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MeSH Review

Simian immunodeficiency virus

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Gene context of Simian immunodeficiency virus


Analytical, diagnostic and therapeutic context of Simian immunodeficiency virus


  1. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Deng, H.K., Unutmaz, D., KewalRamani, V.N., Littman, D.R. Nature (1997) [Pubmed]
  2. Human infection by genetically diverse SIVSM-related HIV-2 in west Africa. Gao, F., Yue, L., White, A.T., Pappas, P.G., Barchue, J., Hanson, A.P., Greene, B.M., Sharp, P.M., Shaw, G.M., Hahn, B.H. Nature (1992) [Pubmed]
  3. Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine. Tsai, C.C., Follis, K.E., Sabo, A., Beck, T.W., Grant, R.F., Bischofberger, N., Benveniste, R.E., Black, R. Science (1995) [Pubmed]
  4. 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase. Balzarini, J., Pérez-Pérez, M.J., San-Félix, A., Schols, D., Perno, C.F., Vandamme, A.M., Camarasa, M.J., De Clercq, E. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  5. Proliferation and apoptosis-related gene expression in experimental acquired immunodeficiency syndrome-related simian lymphoma. Castaños-Vélez, E., Heiden, T., Ekman, M., Lawrence, J., Biberfeld, G., Biberfeld, P. Blood (1999) [Pubmed]
  6. Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs. Czub, S., Czub, M., Koutsilieri, E., Sopper, S., Villinger, F., Müller, J.G., Stahl-Hennig, C., Riederer, P., Ter Meulen, V., Gosztonyi, G. Acta Neuropathol. (2004) [Pubmed]
  7. HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Wolf, D., Witte, V., Laffert, B., Blume, K., Stromer, E., Trapp, S., d'Aloja, P., Schürmann, A., Baur, A.S. Nat. Med. (2001) [Pubmed]
  8. HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo. Goh, W.C., Rogel, M.E., Kinsey, C.M., Michael, S.F., Fultz, P.N., Nowak, M.A., Hahn, B.H., Emerman, M. Nat. Med. (1998) [Pubmed]
  9. Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Lang, S.M., Iafrate, A.J., Stahl-Hennig, C., Kuhn, E.M., Nisslein, T., Kaup, F.J., Haupt, M., Hunsmann, G., Skowronski, J., Kirchhoff, F. Nat. Med. (1997) [Pubmed]
  10. CD4-independent binding of SIV gp120 to rhesus CCR5. Martin, K.A., Wyatt, R., Farzan, M., Choe, H., Marcon, L., Desjardins, E., Robinson, J., Sodroski, J., Gerard, C., Gerard, N.P. Science (1997) [Pubmed]
  11. Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2. Henderson, L.E., Sowder, R.C., Copeland, T.D., Benveniste, R.E., Oroszlan, S. Science (1988) [Pubmed]
  12. An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. Sauter, M.M., Pelchen-Matthews, A., Bron, R., Marsh, M., LaBranche, C.C., Vance, P.J., Romano, J., Haggarty, B.S., Hart, T.K., Lee, W.M., Hoxie, J.A. J. Cell Biol. (1996) [Pubmed]
  13. The human and simian immunodeficiency virus envelope glycoprotein transmembrane subunits are palmitoylated. Yang, C., Spies, C.P., Compans, R.W. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  14. CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Pushkarsky, T., Zybarth, G., Dubrovsky, L., Yurchenko, V., Tang, H., Guo, H., Toole, B., Sherry, B., Bukrinsky, M. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  15. Electrostatic interactions modulate the RNA-binding and transactivation specificities of the human immunodeficiency virus and simian immunodeficiency virus Tat proteins. Tao, J., Frankel, A.D. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  16. Social stress results in altered glucocorticoid regulation and shorter survival in simian acquired immune deficiency syndrome. Capitanio, J.P., Mendoza, S.P., Lerche, N.W., Mason, W.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  17. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. Benson, R.E., Sanfridson, A., Ottinger, J.S., Doyle, C., Cullen, B.R. J. Exp. Med. (1993) [Pubmed]
  18. Upregulation of Fas ligand by simian immunodeficiency virus - a nef-arious mechanism of immune evasion? Johnson, R.P. J. Exp. Med. (1997) [Pubmed]
  19. Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines. Bannert, N., Craig, S., Farzan, M., Sogah, D., Santo, N.V., Choe, H., Sodroski, J. J. Exp. Med. (2001) [Pubmed]
  20. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. Lock, M., Greenberg, M.E., Iafrate, A.J., Swigut, T., Muench, J., Kirchhoff, F., Shohdy, N., Skowronski, J. EMBO J. (1999) [Pubmed]
  21. Nef from pathogenic simian immunodeficiency virus is a negative factor for vaccinia virus. Chan, K.S., Verardi, P.H., Legrand, F.A., Yilma, T.D. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  22. Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells. Sanfridson, A., Hester, S., Doyle, C. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  23. CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Edinger, A.L., Mankowski, J.L., Doranz, B.J., Margulies, B.J., Lee, B., Rucker, J., Sharron, M., Hoffman, T.L., Berson, J.F., Zink, M.C., Hirsch, V.M., Clements, J.E., Doms, R.W. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  24. The stoichiometry of trimeric SIV glycoprotein interaction with CD4 differs from that of anti-envelope antibody Fab fragments. Kim, M., Chen, B., Hussey, R.E., Chishti, Y., Montefiori, D., Hoxie, J.A., Byron, O., Campbell, G., Harrison, S.C., Reinherz, E.L. J. Biol. Chem. (2001) [Pubmed]
  25. Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry. Mori, K., Ringler, D.J., Desrosiers, R.C. J. Virol. (1993) [Pubmed]
  26. Progressive truncations C terminal to the membrane-spanning domain of simian immunodeficiency virus Env reduce fusogenicity and increase concentration dependence of Env for fusion. Lin, X., Derdeyn, C.A., Blumenthal, R., West, J., Hunter, E. J. Virol. (2003) [Pubmed]
  27. Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection. Veazey, R.S., Klasse, P.J., Ketas, T.J., Reeves, J.D., Piatak, M., Kunstman, K., Kuhmann, S.E., Marx, P.A., Lifson, J.D., Dufour, J., Mefford, M., Pandrea, I., Wolinsky, S.M., Doms, R.W., DeMartino, J.A., Siciliano, S.J., Lyons, K., Springer, M.S., Moore, J.P. J. Exp. Med. (2003) [Pubmed]
  28. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blanpain, C., Migeotte, I., Lee, B., Vakili, J., Doranz, B.J., Govaerts, C., Vassart, G., Doms, R.W., Parmentier, M. Blood (1999) [Pubmed]
  29. APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. Yu, Q., Chen, D., König, R., Mariani, R., Unutmaz, D., Landau, N.R. J. Biol. Chem. (2004) [Pubmed]
  30. The function of simian chemokine receptors in the replication of SIV. Marx, P.A., Chen, Z. Semin. Immunol. (1998) [Pubmed]
  31. Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara. Hirsch, V.M., Fuerst, T.R., Sutter, G., Carroll, M.W., Yang, L.C., Goldstein, S., Piatak, M., Elkins, W.R., Alvord, W.G., Montefiori, D.C., Moss, B., Lifson, J.D. J. Virol. (1996) [Pubmed]
  32. Adoptive transfer of simian immunodeficiency virus (SIV) naïve autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status. Villinger, F., Brice, G.T., Mayne, A.E., Bostik, P., Mori, K., June, C.H., Ansari, A.A. Blood (2002) [Pubmed]
  33. Structural variability of the external glycoprotein of simian immunodeficiency virus propagated in cell cultures. Fendrich, C., Lüke, W., Wilde, J., Hunsmann, G. AIDS (1989) [Pubmed]
  34. Site-directed enzyme-linked immunosorbent assay with a synthetic simian immunodeficiency virus SIVmac peptide identifying antibodies against the HIV-2 transmembrane glycoprotein. Norrby, E., Chiodi, F., Whalley, A., Parks, E., Nauclér, A., Costa, C.M., Torstensson, R., Biberfeld, G. AIDS (1989) [Pubmed]
  35. In vitro ethanol suppresses alveolar macrophage TNF-alpha during simian immunodeficiency virus infection. Stoltz, D.A., Nelson, S., Kolls, J.K., Zhang, P., Bohm, R.P., Murphey-Corb, M., Bagby, G.J. Am. J. Respir. Crit. Care Med. (2000) [Pubmed]
  36. Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strains. Edinger, A.L., Blanpain, C., Kunstman, K.J., Wolinsky, S.M., Parmentier, M., Doms, R.W. J. Virol. (1999) [Pubmed]
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