Gene Review:
Alx4 - aristaless-like homeobox 4
Mus musculus
Synonyms:
ALX-4, Aristaless-like 4, Homeobox protein aristaless-like 4, lst
- Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice. Beverdam, A., Brouwer, A., Reijnen, M., Korving, J., Meijlink, F. Development (2001)
- Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. Qu, S., Niswender, K.D., Ji, Q., van der Meer, R., Keeney, D., Magnuson, M.A., Wisdom, R. Development (1997)
- Haploinsufficiency of ALX4 as a potential cause of parietal foramina in the 11p11.2 contiguous gene-deletion syndrome. Wu, Y.Q., Badano, J.L., McCaskill, C., Vogel, H., Potocki, L., Shaffer, L.G. Am. J. Hum. Genet. (2000)
- Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes. Kuijper, S., Beverdam, A., Kroon, C., Brouwer, A., Candille, S., Barsh, G., Meijlink, F. Development (2005)
- The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development. Takahashi, M., Tamura, K., Büscher, D., Masuya, H., Yonei-Tamura, S., Matsumoto, K., Naitoh-Matsuo, M., Takeuchi, J., Ogura, K., Shiroishi, T., Ogura, T., Belmonte, J.C. Development (1998)
- Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. Dunn, N.R., Winnier, G.E., Hargett, L.K., Schrick, J.J., Fogo, A.B., Hogan, B.L. Dev. Biol. (1997)
- Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh. Kuijper, S., Feitsma, H., Sheth, R., Korving, J., Reijnen, M., Meijlink, F. Dev. Biol. (2005)
- Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. Antonopoulou, I., Mavrogiannis, L.A., Wilkie, A.O., Morriss-Kay, G.M. J. Anat. (2004)
- Alx4 binding to LEF-1 regulates N-CAM promoter activity. Boras, K., Hamel, P.A. J. Biol. Chem. (2002)
- Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Rice, R., Rice, D.P., Olsen, B.R., Thesleff, I. Dev. Biol. (2003)
- Survey for paired-like homeodomain gene expression in the hypothalamus: restricted expression patterns of Rx, Alx4 and goosecoid. Asbreuk, C.H., van Schaick, H.S., Cox, J.J., Smidt, M.P., Burbach, J.P. Neuroscience (2002)
- Alx-4, a transcriptional activator whose expression is restricted to sites of epithelial-mesenchymal interactions. Hudson, R., Taniguchi-Sidle, A., Boras, K., Wiggan, O., Hamel, P.A. Dev. Dyn. (1998)
- Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein. Qu, S., Li, L., Wisdom, R. Gene (1997)
- Site-specific heterodimerization by paired class homeodomain proteins mediates selective transcriptional responses. Tucker, S.C., Wisdom, R. J. Biol. Chem. (1999)
- Genetic interaction between Lef1 and Alx4 is required for early embryonic development. Boras-Granic, K., Grosschedl, R., Hamel, P.A. Int. J. Dev. Biol. (2006)
- Genetic interaction of Gli3 and Alx4 during limb development. Panman, L., Drenth, T., Tewelscher, P., Zuniga, A., Zeller, R. Int. J. Dev. Biol. (2005)
- Hoxb2 and hoxb4 act together to specify ventral body wall formation. Manley, N.R., Barrow, J.R., Zhang, T., Capecchi, M.R. Dev. Biol. (2001)
- Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly. Qu, S., Tucker, S.C., Ehrlich, J.S., Levorse, J.M., Flaherty, L.A., Wisdom, R., Vogt, T.F. Development (1998)