Gene Review:
MAP4K5 - mitogen-activated protein kinase kinase...
Homo sapiens
Synonyms:
GCKR, KHS, KHS1, Kinase homologous to SPS1/STE20, MAPK/ERK kinase kinase kinase 5, ...
- Isolation of the enhanced neurovirulent HSV-1 strains from Korean patients. Kim, J.K., Kim, Y.K., Hong, J., Kim, S.Y., Lee, C.K., Kim, C.J., Kim, Y.S., Ahn, J.K. Virus Genes (2003)
- The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes. Shi, C.S., Huang, N.N., Harrison, K., Han, S.B., Kehrl, J.H. Mol. Cell. Biol. (2006)
- Adaptor proteins CRK and CRKL associate with the serine/threonine protein kinase GCKR promoting GCKR and SAPK activation. Shi, C.S., Tuscano, J., Kehrl, J.H. Blood (2000)
- GCKR links the Bcr-Abl oncogene and Ras to the stress-activated protein kinase pathway. Shi, C.S., Tuscano, J.M., Witte, O.N., Kehrl, J.H. Blood (1999)
- The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins. Oehrl, W., Kardinal, C., Ruf, S., Adermann, K., Groffen, J., Feng, G.S., Blenis, J., Tan, T.H., Feller, S.M. Oncogene (1998)
- Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA. Zhang, Y.A., Nemunaitis, J., Samuel, S.K., Chen, P., Shen, Y., Tong, A.W. Cancer Res. (2006)
- The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai. Gu, Y., Luo, T., Yang, J., Zhang, D., Dai, M., Jian, W., Zheng, S., Zhou, W., Zhou, W., Wu, Y., Liu, Y., Liu, Y., Li, J., Xie, X., Li, G., Luo, M. J. Hum. Genet. (2006)