Gene Review:
gag-pol - Gag-Pol
Simian immunodeficiency virus
- Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara. Hirsch, V.M., Fuerst, T.R., Sutter, G., Carroll, M.W., Yang, L.C., Goldstein, S., Piatak, M., Elkins, W.R., Alvord, W.G., Montefiori, D.C., Moss, B., Lifson, J.D. J. Virol. (1996)
- Immunization with recombinant modified vaccinia virus Ankara can modify mucosal simian immunodeficiency virus infection and delay disease progression in macaques. Nilsson, C., Sutter, G., Walther-Jallow, L., ten Haaft, P., Akerblom, L., Heeney, J., Erfle, V., Böttiger, P., Biberfeld, G., Thorstensson, R. J. Gen. Virol. (2002)
- Recombinant canarypox vaccine-elicited CTL specific for dominant and subdominant simian immunodeficiency virus epitopes in rhesus monkeys. Santra, S., Schmitz, J.E., Kuroda, M.J., Lifton, M.A., Nickerson, C.E., Lord, C.I., Pal, R., Franchini, G., Letvin, N.L. J. Immunol. (2002)
- Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors. Wagner, R., Graf, M., Bieler, K., Wolf, H., Grunwald, T., Foley, P., Uberla, K. Hum. Gene Ther. (2000)
- Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. Earl, P.L., Wyatt, L.S., Montefiori, D.C., Bilska, M., Woodward, R., Markham, P.D., Malley, J.D., Vogel, T.U., Allen, T.M., Watkins, D.I., Miller, N., Moss, B. Virology (2002)
- A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability. Lützelberger, M., Reinert, L.S., Das, A.T., Berkhout, B., Kjems, J. J. Biol. Chem. (2006)
- In vitro characterization of the interaction between HIV-1 Gag and human lysyl-tRNA synthetase. Kovaleski, B.J., Kennedy, R., Hong, M.K., Datta, S.A., Kleiman, L., Rein, A., Musier-Forsyth, K. J. Biol. Chem. (2006)
- A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors. Cockrell, A.S., Ma, H., Fu, K., McCown, T.J., Kafri, T. Mol. Ther. (2006)
- Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV. Ourmanov, I., Brown, C.R., Moss, B., Carroll, M., Wyatt, L., Pletneva, L., Goldstein, S., Venzon, D., Hirsch, V.M. J. Virol. (2000)
- Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge. Seth, A., Ourmanov, I., Schmitz, J.E., Kuroda, M.J., Lifton, M.A., Nickerson, C.E., Wyatt, L., Carroll, M., Moss, B., Venzon, D., Letvin, N.L., Hirsch, V.M. J. Virol. (2000)
- Gag-Pol bearing a reverse transcriptase drug-resistant mutation influences viral genomic RNA incorporation into human immunodeficiency virus type 1 particles. Aguiar, R.S., Pereira, H.S., Costa, L.J., Brindeiro, R.M., Tanuri, A. J. Gen. Virol. (2006)
- Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage. Strappe, P.M., Hampton, D.W., Brown, D., Cachon-Gonzalez, B., Caldwell, M., Fawcett, J.W., Lever, A.M. Retrovirology (2005)
- Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity. Sharpe, S., Polyanskaya, N., Dennis, M., Sutter, G., Hanke, T., Erfle, V., Hirsch, V., Cranage, M. J. Gen. Virol. (2001)