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Chemical Compound Review

SureCN70769     (3,4,5,6-tetrahydroxyoxan-2...

Synonyms: AGN-PC-00ACKW, NSC-403338, NSC403338, AR-1H2467, AC1L18PY, ...
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Disease relevance of glucose-6-phosphate


Psychiatry related information on glucose-6-phosphate


High impact information on glucose-6-phosphate


Chemical compound and disease context of glucose-6-phosphate


Biological context of glucose-6-phosphate


Anatomical context of glucose-6-phosphate


Associations of glucose-6-phosphate with other chemical compounds


Gene context of glucose-6-phosphate


Analytical, diagnostic and therapeutic context of glucose-6-phosphate


  1. The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole. Wilson, P.D., Firestone, R.A., Lenard, J. J. Cell Biol. (1987) [Pubmed]
  2. Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells. Harding, C.V., Geuze, H.J. J. Cell Biol. (1992) [Pubmed]
  3. The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic. Scott, G.K., Gu, F., Crump, C.M., Thomas, L., Wan, L., Xiang, Y., Thomas, G. EMBO J. (2003) [Pubmed]
  4. Cholesteryl ester storage disease and Wolman disease: phenotypic variants of lysosomal acid cholesteryl ester hydrolase deficiency. Hoeg, J.M., Demosky, S.J., Pescovitz, O.H., Brewer, H.B. Am. J. Hum. Genet. (1984) [Pubmed]
  5. Correlation between mannose-6-phosphate/IGFII receptor and cathepsin D RNA levels by in situ hybridization in benign and malignant mammary tumors. Zhao, Y., Escot, C., Maudelonde, T., Puech, C., Rouanet, P., Rochefort, H. Cancer Res. (1993) [Pubmed]
  6. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology. Kar, S., Poirier, J., Guevara, J., Dea, D., Hawkes, C., Robitaille, Y., Quirion, R. Neurobiol. Aging (2006) [Pubmed]
  7. A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. Nakagawa, T., Setou, M., Seog, D., Ogasawara, K., Dohmae, N., Takio, K., Hirokawa, N. Cell (2000) [Pubmed]
  8. MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates. Li, J., Aderem, A. Cell (1992) [Pubmed]
  9. Intracellular receptor sorting during endocytosis: comparative immunoelectron microscopy of multiple receptors in rat liver. Geuze, H.J., Slot, J.W., Strous, G.J., Peppard, J., von Figura, K., Hasilik, A., Schwartz, A.L. Cell (1984) [Pubmed]
  10. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Misra, S., Puertollano, R., Kato, Y., Bonifacino, J.S., Hurley, J.H. Nature (2002) [Pubmed]
  11. Estradiol down-regulates the mannose-6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin-D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes. Mathieu, M., Vignon, F., Capony, F., Rochefort, H. Mol. Endocrinol. (1991) [Pubmed]
  12. Molecular and functional analysis of phosphomannomutase (PMM) from higher plants and genetic evidence for the involvement of PMM in ascorbic acid biosynthesis in Arabidopsis and Nicotiana benthamiana. Qian, W., Yu, C., Qin, H., Liu, X., Zhang, A., Johansen, I.E., Wang, D. Plant J. (2007) [Pubmed]
  13. Synthesis, transport and processing of cathepsin C in Morris hepatoma 7777 cells and rat hepatocytes. Mainferme, F., Wattiaux, R., von Figura, K. Eur. J. Biochem. (1985) [Pubmed]
  14. Decreased secretion of Cathepsin D in breast cancer in vivo by tamoxifen: mediated by the mannose-6-phosphate/IGF-II receptor? Dabrosin, C., Johansson, A.C., Ollinger, K. Breast Cancer Res. Treat. (2004) [Pubmed]
  15. Mannose toxicity in Ehrlich ascites tumor cells. Hernández, D., De la Fuente, M. Biochem. Cell Biol. (1989) [Pubmed]
  16. Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene. Wang, Z.Q., Fung, M.R., Barlow, D.P., Wagner, E.F. Nature (1994) [Pubmed]
  17. A single receptor binds both insulin-like growth factor II and mannose-6-phosphate. MacDonald, R.G., Pfeffer, S.R., Coussens, L., Tepper, M.A., Brocklebank, C.M., Mole, J.E., Anderson, J.K., Chen, E., Czech, M.P., Ullrich, A. Science (1988) [Pubmed]
  18. Phosphohexosyl recognition is a general characteristic of pinocytosis of lysosomal glycosidases by human fibroblasts. Kaplan, A., Fischer, D., Achord, D., Sly, W. J. Clin. Invest. (1977) [Pubmed]
  19. The mannose receptor and other macrophage lectins. Stahl, P.D. Curr. Opin. Immunol. (1992) [Pubmed]
  20. Internalization of blocking antibodies against mannose-6-phosphate specific receptors. Gartung, C., Braulke, T., Hasilik, A., von Figura, K. EMBO J. (1985) [Pubmed]
  21. The GGA proteins: adaptors on the move. Bonifacino, J.S. Nat. Rev. Mol. Cell Biol. (2004) [Pubmed]
  22. The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes. Burkhardt, J.K., Wiebel, F.A., Hester, S., Argon, Y. J. Exp. Med. (1993) [Pubmed]
  23. Reversal of infectious mononucleosis-associated suppressor T cell activity by D-mannose. Tosato, G., Pike, S.E., Blaese, R.M. J. Exp. Med. (1983) [Pubmed]
  24. The agent of Human Granulocytic Ehrlichiosis resides in an endosomal compartment. Webster, P., IJdo, J.W., Chicoine, L.M., Fikrig, E. J. Clin. Invest. (1998) [Pubmed]
  25. Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules. Stoolman, L.M., Tenforde, T.S., Rosen, S.D. J. Cell Biol. (1984) [Pubmed]
  26. Kinesin-mediated organelle translocation revealed by specific cellular manipulations. Feiguin, F., Ferreira, A., Kosik, K.S., Caceres, A. J. Cell Biol. (1994) [Pubmed]
  27. Fabry disease: preclinical studies demonstrate the effectiveness of alpha-galactosidase A replacement in enzyme-deficient mice. Ioannou, Y.A., Zeidner, K.M., Gordon, R.E., Desnick, R.J. Am. J. Hum. Genet. (2001) [Pubmed]
  28. Biochemical characterization and intracellular localization of the Menkes disease protein. Yamaguchi, Y., Heiny, M.E., Suzuki, M., Gitlin, J.D. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  29. Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase. Lu, J.Y., Verkruyse, L.A., Hofmann, S.L. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  30. Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Stack, J.H., Horazdovsky, B., Emr, S.D. Annu. Rev. Cell Dev. Biol. (1995) [Pubmed]
  31. Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells. Zhang, Q., Tally, M., Larsson, O., Kennedy, R.T., Huang, L., Hall, K., Berggren, P.O. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  32. Failure to detect genetic alteration of the mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) gene in hepatocellular carcinomas in Japan. Wada, I., Kanada, H., Nomura, K., Kato, Y., Machinami, R., Kitagawa, T. Hepatology (1999) [Pubmed]
  33. Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice. Wutz, A., Theussl, H.C., Dausman, J., Jaenisch, R., Barlow, D.P., Wagner, E.F. Development (2001) [Pubmed]
  34. GGA proteins mediate the recycling pathway of memapsin 2 (BACE). He, X., Li, F., Chang, W.P., Tang, J. J. Biol. Chem. (2005) [Pubmed]
  35. The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae. Brown, W.J., Farquhar, M.G. Cell (1984) [Pubmed]
  36. Expression of the IGF-II/mannose-6-phosphate receptor mRNA and protein in the developing rat. Senior, P.V., Byrne, S., Brammar, W.J., Beck, F. Development (1990) [Pubmed]
  37. Endocytosis of pro-cathepsin D into breast cancer cells is mostly independent of mannose-6-phosphate receptors. Laurent-Matha, V., Farnoud, M.R., Lucas, A., Rougeot, C., Garcia, M., Rochefort, H. J. Cell. Sci. (1998) [Pubmed]
  38. Insulin-like growth factor receptor gene expression in the rat ovary: divergent regulation of distinct receptor species. Hernandez, E.R., Hurwitz, A., Botero, L., Ricciarelli, E., Werner, H., Roberts, C.T., LeRoith, D., Adashi, E.Y. Mol. Endocrinol. (1991) [Pubmed]
  39. Molecular cloning of mannose-6-phosphate reductase and its developmental expression in celery. Everard, J.D., Cantini, C., Grumet, R., Plummer, J., Loescher, W.H. Plant Physiol. (1997) [Pubmed]
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