Gene Review:
Gsta1 - glutathione S-transferase alpha 1
Rattus norvegicus
Synonyms:
Gsta3, Gsta5, Yc1
- Enhancement of radiation-inducible hepatic glutathione-S-transferases Ya, Yb1, Yb2, Yc1, and Yc2 gene expression by oltipraz: possible role in radioprotection. Kim, S.G., Nam, S.Y., Kim, C.W., Kim, J.H., Cho, C.K., Yoo, S.Y. Mol. Pharmacol. (1997)
- Genomic cloning and characterization of the rat glutathione S-transferase-A3-subunit gene. Fotouhi-Ardakani, N., Batist, G. Biochem. J. (1999)
- The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables. Nho, C.W., Jeffery, E. Toxicol. Appl. Pharmacol. (2001)
- Identification of the Yc1 glutathione S-transferase mRNA as the overexpressed species in a nitrogen mustard-resistant rat mammary carcinoma cell line. Fotouhi-Ardakani, N., Woo, A., Lewandowska, M., Schecter, R., Batist, G. J. Biochem. Mol. Toxicol. (1998)
- Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat. Johnson, J.A., Hayward, J.J., Kornguth, S.E., Siegel, F.L. Biochem. J. (1993)
- Increased resistance to nitrogen mustards and antifolates following in vitro selection of murine fibroblasts and primary hematopoietic cells transduced with a bicistronic retroviral vector expressing the rat glutathione S-transferase A3 and a mutant dihydrofolate reductase. Belzile, J.P., Karatzas, A., Shiu, H.Y., Létourneau, S., Palerme, J.S., Cournoyer, D. Cancer Gene Ther. (2003)
- Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide. Hayes, J.D., Judah, D.J., McLellan, L.I., Kerr, L.A., Peacock, S.D., Neal, G.E. Biochem. J. (1991)
- Comparison of the aflatoxin B1-8,9-epoxide conjugating activities of two bacterially expressed alpha class glutathione S-transferase isozymes from mouse and rat. Buetler, T.M., Slone, D., Eaton, D.L. Biochem. Biophys. Res. Commun. (1992)
- Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts. Létourneau, S., Palerme, J.S., Delisle, J.S., Beauséjour, C.M., Momparler, R.L., Cournoyer, D. Cancer Gene Ther. (2000)
- Formation of acetaldehyde adducts of glutathione S-transferase A3 in the liver of rats administered alcohol chronically. Sultana, R., Raju, B.S., Sharma, V., Reddanna, P., Babu, P.P. Alcohol (2005)
- In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. Hu, R., Hebbar, V., Kim, B.R., Chen, C., Winnik, B., Buckley, B., Soteropoulos, P., Tolias, P., Hart, R.P., Kong, A.N. J. Pharmacol. Exp. Ther. (2004)
- Gadolinium chloride inhibition of rat hepatic microsomal epoxide hydrolase and glutathione S-transferase gene expression. Kim, S.G., Choi, S.H. Drug Metab. Dispos. (1997)