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Gene Review

gpd-1  -  Protein GPD-1

Caenorhabditis elegans

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High impact information on gpd-1


Biological context of gpd-1


Associations of gpd-1 with chemical compounds

  • These results suggest that GAPDH is both an active regulator in the phosphoinositide-mediated signaling pathway and a potential new target for insulin resistance treatment [6].


  1. Intron conservation across the prokaryote-eukaryote boundary: structure of the nuclear gene for chloroplast glyceraldehyde-3-phosphate dehydrogenase from maize. Quigley, F., Martin, W.F., Cerff, R. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  2. Timecourse microarray analyses reveal global changes in gene expression of susceptible Glycine max (soybean) roots during infection by Heterodera glycines (soybean cyst nematode). Alkharouf, N.W., Klink, V.P., Chouikha, I.B., Beard, H.S., Macdonald, M.H., Meyer, S., Knap, H.T., Khan, R., Matthews, B.F. Planta (2006) [Pubmed]
  3. Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae. Lee, Y.H., Huang, X.Y., Hirsh, D., Fox, G.E., Hecht, R.M. Gene (1992) [Pubmed]
  4. Cloning of a trans-spliced glyceraldehyde-3-phosphate-dehydrogenase gene from the potato cyst nematode Globodera rostochiensis and expression of its putative promoter region in Caenorhabditis elegans. Qin, L., Smant, G., Stokkermans, J., Bakker, J., Schots, A., Helder, J. Mol. Biochem. Parasitol. (1998) [Pubmed]
  5. The glyceraldehyde-3-phosphate dehydrogenase gene family in the nematode, Caenorhabditis elegans: isolation and characterization of one of the genes. Yarbrough, P.O., Hayden, M.A., Dunn, L.A., Vermersch, P.S., Klass, M.R., Hecht, R.M. Biochim. Biophys. Acta (1987) [Pubmed]
  6. Forward chemical genetic approach identifies new role for GAPDH in insulin signaling. Min, J., Kyung Kim, Y., Cipriani, P.G., Kang, M., Khersonsky, S.M., Walsh, D.P., Lee, J.Y., Niessen, S., Yates, J.R., Gunsalus, K., Piano, F., Chang, Y.T. Nat. Chem. Biol. (2007) [Pubmed]
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