Gene Review:
GGA3 - golgi-associated, gamma adaptin ear...
Homo sapiens
Synonyms:
ADP-ribosylation factor-binding protein GGA3, Golgi-localized, gamma ear-containing, ARF-binding protein 3, KIAA0154
- Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Tesco, G., Koh, Y.H., Kang, E.L., Cameron, A.N., Das, S., Sena-Esteves, M., Hiltunen, M., Yang, S.H., Zhong, Z., Shen, Y., Simpkins, J.W., Tanzi, R.E. Neuron (2007)
- Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Misra, S., Puertollano, R., Kato, Y., Bonifacino, J.S., Hurley, J.H. Nature (2002)
- Interactions of GGA3 with the ubiquitin sorting machinery. Puertollano, R., Bonifacino, J.S. Nat. Cell Biol. (2004)
- A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking. Scott, G.K., Fei, H., Thomas, L., Medigeshi, G.R., Thomas, G. EMBO J. (2006)
- Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination. Pak, Y., Glowacka, W.K., Bruce, M.C., Pham, N., Rotin, D. J. Cell Biol. (2006)
- Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3. Miller, G.J., Mattera, R., Bonifacino, J.S., Hurley, J.H. Nat. Struct. Biol. (2003)
- Epidermal growth factor-dependent phosphorylation of the GGA3 adaptor protein regulates its recruitment to membranes. Kametaka, S., Mattera, R., Bonifacino, J.S. Mol. Cell. Biol. (2005)
- GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. Dell'Angelica, E.C., Puertollano, R., Mullins, C., Aguilar, R.C., Vargas, J.D., Hartnell, L.M., Bonifacino, J.S. J. Cell Biol. (2000)
- Predominant expression of the short form of GGA3 in human cell lines and tissues. Wakasugi, M., Waguri, S., Kametaka, S., Tomiyama, Y., Kanamori, S., Shiba, Y., Nakayama, K., Uchiyama, Y. Biochem. Biophys. Res. Commun. (2003)
- Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. Kato, Y., Misra, S., Puertollano, R., Hurley, J.H., Bonifacino, J.S. Nat. Struct. Biol. (2002)
- Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. He, X., Zhu, G., Koelsch, G., Rodgers, K.K., Zhang, X.C., Tang, J. Biochemistry (2003)
- A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting. Storch, S., Pohl, S., Braulke, T. J. Biol. Chem. (2004)
- GGA function is required for maturation of neuroendocrine secretory granules. Kakhlon, O., Sakya, P., Larijani, B., Watson, R., Tooze, S.A. EMBO J. (2006)
- The GAT domains of clathrin-associated GGA proteins have two ubiquitin binding motifs. Bilodeau, P.S., Winistorfer, S.C., Allaman, M.M., Surendhran, K., Kearney, W.R., Robertson, A.D., Piper, R.C. J. Biol. Chem. (2004)