minotti, G. FEBS Lett. (1986)
- Identification of the hepatic cytochrome P-450 isozymes induced and decreased by picloram. Reidy, G.F., Murray, M., Rose, H.A., Bonin, A.M., Baker, R.S., Stacey, N.H. Biochem. Pharmacol. (1988)
- Induction of cytochrome P-448 isozyme(s) in primary cultured rat hepatocytes by drugs which induce different isozymes in vivo. Hishinuma, T., Degawa, M., Masuko, T., Hashimoto, Y. Biochem. Biophys. Res. Commun. (1987)
- Evidence for the involvement of cytochrome P-450-dependent monooxygenase(s) in the formation of genotoxic metabolites from N-hydroxyurea. Andrae, U. Biochem. Biophys. Res. Commun. (1984)
- A mechanistic model of effects of dioxin on gene expression in the rat liver. Kohn, M.C., Lucier, G.W., Clark, G.C., Sewall, C., Tritscher, A.M., Portier, C.J. Toxicol. Appl. Pharmacol. (1993)
- Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat. Sogawa, K., Gotoh, O., Kawajiri, K., Harada, T., Fujii-Kuriyama, Y. J. Biol. Chem. (1985)
- Identification of cytochrome P-450 isozymes involved in the hydroxylation of dantrolene by rat liver microsomes. Jayyosi, Z., Villoutreix, J., Ziegler, J.M., Batt, A.M., De Maack, F., Siest, G., Thomas, P.E. Drug Metab. Dispos. (1993)
- Expression of cytochrome P-450s and glutathione S-transferases in the rat liver during water deprivation: effects of glucose supplementation. Kim, S.G., Kim, E.J., Kim, Y.G., Lee, M.G. Journal of applied toxicology : JAT. (2001)
- Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum. Iba, M.M., Storch, A., Ghosal, A., Bennett, S., Reuhl, K.R., Lowndes, H.E. Arch. Toxicol. (2003)
- The primary structure of cytochrome P-450d purified from rat liver microsomes: prediction of helical regions and domain analysis. Haniu, M., Ryan, D.E., Levin, W., Shively, J.E. Arch. Biochem. Biophys. (1986)
- Selective expression and induction of cytochrome P450PB and P450MC during the development of hereditary hepatitis and hepatoma of LEC rats. Sugiyama, T., Suzuki, K., Ookawara, T., Kurosawa, T., Taniguchi, N. Carcinogenesis (1989)
- Multiplicity of cytochrome P-450 in primary fetal hepatocytes in culture. Kremers, P., Goujon, F., De Graeve, J., Van Cantfort, J., Gielen, J.E. Eur. J. Biochem. (1981)
- Molecular cloning of a complementary DNA to 3-methylcholanthrene-inducible cytochrome P-450 mRNA from rat liver. Kawajiri, K., Sogawa, K., Gotoh, O., Tagashira, Y., Muramatsu, M., Fujii-Kuriyama, Y. J. Biochem. (1983)
- Indolo[3,2-b]carbazole inhibits gap junctional intercellular communication in rat primary hepatocytes and acts as a potential tumor promoter. Herrmann, S., Seidelin, M., Bisgaard, H.C., Vang, O. Carcinogenesis (2002)
- Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole. Botelho, L.H., Ryan, D.E., Yuan, P.M., Kutny, R., Shively, J.E., Levin, W. Biochemistry (1982)
- Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl. Yun, C.H., Hammons, G.J., Jones, G., Martin, M.V., Hopkins, N.E., Alworth, W.L., Guengerich, F.P. Biochemistry (1992)
- Ethanol interferes with regeneration-associated changes in biotransforming enzymes: a potential mechanism underlying ethanol's carcinogenicity? Diehl, A.M., Bisgaard, H.C., Kren, B.T., Steer, C.J. Hepatology (1991)
- Dihydralazine-induced inactivation of cytochrome P450 enzymes in rat liver microsomes. Masubuchi, Y., Horie, T. Drug Metab. Dispos. (1998)
- Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7 alpha-hydroxylase activity. Arlotto, M.P., Greenway, D.J., Parkinson, A. Arch. Biochem. Biophys. (1989)
- On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes. Fujita, V.S., Black, S.D., Tarr, G.E., Koop, D.R., Coon, M.J. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Epoxidation reactions catalyzed by rat liver cytochromes P-450 and P-448 occur at different faces of the 8,9-double bond of 8-methylbenz[a]anthracene. Yang, S.K., Chou, M.W., Fu, P.P., Wislocki, P.G., Lu, A.H. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver. Yoshizawa, H., Uchimaru, R., Kamataki, T., Kato, R., Ueno, Y. Cancer Res. (1982)
- Activation of 3,3'-dichlorobenzidine in rat liver microsomes to mutagens: involvement of cytochrome P-450d. Iba, M.M., Thomas, P.E. Carcinogenesis (1988)
- Induction of cytochrome P450 1A2 by musk analogues and other inducing agents in rat liver. Iwata, N., Suzuki, K., Minegishi, K., Kawanishi, T., Hara, S., Endo, T., Takahashi, A. Eur. J. Pharmacol. (1993)
- Differential effects of nonhydroxylated flavonoids as inducers of cytochrome P450 1A and 2B isozymes in rat liver. Canivenc-Lavier, M.C., Bentejac, M., Miller, M.L., Leclerc, J., Siess, M.H., Latruffe, N., Suschetet, M. Toxicol. Appl. Pharmacol. (1996)
- The influence of age on the inducibility of rat liver cytochrome P450IA1 (CYPIA1) and P450IA2 (CYPIA2) mRNAs. Horbach, G.J., Van Asten, J.G., Van Bezooijen, C.F. Mutat. Res. (1990)